Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Arsen V Grigoryan"'
Autor:
Evgeny Shmelkov, Chavdar Krachmarov, Arsen V Grigoryan, Abraham Pinter, Alexander Statnikov, Timothy Cardozo
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e89987 (2014)
The extreme diversity of HIV-1 strains presents a formidable challenge for HIV-1 vaccine design. Although antibodies (Abs) can neutralize HIV-1 and potentially protect against infection, antibodies that target the immunogenic viral surface protein gp
Externí odkaz:
https://doaj.org/article/66a77b485f8d461fb0bff52edfddbdcc
Publikováno v:
PLoS ONE, Vol 7, Iss 10, p e46532 (2012)
The ranking of scores of individual chemicals within a large screening library is a crucial step in virtual screening (VS) for drug discovery. Previous studies showed that the quality of protein-ligand recognition can be improved using spectrum prope
Externí odkaz:
https://doaj.org/article/3ba30ecd30c044f987a55e67722c1798
Autor:
Amin R Mazloom, Ruth Dannenfelser, Neil R Clark, Arsen V Grigoryan, Kathryn M Linder, Timothy J Cardozo, Julia C Bond, Aislyn D W Boran, Ravi Iyengar, Anna Malovannaya, Rainer B Lanz, Avi Ma'ayan
Publikováno v:
PLoS Computational Biology, Vol 7, Iss 12, p e1002319 (2011)
Coregulator proteins (CoRegs) are part of multi-protein complexes that transiently assemble with transcription factors and chromatin modifiers to regulate gene expression. In this study we analyzed data from 3,290 immuno-precipitations (IP) followed
Externí odkaz:
https://doaj.org/article/0cee1b71d698463991acce0891a5005a
Autor:
Arsen V. Grigoryan
Publikováno v:
Annals of Agrarian Science, Vol 15, Iss 2, Pp 235-238 (2017)
In the article the time features of occurrence of bioclimatic and industrial rhythms according to altitudinal belts are analyzed, a nomogram is composed and spatial and time patterns of rhythms are revealed, the ways of the rational use of seasonal r
Publikováno v:
Physics of Atomic Nuclei. 68:1922-1925
The influence of structural inhomogeneity onto order-disorder transitions in 1D systems is considered in the scope of the Potts-like model with many-particle interactions. The helix-coil transition in DNAs, heterogeneous by hydrogen bonding energy, i
Publikováno v:
Physics of Atomic Nuclei. 68:1685-1688
The order-disorder (helix-coil) transition in circular closed DNA (ccDNA) is described on the basis of the open chain DNA (ocDNA) model, proposed earlier, which considers the transition as loop formation. The Hamiltonian of the ccDNA model is constru
Autor:
Eugene Sh. Mamasakhlisov, Chin-Kun Hu, Arsen V. Grigoryan, Artem Badasyan, Shura Hayryan, Vladimir F. Morozov
Publikováno v:
Physica A: Statistical Mechanics and its Applications. 348:327-338
A simplified model for the closed circular DNA (ccDNA) is proposed to describe some specific features of the helix-coil transition in such molecule. The Hamiltonian of ccDNA is related to the one introduced earlier for the linear DNA. The basic assum
Autor:
Artem Badasyan, E. Mamasakhlisov, Vladimir F. Morozov, Mihran A. Sahakyan, Arsen V. Grigoryan
Publikováno v:
Modern Physics Letters B. 19:79-83
We report on theoretical investigation of interactions of different mechanisms and their influence onto DNA cooperativity of helix–coil transition (melting). Using the modified version of microscopic Potts-like one-dimensional model we showed that
Autor:
Mihran A. Sahakyan, Evgeni Sh. Mamasakhlisov, Vladimir F. Morozov, Arsen V. Grigoryan, Artem Badasyan
Publikováno v:
Biopolymers. 75:434-439
By taking into account base-base stacking interactions we improve the Generalized Model of Polypeptide Chain (GMPC). Based on a one-dimensional Potts-like model with many-particle interactions, the GMPC describes the helix-coil transition in both pol
Autor:
Arsen V. Grigoryan, Vladimir F. Morozov, Albert S. Benight, E. Sh. Mamasakhlisov, Artem Badasyan
Publikováno v:
The Journal of chemical physics. 123(19)
A microscopic Potts-like one-dimensional model with many-particle interactions is developed to construct a statistical mechanical description of the melting of heterogeneous sequence duplex DNA. For this model, referred as the generalized model of po