Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Arsênio Rodrigues Oliveira"'
Autor:
Carlos André Laranjeira Miranda Filho, Míria de Oliveira Barbosa, Arsênio Rodrigues Oliveira, Aline Ferreira Pinto, Daniel Lopes Araújo, Jéssica Paula Lucena, Roni Evêncio de Araújo, Sheilla Andrade de Oliveira, Ana Cristina Lima Leite
Publikováno v:
Parasitology research. 121(7)
Schistosomiasis mansoni is considered a serious public health problem. As praziquantel is the only drug recommended by the World Health Organization for the treatment and control of schistosomiasis, the development of new drugs is of great significan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ff8694be2365d4616e193202350b4c1
https://pubmed.ncbi.nlm.nih.gov/35599272
https://pubmed.ncbi.nlm.nih.gov/35599272
Autor:
Sheilla Andrade de Oliveira, Edna de Farias Santiago, Ana Cristina Lima Leite, Paulo André Teixeira de Moraes Gomes, Carlos André Laranjeira Miranda Filho, Fábio André Brayner, Fabiano Amaro de Sousa, Juliana Maria da Conceição, Luiz Carlos Alves, Gevanio Bezerra de Oliveira Filho, Miria de Oliveira Barbosa, Arsênio Rodrigues Oliveira
Publikováno v:
Parasitology Research. 117:2105-2115
Phthalimide, 1,3-thiazole, and thiazolidinone cores are considered privileged scaffolds and represent an attractive starting point to design new bioactive compounds for neglected tropical disease (NTD). Schistosomiasis is a NTD, caused by Schistosoma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05d30871bff8bd1fc60a16218c7759fd
https://doi.org/10.1007/s00436-018-5897-4
https://doi.org/10.1007/s00436-018-5897-4
Autor:
Ana Cristina Lima Leite, Flaviana Alves dos Santos, Marcius Vinicius de Oliveira Silva, Maira Galdino da Rocha Pitta, Moacyr Jesus Barreto de Melo Rêgo, Arsênio Rodrigues Oliveira, Larissa Pelágia de Lima Ferreira, Marcos Veríssimo de Oliveira Cardoso, Pascal Marchand, Aline Ferreira Pinto
Publikováno v:
Chemico-Biological Interactions. 347:109597
In this work, 22 new compounds were obtained and evaluated for their cytotoxic activity on peripheral blood mononuclear cells (PBMC) and eight different tumor cell lines. All compounds displayed IC50 values above 100 μM when assayed against PBMCs. T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21f8b7386581726386b515328bb6224e
https://doi.org/10.1016/j.cbi.2021.109597
https://doi.org/10.1016/j.cbi.2021.109597
Autor:
Arsênio Rodrigues Oliveira, Marcos Veríssimo de Oliveira Cardoso, Carlos A. de Simone, Aline Caroline da Silva, Elany Barbosa da Silva, Thiago André Ramos dos Santos, Valéria Rêgo Alves Pereira, Maria Carolina Acioly de Castro, Rafaela Salgado Ferreira, Ana Cristina Lima Leite, Dayane Albuquerque Oliveira e Silva, Diogo Rodrigo Magalhães Moreira, Carlos Henrique da Silva Mendes
Publikováno v:
European Journal of Medicinal Chemistry. 130:39-50
Chagas disease, caused by the kinetoplastid protozoan parasite Trypanosoma cruzi, remains a relevant cause of illness and premature death and it is estimated that 6 million to 7 million people are infected worldwide. Although chemotherapy options are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c80e664aea5e5eb3a6d627dfbc5bb1f
https://doi.org/10.1016/j.ejmech.2017.02.026
https://doi.org/10.1016/j.ejmech.2017.02.026
Autor:
Carlos André Laranjeira Miranda Filho, Sheilla Andrade de Oliveira, Jéssica Paula Lucena, Ignes Regina Dos Santos, Luiz Carlos Alves, Renata Lins Carneiro Leão, Veruska Cintia Alexandrino de Souza, Valéria Rêgo Alves Pereira, Fábio André Brayner dos Santos, Ana Cristina Lima Leite, Miria de Oliveira Barbosa, Roni Evencio de Araujo, Camila Juliet Barbosa Fernandes, Arsênio Rodrigues Oliveira, Edna de Farias Santiago
Publikováno v:
European Journal of Pharmaceutical Sciences. 146:105236
Schistosomicidal activity of six phthalimido-thiazoles derivatives with substitutions at the position three of the thiazole ring were analyzed in an experimental model. The substituents biphenyl (2i) and 2- naphthyl (2j) at a concentration of 80 µg/
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d58945b8946f8e7a681aff01ede0a32
https://doi.org/10.1016/j.ejps.2020.105236
https://doi.org/10.1016/j.ejps.2020.105236
Autor:
Sheilla Andrade de Oliveira, Fábio André Brayner, Carlos André Laranjeira Miranda Filho, Mabilly Cox Holanda de Barros Dias, Arsênio Rodrigues Oliveira, Miria de Oliveira Barbosa, Jéssica Paula Lucena, Camila Juliet Barbosa Fernandes, Fabiano Amaro de Sousa, Ana Cristina Lima Leite, Luiz Carlos Alves
Publikováno v:
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences. 133
Schistosomiasis is a major public health problem worldwide, especially in poor communities. Praziquantel is currently the only drug available to treat schistosomiasis and it shows low efficacy against schistosomula and juveniles stages of Schistosoma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16878a2cdb516c9e2435f98e67b59b65
https://pubmed.ncbi.nlm.nih.gov/30877068
https://pubmed.ncbi.nlm.nih.gov/30877068
Autor:
Fábio André Brayner, Arsênio Rodrigues Oliveira, Karla Raíza Cardoso Ribeiro, Amanda Silva dos Santos Aliança, Maria Carolina Accioly Brelaz de Castro, Ana Cristina Lima Leite, Luiz Carlos Alves, Ana Paula Sampaio Feitosa
Publikováno v:
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences. 105
It is estimated that the worldwide prevalence of leishmaniasis is around 12 million individuals in 80 countries, with 400,000new cases per year. In the search for new leishmanicidal agents, the hybrid phthalimido-thiazoles have been identified as an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9c69bcc5b84cb1a2a81068d826e9473
https://pubmed.ncbi.nlm.nih.gov/28478133
https://pubmed.ncbi.nlm.nih.gov/28478133
Autor:
Suellen Melo Tibúrcio Cavalcanti, Elizabeth Fernanda de Oliveira Borba, Marcos Veríssimo de Oliveira Cardoso, Teresinha Gonçalves da Silva, Arsênio Rodrigues Oliveira, Gevanio Bezerra de Oliveira Filho, Ana Cristina Lima Leite, Paulo André Teixeira de Moraes Gomes, Lawrence J. Abraham, Belinda J. Kaskow, Lucas Cunha Duarte Coelho, Diogo Rodrigo Magalhães Moreira, Lucianna Rabelo Pessoa de Siqueira, Mahdad Karimi, Miria de Oliveira Barbosa
Publikováno v:
Med. Chem. Commun.. 5:758-765
Modulation of the immune system is an emerging concept in the control of tumor growth. Bearing in mind the pharmacological properties of thalidomide and its phthalimide derivatives, we describe here the structural design, synthesis and pharmacologica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8e6bb330897304ba8b791082bd3b3123
https://doi.org/10.1039/c4md00070f
https://doi.org/10.1039/c4md00070f