Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Arron Mungul"'
Autor:
Ofer Merimsky, Roberta Sanfilippo, Klaus Freivogel, Charlotte Benson, Giovanni Grignani, Ian Judson, Minesh Jobanputra, Dara Stein, Stephanie Manson, Hans Gelderblom, Daniela Katz, Arron Mungul
Publikováno v:
Acta Oncologica, 56(12), 1769-1775
Background: A named patient program (NPP) was designed to provide patients with advanced soft-tissue sarcoma (aSTS) access to pazopanib, a multitargeted tyrosine kinase inhibitor. The SPIRE study was a retrospective chart review of participating pati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1dacdd7d98d617b1db79183f56fe4d97
http://hdl.handle.net/1887/94732
http://hdl.handle.net/1887/94732
Publikováno v:
European Journal of Biochemistry. 271:3623-3634
Several oncogenic proteins are known to influence cellular glycosylation. In particular, transfection of codon 12 point mutated H-Ras increases CMP-Neu5Ac: Galbeta1,4GlcNAc alpha2,6-sialyltransferase I (ST6Gal I) activity in rodent fibroblasts. Given
Publikováno v:
Journal of Mammary Gland Biology and Neoplasia. 6:355-364
Glycosylation is a very important posttranslational modification of many biologically relevant molecules. A change in the structure of glycans added to glycoproteins and glycolipids is a common feature of the change to malignancy. With the cloning of
Publikováno v:
European journal of biochemistry. 271(18)
Several oncogenic proteins are known to influence cellular glycosylation. In particular, transfection of codon 12 point mutated H-Ras increases CMP-Neu5Ac: Galbeta1,4GlcNAc alpha2,6-sialyltransferase I (ST6Gal I) activity in rodent fibroblasts. Given
Autor:
Tim A. Plunkett, Olivera J. Finn, Anda M. Vlad, Arron Mungul, Joyce Taylor-Papadimitriou, Jessica Candelora-Kettel, Isabel Correa, Joy Burchell
MUC1 is a transmembrane mucin that is expressed on ductal epithelial cells and epithelial malignancies and has been proposed as a target antigen for immunotherapy. The expression of MUC1 has recently been reported on T and B cells. In this study we d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::804130d7c67c879aae2de20e5d2342cd
https://europepmc.org/articles/PMC1782871/
https://europepmc.org/articles/PMC1782871/
Autor:
Joyce Taylor-Papadimitriou, Isabel Correa, Joy Burchell, T A Plunkett, Arron Mungul, David Miles, Robert Sewell, Gianfranco Picco
Publikováno v:
Breast Cancer Research : BCR
There are two major reasons for using mouse models for preclinical testing of immunotherapetic strategies before proceeding to clinical trial. First, the requirements of regulatory authorities for toxicity testing and, second, the need of the investi