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Assesment of serum IGF-I concentrations in the diagnosis of isolated childhood-onset GH deficiency: A proposal of the Italian Society for Pediatric Endocrinology and Diabetes (SIEDP/ISPED)

Autor: Federico, G., Street, Me, Maghnie, M, Caruso Nicoletti, M, Loche, S, Bertelloni, S, Cianfarani, S, Cicognani, A, Cesaretti, G, Lorini, R, Meschi, F, de Sanctis, V, Aimarretti, G, Antoniazzi, Franco, Arrigon, T, Bellone, J, Bellone, S, Bertalloni, S, Bozzola, M, Buzi, F, Cappa, M, Cistemino, M, De Luca, F, Del Vecchio, M, Galluzzi, F, Germani, D, Ghirri, P, Ghizzoni, L, Greggio, Na, Lughetti, L, Losi, S, Luciano, A, Maffeis, Claudio, Modestini, E, Pirazzoli, P, Pozzobon, G, Predieri, B, Rusconi, R, Slerno, Mc, Salvatoni, A, Scirè, G, Scommegna, S, Spadoni, Gl, Sposito, M, Wasniewska, Ml, Zampolli, M, Zucchini, S.

The diagnosis of GH deficiency (GHD) is based on the measurement of peak GH responses to pharmacological stimuli. Pharmacological stimuli, however, lack precision, accuracy, are not reproducible, are invasive, non-physiological and some may even be h

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