The SecM arrest peptide traps a pre-peptide bond formation state of the ribosome

Autor: Felix Gersteuer, Martino Morici, Sara Gabrielli, Keigo Fujiwara, Haaris A. Safdari, Helge Paternoga, Lars V. Bock, Shinobu Chiba, Daniel N. Wilson

Publikováno v: Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)

Abstract Nascent polypeptide chains can induce translational stalling to regulate gene expression. This is exemplified by the E. coli secretion monitor (SecM) arrest peptide that induces translational stalling to regulate expression of the downstream

Externí odkaz: https://doaj.org/article/73596d597f1f42cfaa8ac810322d5c48

Publisher Correction: The SecM arrest peptide traps a pre-peptide bond formation state of the ribosome.

Autor: Gersteuer F; Institute for Biochemistry and Molecular Biology, University of Hamburg, Martin-Luther-King-Platz 6, 20146, Hamburg, Germany., Morici M; Institute for Biochemistry and Molecular Biology, University of Hamburg, Martin-Luther-King-Platz 6, 20146, Hamburg, Germany., Gabrielli S; Theoretical and Computational Biophysics Department, Max Planck Institute for Multidisciplinary Sciences, Göttingen, Germany., Fujiwara K; Faculty of Life Sciences and Institute for Protein Dynamics, Kyoto Sangyo University, Kamigamo, Motoyama, Kita-ku, Kyoto, 603-8555, Japan., Safdari HA; Institute for Biochemistry and Molecular Biology, University of Hamburg, Martin-Luther-King-Platz 6, 20146, Hamburg, Germany., Paternoga H; Institute for Biochemistry and Molecular Biology, University of Hamburg, Martin-Luther-King-Platz 6, 20146, Hamburg, Germany., Bock LV; Theoretical and Computational Biophysics Department, Max Planck Institute for Multidisciplinary Sciences, Göttingen, Germany., Chiba S; Faculty of Life Sciences and Institute for Protein Dynamics, Kyoto Sangyo University, Kamigamo, Motoyama, Kita-ku, Kyoto, 603-8555, Japan., Wilson DN; Institute for Biochemistry and Molecular Biology, University of Hamburg, Martin-Luther-King-Platz 6, 20146, Hamburg, Germany. Daniel.Wilson@chemie.uni-hamburg.de.

Publikováno v: Nature communications [Nat Commun] 2024 Apr 16; Vol. 15 (1), pp. 3276. Date of Electronic Publication: 2024 Apr 16.

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.

Exploration of the Arrest Peptide Sequence Space Reveals Arrest-enhanced Variants

Autor: Cymer, Florian, Hedman, Rickard, Ismail, Nurzian, von Heijne, Gunnar

Publikováno v: In Journal of Biological Chemistry 17 April 2015 290(16):10208-10215