Zobrazeno 1 - 10
of 109
pro vyhledávání: '"Arran K. Turnbull"'
Publikováno v:
Breast, Vol 66, Iss , Pp 305-309 (2022)
Background: Mondor's disease is a rare disorder characterised by thrombosis of superficial veins within the subcutaneous tissue of the breast and other organs. While factors such as trauma, infection, physical exertion, breast cancer and breast surge
Externí odkaz:
https://doaj.org/article/2d1eec698800450788ff30cd43403d9b
Autor:
Arran K. Turnbull, Cigdem Selli, Carlos Martinez-Perez, Anu Fernando, Lorna Renshaw, Jane Keys, Jonine D. Figueroa, Xiaping He, Maki Tanioka, Alison F. Munro, Lee Murphy, Angie Fawkes, Richard Clark, Audrey Coutts, Charles M. Perou, Lisa A. Carey, J. Michael Dixon, Andrew H. Sims
Publikováno v:
BMC Bioinformatics, Vol 21, Iss 1, Pp 1-10 (2020)
Abstract Background High-throughput transcriptomics has matured into a very well established and widely utilised research tool over the last two decades. Clinical datasets generated on a range of different platforms continue to be deposited in public
Externí odkaz:
https://doaj.org/article/35931cd60eb849c58eee6a74c308610f
Autor:
Richard J. Bownes, Arran K. Turnbull, Carlos Martinez-Perez, David A. Cameron, Andrew H. Sims, Olga Oikonomidou
Publikováno v:
Breast Cancer Research, Vol 21, Iss 1, Pp 1-12 (2019)
Abstract Background Neoadjuvant chemotherapy is increasingly given preoperatively to shrink breast tumours prior to surgery. This approach also provides the opportunity to study the molecular changes associated with treatment and evaluate whether on-
Externí odkaz:
https://doaj.org/article/222dc75295fc40e39ac1f9367c978a67
Autor:
Mark Gray, Arran K. Turnbull, Carol Ward, James Meehan, Carlos Martínez-Pérez, Maria Bonello, Lisa Y. Pang, Simon P. Langdon, Ian H. Kunkler, Alan Murray, David Argyle
Publikováno v:
Radiation Oncology, Vol 14, Iss 1, Pp 1-19 (2019)
Abstract Background Radiotherapy plays an important role in the multimodal treatment of breast cancer. The response of a breast tumour to radiation depends not only on its innate radiosensitivity but also on tumour repopulation by cells that have dev
Externí odkaz:
https://doaj.org/article/f86ee81a892849e88ed5db0ce297194d
Autor:
Cigdem Selli, Arran K. Turnbull, Dominic A. Pearce, Ang Li, Anu Fernando, Jimi Wills, Lorna Renshaw, Jeremy S. Thomas, J. Michael Dixon, Andrew H. Sims
Publikováno v:
Breast Cancer Research, Vol 21, Iss 1, Pp 1-15 (2019)
Abstract Background The risk of recurrence for endocrine-treated breast cancer patients persists for many years or even decades following surgery and apparently successful adjuvant therapy. This period of dormancy and acquired resistance is inherentl
Externí odkaz:
https://doaj.org/article/fd063ba684234388a49de0f5201f443c
Autor:
Edward J. Jarman, Carol Ward, Arran K. Turnbull, Carlos Martinez-Perez, James Meehan, Chrysi Xintaropoulou, Andrew H. Sims, Simon P. Langdon
Publikováno v:
Breast Cancer Research, Vol 21, Iss 1, Pp 1-18 (2019)
Abstract Background Tumour hypoxia is a driver of breast cancer progression associated with worse prognosis and more aggressive disease. The cellular response to hypoxia is mediated by the hypoxia-inducible transcription factors HIF-1 and HIF-2, whos
Externí odkaz:
https://doaj.org/article/923a851c858a45a7b0788fc90b57314e
Autor:
Mark Gray, Arran K. Turnbull, James Meehan, Carlos Martínez-Pérez, Charlene Kay, Lisa Y. Pang, David J. Argyle
Publikováno v:
Frontiers in Veterinary Science, Vol 8 (2021)
Externí odkaz:
https://doaj.org/article/a79dd117347a4adc9ac16f07111d04e5
Autor:
Mark Gray, James Meehan, Arran K. Turnbull, Carlos Martínez-Pérez, Charlene Kay, Lisa Y. Pang, David J. Argyle
Publikováno v:
Frontiers in Veterinary Science, Vol 7 (2020)
Treating individual patients on the basis of specific factors, such as biomarkers, molecular signatures, phenotypes, environment, and lifestyle is what differentiates the precision medicine initiative from standard treatment regimens. Although precis
Externí odkaz:
https://doaj.org/article/6e073301f12f42c398ad3721d64f089b
Autor:
Mark Gray, Arran K. Turnbull, James Meehan, Carlos Martínez-Pérez, Charlene Kay, Lisa Y. Pang, David J. Argyle
Publikováno v:
Frontiers in Veterinary Science, Vol 7 (2020)
Research using in vitro canine mammary cancer cell lines and naturally-occurring canine mammary tumors are not only fundamental models used to advance the understanding of cancer in veterinary patients, but are also regarded as excellent translationa
Externí odkaz:
https://doaj.org/article/03478e29514d401a9b66e422bfe6cb16
Autor:
Mark Gray, James Meehan, Carlos Martínez-Pérez, Charlene Kay, Arran K. Turnbull, Linda R. Morrison, Lisa Y. Pang, David Argyle
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
Despite extensive research over many decades, human breast cancer remains a major worldwide health concern. Advances in pre-clinical and clinical research has led to significant improvements in recent years in how we manage breast cancer patients. Al
Externí odkaz:
https://doaj.org/article/45c6cc0aec4d4be6b4e8d351cf46508a