Potassium-chelating drug sodium polystyrene sulfonate enhances lysosomal function and suppresses proteotoxicity.

Autor: Arputhasamy C; Buck Institute for Research On Aging, Novato, CA, USA., Foulger AC; Buck Institute for Research On Aging, Novato, CA, USA., Lucanic M; Buck Institute for Research On Aging, Novato, CA, USA., Rane A; Buck Institute for Research On Aging, Novato, CA, USA., Schmidt M; Buck Institute for Research On Aging, Novato, CA, USA.; School of Gerontology, USC Leonard Davis, University of Southern California, Los Angeles, CA, USA., Garrett T; Buck Institute for Research On Aging, Novato, CA, USA., Broussalian M; Buck Institute for Research On Aging, Novato, CA, USA.; Dominican University of California, San Rafael, CA, USA., Battistoni E; Buck Institute for Research On Aging, Novato, CA, USA.; Dominican University of California, San Rafael, CA, USA., Brem RB; Buck Institute for Research On Aging, Novato, CA, USA.; Department of Plant and Microbial Biology, UC Berkeley, Berkeley, CA, USA., Lithgow GJ; Buck Institute for Research On Aging, Novato, CA, USA.; School of Gerontology, USC Leonard Davis, University of Southern California, Los Angeles, CA, USA., Chamoli M; Buck Institute for Research On Aging, Novato, CA, USA. mchamoli@buckinstitute.org., Andersen JK; Buck Institute for Research On Aging, Novato, CA, USA. jandersen@buckinstitute.org.; School of Gerontology, USC Leonard Davis, University of Southern California, Los Angeles, CA, USA. jandersen@buckinstitute.org.

Publikováno v: GeroScience [Geroscience] 2023 Apr; Vol. 45 (2), pp. 1237-1245. Date of Electronic Publication: 2022 Aug 26.