Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Arpita Tawani"'
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)
Abstract Small molecule ligands that could stabilize G-quadruplex structure formed at the promoter region of human c-myc oncogene will regulate its expression in cancer cells. Flavonoids, a group of naturally available small molecule, have been known
Externí odkaz:
https://doaj.org/article/d2ba3ee4825e4473966e93502f33a65e
Autor:
Anthony Legrand, Denis Martinez, Axelle Grélard, Melanie Berbon, Estelle Morvan, Arpita Tawani, Antoine Loquet, Sébastien Mongrand, Birgit Habenstein
Publikováno v:
Frontiers in Molecular Biosciences, Vol 6 (2019)
Nanodomains are dynamic membrane subcompartments, enriched in specific lipid, and protein components that act as functional platforms to manage an abundance of cellular processes. The remorin protein of plants is a well-established nanodomain marker
Externí odkaz:
https://doaj.org/article/c18fcf3dc0c44b88afbe23e8f376fca1
Autor:
Arpita Tawani, Amit Kumar
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0131788 (2015)
In humans, neurodegenerative disorders such as Huntington's disease (HD) and many spinocerebellar ataxias (SCAs) have been found to be associated with CAG trinucleotide repeat expansion. An important RNA-mediated mechanism that causes these diseases
Externí odkaz:
https://doaj.org/article/0dd905228edd405b95ee2ce51973b5d2
Publikováno v:
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases. 101
The genome of a micro-organism contains all the information required for its survival inside its host cells. The guanine rich regions of the genome can form stable G-quadruplex structures that act as the regulators of gene expression. Herein, the com
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::83cf39d57f4b3570759388d69950cf81
https://pubmed.ncbi.nlm.nih.gov/35526824
https://pubmed.ncbi.nlm.nih.gov/35526824
Publikováno v:
Infection, Genetics and Evolution. 101:105298
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::03ea2dd71a2d6106199a59da6b11d05c
https://doi.org/10.1016/j.meegid.2022.105298
https://doi.org/10.1016/j.meegid.2022.105298
Autor:
Arpita Tawani, Amit Kumar, Souvik Maiti, Mary Krishna Ekka, Arpita Ghosh, Debojyoti Chakraborty
Publikováno v:
Biochemistry. 58:514-525
Noncoding RNAs are functional RNA molecules that get transcribed from DNA but are not translated into proteins; yet, they can regulate gene expression at transcriptional and post-transcriptional levels. Secondary structures present within these RNAs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f334a13f6cab07ca2ca41e3bc62ba9ab
https://doi.org/10.1021/acs.biochem.8b00880
https://doi.org/10.1021/acs.biochem.8b00880
Autor:
Birgit, Habenstein, Nadia, El Mammeri, James, Tolchard, Gaëlle, Lamon, Arpita, Tawani, Mélanie, Berbon, Antoine, Loquet
Publikováno v:
Current topics in microbiology and immunology. 427
Among the Gram-negative bacterial secretion systems, type III secretion systems (T3SS) possess a unique extracellular molecular apparatus called the needle. This macromolecular protein assembly is a nanometre-size filament formed by the helical arran
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c2e0bbd7b8609cd29bff11e01b63faa3
https://pubmed.ncbi.nlm.nih.gov/31974760
https://pubmed.ncbi.nlm.nih.gov/31974760
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-13 (2019)
Scientific Reports
Scientific Reports
Several G-quadruplex forming motifs have been reported to be highly conserved in the regulatory regions of the genome of different organisms and influence various biological processes like DNA replication, recombination and gene expression. Here, we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0018827fe2f3b01ad35268430453a7b
https://doi.org/10.1038/s41598-018-38400-x
https://doi.org/10.1038/s41598-018-38400-x
Autor:
Prashant Kodgire, Amit Kumar, Neha Jain, Ankit Jaiswal, Uma Shankar, Tarun Kumar Sharma, Subodh Kumar Mishra, Arpita Tawani
The G-quadruplex structure forming motifs have recently emerged as a novel therapeutic drug target in various human pathogens. Herein, we report three highly conserved G-quadruplex motifs (SE-PGQ-1, 2, and3) in genome of all the 412 strains ofSalmone
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::468a6c459fee02d032687a04ec54ec16
https://doi.org/10.1101/357046
https://doi.org/10.1101/357046
Publikováno v:
Database. 2018
High-throughput screening and better understanding of small molecule's structure-activity relationship (SAR) using computational biology techniques have greatly expanded the face of drug discovery process in better discovery of therapeutics for vario
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83b3ea2b0ad92c0bfabf3f5623c8abe2
https://doi.org/10.1093/database/bay082
https://doi.org/10.1093/database/bay082