Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Arpiar Saunders"'
Autor:
Arpiar Saunders, Kee Wui Huang, Cassandra Vondrak, Christina Hughes, Karina Smolyar, Harsha Sen, Adrienne C. Philson, James Nemesh, Alec Wysoker, Seva Kashin, Bernardo L. Sabatini, Steven A. McCarroll
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)
Synaptic connections are critical for brain function but are hard to measure systematically. Here, authors present a method which uses rabies virus barcoding and single-cell RNAseq to parallelize monosynaptic network reconstruction from molecularly-p
Externí odkaz:
https://doaj.org/article/c7dc9db066af4ae5b6945c37c0954d48
Autor:
Adam J Granger, Wengang Wang, Keiramarie Robertson, Mahmoud El-Rifai, Andrea F Zanello, Karina Bistrong, Arpiar Saunders, Brian W Chow, Vicente Nuñez, Miguel Turrero García, Corey C Harwell, Chenghua Gu, Bernardo L Sabatini
Publikováno v:
eLife, Vol 9 (2020)
The mouse cerebral cortex contains neurons that express choline acetyltransferase (ChAT) and are a potential local source of acetylcholine. However, the neurotransmitters released by cortical ChAT+ neurons and their synaptic connectivity are unknown.
Externí odkaz:
https://doaj.org/article/46e08e2f33a545e3a225aa162a807d44
Publikováno v:
PLoS ONE, Vol 11, Iss 2, p e0149798 (2016)
The globus pallidus externus (GP) is a nucleus of the basal ganglia (BG), containing GABAergic projection neurons that arborize widely throughout the BG, thalamus and cortex. Ongoing work seeks to map axonal projection patterns from GP cell types, as
Externí odkaz:
https://doaj.org/article/ad46f5174a3249c292f2b9577ed7eabf
Publikováno v:
eLife, Vol 4 (2015)
Dopamine is released in the striatum during development and impacts the activity of Protein Kinase A (PKA) in striatal spiny projection neurons (SPNs). We examined whether dopaminergic neuromodulation regulates activity-dependent glutamatergic synaps
Externí odkaz:
https://doaj.org/article/7444c64bad2c4ea48ce23ea790e64826
Publikováno v:
eLife, Vol 4 (2015)
Neurotransmitter corelease is emerging as a common theme of central neuromodulatory systems. Though corelease of glutamate or GABA with acetylcholine has been reported within the cholinergic system, the full extent is unknown. To explore synaptic sig
Externí odkaz:
https://doaj.org/article/5709923efe824f8886a64519a9fba23e
Autor:
Alyssa Lutservitz, James Nemesh, Gord Fishell, Alec Wysoker, Benjamin Schuman, Steven A. McCarroll, Kirsten Levandowski, Marta Florio, Victor Tkachev, David Kulp, Richard S. Smith, Arpiar Saunders, Nora Reed, Elizabeth Bien, Monika Burns, Laura Bortolin, Leslie S. Kean, Carolyn Wu, Melissa Goldman, Qiangge Zhang, Christopher A. Walsh, Bernardo Rudy, Heather Zaniewski, Ricardo C.H. del Rosario, Fenna M. Krienen, Robert Machold, Christopher D. Mullally, Guoping Feng, Jessica Lin, Jordane Dimidschstein, Marian Fernandez-Otero, Sabina Berretta
Publikováno v:
Nature
Primates and rodents, which descended from a common ancestor around 90 million years ago1, exhibit profound differences in behaviour and cognitive capacity; the cellular basis for these differences is unknown. Here we use single-nucleus RNA sequencin
Autor:
Steven A. McCarroll, Christina M. Hughes, Alec Wysoker, Karina Smolyar, Harsha Sen, Kee Wui Huang, Arpiar Saunders, Adrienne C. Philson, Seva Kashin, Bernardo L. Sabatini, Cassandra Vondrak, James Nemesh
Brain function depends on forming and maintaining connections between neurons of specific types, ensuring neural function while allowing the plasticity necessary for cellular and behavioral dynamics. However, systematic descriptions of how brain cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::21102ac2673af2c1eea8f1adab24b46d
https://doi.org/10.1101/2021.09.06.459177
https://doi.org/10.1101/2021.09.06.459177
Autor:
Ian R. Wickersham, Steven A. McCarroll, Carter Jones, Nicholas E. Lea, Juliana C. Quay, Arpiar Saunders, Hannah Maisano, Qian Chen, Keith Skaggs, Heather A. Sullivan, Dong Kong, YuanYuan Hou, Vinh Le, Ying Zhang, Tomomi Aida, Soon-Wook Choi, Dheeraj S. Roy, Min Liew, Guoping Feng, Jie Xu
Publikováno v:
Neuron
Neuropsychiatric disorders are often accompanied by cognitive impairments/intellectual disability (ID). It is not clear whether there are converging mechanisms underlying these debilitating impairments. We found that many autism and schizophrenia ris
Autor:
Andrea F Zanello, Corey C. Harwell, Mahmoud El-Rifai, Brian W Chow, Bernardo L. Sabatini, Keiramarie Robertson, Wengang Wang, Miguel Turrero García, Arpiar Saunders, Chenghua Gu, Adam J. Granger, Vicente Nuñez, Karina Bistrong
Publikováno v:
eLife, Vol 9 (2020)
The mouse cerebral cortex contains neurons that express choline acetyltransferase (ChAT) and are a potential local source of acetylcholine. However, the neurotransmitters released by cortical ChAT+ neurons and their synaptic connectivity are unknown.
Autor:
Chenghua Gu, Keiramarie Robertson, Mahmoud El-Rifai, Vicente Nuñez, Bernardo L. Sabatini, Karina Bistrong, Wengang Wang, Arpiar Saunders, Andrea F Zanello, Corey C. Harwell, Miguel Turrero García, Adam J. Granger, Brian W Chow
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1e705ff1121330499f61b687e5b172a4
https://doi.org/10.7554/elife.57749.sa2
https://doi.org/10.7554/elife.57749.sa2