Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Arpana Dutta"'
Publikováno v:
Encyclopedia of Biophysics ISBN: 9783642359439
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3f032e72e2de7a5b2ff11708ed0d7ff8
https://doi.org/10.1007/978-3-642-35943-9_790-1
https://doi.org/10.1007/978-3-642-35943-9_790-1
Autor:
Arpana Dutta, Robert Silvers, Karla Werner, Josef Wachtveitl, Santosh Lakshmi Gande, Judith Klein-Seetharaman, Deep Chatterjee, Frank Scholz, Jochen Stehle, Harald Schwalbe
Publikováno v:
Angewandte Chemie. 126:2110-2116
The mammalian visual dim-light photoreceptor rhodopsin is considered a prototype G protein-coupled receptor. Here, we characterize the kinetics of its light-activation process. Milligram quantities of α,ε-(15)N-labeled tryptophan rhodopsin were pro
Publikováno v:
Scientific Reports
G protein-coupled receptors are a large family of membrane proteins activated by a variety of structurally diverse ligands making them highly adaptable signaling molecules. Despite recent advances in the structural biology of this protein family, the
Publikováno v:
Biochemistry. 49:6317-6328
Little is known about the general folding mechanisms of helical membrane proteins. Unfolded, i.e. non-native states, in particular, have not yet been characterized in detail. Here, we establish conditions under which denatured states of the mammalian
Autor:
Naveena, Yanamala, Arpana, Dutta, Barbara, Beck, Bart, van Vliet, Bart, van Fleet, Kelly, Hay, Ahmad, Yazbak, Rieko, Ishima, Alexander, Doemling, Judith, Klein-Seetharaman
Publikováno v:
Chemical Biology & Drug Design. 75:237-256
Membrane proteins pose problems for the application of NMR-based ligand-screening methods because of the need to maintain the proteins in a membrane mimetic environment such as detergent micelles: they add to the molecular weight of the protein, incr
Autor:
Siddhartha Kar, David Man, Brian I. Carr, Ziv Bar-Joseph, Yanjun Qi, Judith Klein-Seetharaman, Ivan L. Budyak, Harpreet Kaur Dhiman, Kalyan C. Tirupula, Jennifer R. Grandis, Neil E. Bhola, Arpana Dutta
Publikováno v:
PROTEOMICS. 9:5243-5255
Membrane receptor-activated signal transduction pathways are integral to cellular functions and disease mechanisms in humans. Identification of the full set of proteins interacting with membrane receptors by high-throughput experimental means is diff
Autor:
Wayne L. Hubbell, Christian Altenbach, Eric E. Gardner, Naveena Yanamala, Arpana Dutta, Sheryll Mangahas, Judith Klein-Seetharaman
Publikováno v:
Biochemistry
Rhodopsin is a model system for understanding membrane protein folding. Recently, conditions that allow maximally denaturing rhodopsin without causing aggregation have been determined, opening the door to the first structural characterization of dena
Publikováno v:
Biochimica et Biophysica Acta. Bioenergetics
Biochimica et Biophysica Acta (BBA)-Bioenergetics
Biochimica et Biophysica Acta (BBA)-Bioenergetics
Cataloged from PDF version of article. Experimental folding studies of membrane proteins are more challenging than water-soluble proteins because of the higher hydrophobicity content of membrane embedded sequences and the need to provide a hydrophobi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d37a3c45778d008a29420373724b64e
https://hdl.handle.net/11693/38121
https://hdl.handle.net/11693/38121
Publikováno v:
Methods in Molecular Biology ISBN: 9781617794797
Recent years have seen remarkable progress in applying nuclear magnetic resonance (NMR) spectroscopy to proteins that have traditionally been difficult to study due to issues with folding, posttranslational modification, and expression levels or comb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f88b6b6c2d709c0662c9028c1a10dad
https://doi.org/10.1007/978-1-61779-480-3_3
https://doi.org/10.1007/978-1-61779-480-3_3