Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.

Calcium and activity-dependent signaling in the developing cerebral cortex

Autor: Arpana Arjun McKinney, Ralitsa Petrova, Georgia Panagiotakos

Publikováno v: Development (Cambridge, England). 149(17)

Calcium influx can be stimulated by various intra- and extracellular signals to set coordinated gene expression programs into motion. As such, the precise regulation of intracellular calcium represents a nexus between environmental cues and intrinsic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dba3ebdb3892309a7c3432203a023587
https://pubmed.ncbi.nlm.nih.gov/36102617

Effect of Cross-Sex Hormone Therapy on Venous Thromboembolism Risk in Male-to-Female Gender-Affirming Surgery

Autor: Maxwell M Wang, Kassandra E. Zaila, Christos S Haveles, Arpana Arjun, Justine C. Lee

Publikováno v: Annals of plastic surgery. 86(1)

Individuals with gender dysphoria often seek medical interventions, such as hormone treatment and surgery, to live as their identified gender. Cross-sex hormone therapy typically consists of various estrogen formulations which confer varying risks of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1655a4fb4390d50e3fd6b5cfa024051c
https://pubmed.ncbi.nlm.nih.gov/32079810

Aberrant calcium channel splicing drives defects in cortical differentiation in Timothy syndrome

Autor: Sergiu P. Paşca, Georgia Panagiotakos, Christos S Haveles, Thomas Portmann, Ricardo E. Dolmetsch, Anshul Rana, Theo D. Palmer, Arpana Arjun, Ralitsa Petrova

Publikováno v: eLife, Vol 8 (2019)
eLife

The syndromic autism spectrum disorder (ASD) Timothy syndrome (TS) is caused by a point mutation in the alternatively spliced exon 8A of the calcium channel Cav1.2. Using mouse brain and human induced pluripotent stem cells (iPSCs), we provide eviden

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54ac909da48f66912450d22b080d6708
https://elifesciences.org/articles/51037

Amelioration of toxicity in neuronal models of amyotrophic lateral sclerosis by hUPF1

Autor: Arpana Arjun, Dagmar Ringe, Eric J. Huang, Gregory A. Petsko, Yuxi Zhang, Steven Finkbeiner, Daniel Peisach, Xingli Li, Anthony Batarse, Haiyan Qiu, Hilary C. Archbold, Elizabeth M. H. Tank, Shulin Ju, Sami J. Barmada

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America, vol 112, iss 25
Barmada, SJ; Ju, S; Arjun, A; Batarse, A; Archbold, HC; Peisach, D; et al.(2015). Amelioration of toxicity in neuronal models of amyotrophic lateral sclerosis by hUPF1. Proceedings of the National Academy of Sciences of the United States of America, 112(25), 7821-7826. doi: 10.1073/pnas.1509744112. UC San Francisco: Retrieved from: http://www.escholarship.org/uc/item/5dn3b2m6

© 2015, National Academy of Sciences. All rights reserved. Over 30% of patients with amyotrophic lateral sclerosis (ALS) exhibit cognitive deficits indicative of frontotemporal dementia (FTD), suggesting a common pathogenesis for both diseases. Cons

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b41a215b7bf5513f473f2324ad29053
https://escholarship.org/uc/item/5dn3b2m6