Insulin/IGF-1 Signaling Regulates Proteasome Activity through the Deubiquitinating Enzyme UBH-4

Autor: Matilainen, Olli, Arpalahti, Leena, Rantanen, Ville, Hautaniemi, Sampsa, Holmberg, Carina I.

Publikováno v: In Cell Reports 27 June 2013 3(6):1980-1995

The Proteasome-Associated Deubiquitinase UCHL5/UBH-4 in Proteasome Modulation and as a Prognostic Marker in Gastrointestinal Cancers

Autor: Arpalahti, Leena

The ubiquitin-proteasome system (UPS) is the major cellular pathway for controlled protein degradation, and, together with the autophagy-lysosome pathway, it is a central player in maintaining protein homeostasis. The catalytic core of the UPS is the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______1593::73a3aa7233f31b96fc8db003e23f93c3
http://hdl.handle.net/10138/232059

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Proteostasis Dysregulation in Pancreatic Cancer.

Autor: Arpalahti L; Medicum, Department of Biochemistry and Developmental Biology, University of Helsinki, Helsinki, Finland., Haglund C; Research Programs Unit, Translational Cancer Medicine Program, University of Helsinki, Helsinki, Finland.; Department of Surgery, Helsinki University Hospital, University of Helsinki, Helsinki, Finland., Holmberg CI; Medicum, Department of Biochemistry and Developmental Biology, University of Helsinki, Helsinki, Finland. carina.holmberg@helsinki.fi.

Publikováno v: Advances in experimental medicine and biology [Adv Exp Med Biol] 2020; Vol. 1233, pp. 101-115.