Shared heritability and functional enrichment across six solid cancers

Autor: Jiang, Xia, Finucane, Hilary K., Schumacher, Fredrick R., Schmit, Stephanie L., Tyrer, Jonathan P., Han, Younghun, Michailidou, Kyriaki, Lesseur, Corina, Kuchenbaecker, Karoline B., Dennis, Joe, Conti, David V., Casey, Graham, Gaudet, Mia M., Huyghe, Jeroen R., Albanes, Demetrius, Aldrich, Melinda C., Andrew, Angeline S., Andrulis, Irene L., Anton-Culver, Hoda, Antoniou, Antonis C., Antonenkova, Natalia N., Arnold, Susanne M., Aronsen, Kristan J., Arun, Banu K., Bandera, Elisa V., Barkardottir, Rosa B., Barnes, Daniel R., Batra, Jyotsna, Beckmann, Matthias W., Benitez, Javier, Benlloch, Sara, Berchuck, Andrew, Berndt, Sonja I., Bickeboller, Heike, Bien, Stephanie A., Blomqvist, Carl, Boccia, Stefania, Bogdanova, Natalia V., Bojesen, Stig E., Bolla, Manjeet K., Brauch, Hiltrud, Brenner, Hermann, Brenton, James D., Brook, Mark N., Brunet, Joan, Brunnström, Hans, Buchanan, Daniel D., Burwinkel, Barbara, Butzow, Ralf, Cadoni, Gabriella, Caldés, Trinidad, Caligo, Maria A., Campbell, Ian, Campbell, Peter T., Cancel-Tassin, Geraldine, Cannon-Albright, Lisa, Campa, Daniele, Caporaso, Neil, Carvalho, André L., Chan, Andrew T., Chang-Claude, Jenny, Chanock, Stephen J., Chen, Chu, Christiani, David C., Claes, Kathleen B.M., Claessens, Frank, Clements, Judith, Collée, J. Margriet, Correa, Marcia Cruz, Couch, Fergus J., Cox, Angela, Cunningham, Julie M., Cybulski, Cezary, Czene, Kamila, Daly, Mary B., deFazio, Anna, Devilee, Peter, Diez, Orland, Gago-Dominguez, Manuela, Donovan, Jenny L., Dörk, Thilo, Duell, Eric J., Dunning, Alison M., Dwek, Miriam, Eccles, Diana M., Edlund, Christopher K., Edwards, Digna R. Velez, Ellberg, Carolina, Evans, D. Gareth, Fasching, Peter A., Ferris, Robert L., Liloglou, Triantafillos, Figueiredo, Jane C., Fletcher, Olivia, Fortner, Renée T., Fostira, Florentia, Franceschi, Silvia, Friedman, Eitan, Gallinger, Steven J., Ganz, Patricia A., Garber, Judy, García-Sáenz, José A., Gayther, Simon A., Giles, Graham G., Godwin, Andrew K., Goldberg, Mark S., Goldgar, David E., Goode, Ellen L., Goodman, Marc T., Goodman, Gary, Grankvist, Kjell, Greene, Mark H., Grönberg, Henrik, Gronwald, Jacek, Guénel, Pascal, Håkansson, Niclas, Hall, Per, Hamann, Ute, Hamdy, Freddie C., Hamilton, Robert J., Hampe, Jochen, Haugen, Aage, Heitz, Florian, Herrero, Rolando, Hillemanns, Peter, Hoffmeister, Michael, Høgdall, Estrid, Hong, Yun-Chul, Hopper, John L., Houlston, Richard, Hulick, Peter J., Hunter, David J., Huntsman, David G., Idos, Gregory, Imyanitov, Evgeny N., Ingles, Sue Ann, Isaacs, Claudine, Jakubowska, Anna, James, Paul, Jenkins, Mark A., Johansson, Mattias, Johansson, Mikael, John, Esther M., Joshi, Amit D., Kaneva, Radka, Karlan, Beth Y., Kelemen, Linda E., Kuhl, Tabea, Khaw, Kay-Tee, Khusnutdinova, Elza, Kibel, Adam S., Kiemeney, Lambertus A., Kim, Jeri, Kjær, Susanne K., Knight, Julia A., Kogevinas, Manolis, Kote-Jarai, Zsofia, Koutros, Stella, Kristensen, Vessela N., Kupryjanczyk, Jolanta, Lacko, Martin, Lam, Stephan, Lambrechts, Diether, Landi, Maria Teresa, Lazarus, Philip, Le, Nhu D., Lee, Eunjung, Lejbkowicz, Flavio, Lenz, Heinz-Josef, Leslie, Goska, Lessel, Davor, Lester, Jenny, Levine, Douglas A., Li, Li, Li, Christopher I., Lindblom, Annika, Lindor, Noralane M., Liu, Geoffrey, Loupakis, Fotios, Lubinski, Jan, Mæhle, Lovise Olaug, Maier, Christiane, Mannermaa, Arto, Marchand, Loic Le, Margolin, Sara, May, Taymaa, McGuffog, Lesley, Meindl, Alfons, Middha, Pooja, Miller, Austin, Milne, Roger L., MacInnis, Robert J., Modugno, Francesmary, Montagna, Marco, Moreno, Victor, Moysich, Kirsten B., Mucci, Lorelei, Muir, Kenneth, Mulligan, Anna Marie, Nathanson, Katherine L., Neal, David E., Ness, Andrew R., Neuhausen, Susan L., Nevanlinna, Heli, Newcomb, Polly A., Newcomb, Lisa F., Nielsen, Finn Cilius, Nikitina-Zake, Liene, Nordestgaard, Børge G., Nussbaum, Robert L., Offit, Kenneth, Olah, Edith, Olama, Ali Amin Al, Olopade, Olufunmilayo I., Olshan, Andrew F., Olsson, Håkan, Osorio, Ana, Pandha, Hardev, Park, Jong Y., Pashayan, Nora, Parsons, Michael T., Pejovic, Tanja, Penney, Kathryn L., Peters, Wilbert H.M., Phelan, Catherine M., Phipps, Amanda I., Plaseska-Karanfilska, Dijana, Pring, Miranda, Prokofyeva, Darya, Radice, Paolo, Stefansson, Kari, Ramus, Susan J., Raskin, Leon, Rennert, Gad, Rennert, Hedy S., van Rensburg, Elizabeth J., Riggan, Marjorie J., Risch, Harvey A., Risch, Angela, Roobol, Monique J., Rosenstein, Barry S., Rossing, Mary Anne, De Ruyck, Kim, Saloustros, Emmanouil, Sandler, Dale P., Sawyer, Elinor J., Schabath, Matthew B., Schleutker, Johanna, Schmidt, Marjanka K., Setiawan, V. Wendy, Shen, Hongbing, Siegel, Erin M., Sieh, Weiva, Singer, Christian F., Slattery, Marthaa L., Sørensen, Karina Dalsgaard, Southey, Melissa C., Spurdle, Amanda B., Stanford, Janet L., Stevens, Victoria L., Stintzing, Sebastian, Stone, Jennifer, Sundfeldt, Karin, Sutphen, Rebecca, Swerdlow, Anthony J., Tajara, Eloiza H, Tangen, Catherine M., Tardon, Adonina, Taylor, Jack A., Teare, M. Dawn, Teixeira, Manuel, Terry, Mary Beth, Terry, Kathryn L., Thibodeau, Stephen N., Thomassen, Mads, Bjørge, Line, Tischkowitz, Marc, Toland, Amanda E., Torres, Diana, Townsend, Paul A., Travis, Ruth C., Tung, Nadine, Tworoger, Shelley S., Ulrich, Cornelia M., Usmani, Nawaid, Vachon, Celine M., Van Nieuwenhuysen, Els, Vega, Ana, Aguado-Barrera, Miguel Elias, Wang, Qin, Webb, Penelope M., Weinberg, Clarice R., Weinstein, Stephanie, Weissler, Mark C., Weitzel, Jeffrey N., West, Catharine M.L., White, Emily, Whittemore, Alice S., Wichmann, H.-Erich, Wiklund, Fredrik, Winqvist, Robert, Wolk, Alicja, Woll, Penella, Woods, Michael, Wu, Anna H., Wu, Xifeng, Yannoukakos, Drakoulis, Zheng, Wei, Zienolddiny, Shanbeh, Ziogas, Argyrios, Zorn, Kristin K., Lane, Jacqueline M., Saxena, Richa, Thomas, Duncan, Hung, Rayjean J., Diergaarde, Brenda, McKay, James, Peters, Ulrike, Hsu, Li, García-Closas, Montserrat, Eeles, Rosalind A., Chenevix-Trench, Georgia, Brennan, Paul J., Haiman, Christopher A., Simard, Jacques, Easton, Douglas F., Gruber, Stephen B., Pharoah, Paul D.P., Price, Alkes L., Pasaniuc, Bogdan, Amos, Christopher I., Kraft, Peter, Lindström, Sara

Publikováno v: Jiang, Xia Finucane, Hilary K. Schumacher, Fredrick R. Schmit, Stephanie L. Tyrer, Jonathan P. Han, Younghun Michailidou, Kyriaki Lesseur, Corina Kuchenbaecker, Karoline B. Dennis, Joe Conti, David V. Casey, Graham Gaudet, Mia M. Huyghe, Jeroen R. Albanes, Demetrius Aldrich, Melinda C. Andrew, Angeline S. Andrulis, Irene L. Anton-Culver, Hoda Antoniou, Antonis C. Antonenkova, Natalia N. Arnold, Susanne M. Aronsen, Kristan J. Arun, Banu K. Bandera, Elisa V. Barkardottir, Rosa B. Barnes, Daniel R. Batra, Jyotsna Beckmann, Matthias W. Benitez, Javier Benlloch, Sara Berchuck, Andrew Berndt, Sonja I. Bickeboller, Heike Bien, Stephanie A. Blomqvist, Carl Boccia, Stefania Bogdanova, Natalia V. Bojesen, Stig E. Bolla, Manjeet K. Brauch, Hiltrud Brenner, Hermann Brenton, James D. Brook, Mark N. Brunet, Joan Brunnström, Hans Buchanan, Daniel D. Burwinkel, Barbara Butzow, Ralf Cadoni, Gabriella Caldés, Trinidad Caligo, Maria A. Campbell, Ian Campbell, Peter T. Cancel-Tassin, Geraldine Cannon-Albright, Lisa Campa, Daniele Caporaso, Neil Carvalho, André L. Chan, Andrew T. Chang-Claude, Jenny Chanock, Stephen J. Chen, Chu Christiani, David C. Claes, Kathleen B.M. Claessens, Frank Clements, Judith Collée, J. Margriet Correa, Marcia Cruz Couch, Fergus J. Cox, Angela Cunningham, Julie M. Cybulski, Cezary Czene, Kamila Daly, Mary B. deFazio, Anna Devilee, Peter Diez, Orland Gago-Dominguez, Manuela Donovan, Jenny L. Dörk, Thilo Duell, Eric J. Dunning, Alison M. Dwek, Miriam Eccles, Diana M. Edlund, Christopher K. Edwards, Digna R. Velez Ellberg, Carolina Evans, D. Gareth Fasching, Peter A. Ferris, Robert L. Liloglou, Triantafillos Figueiredo, Jane C. Fletcher, Olivia Fortner, Renée T. Fostira, Florentia Franceschi, Silvia Friedman, Eitan Gallinger, Steven J. Ganz, Patricia A. Garber, Judy García-Sáenz, José A. Gayther, Simon A. Giles, Graham G. Godwin, Andrew K. Goldberg, Mark S. Goldgar, David E. Goode, Ellen L. Goodman, Marc T. Goodman, Gary Grankvist, Kjell Greene, Mark H. Grönberg, Henrik Gronwald, Jacek Guénel, Pascal Håkansson, Niclas Hall, Per Hamann, Ute Hamdy, Freddie C. Hamilton, Robert J. Hampe, Jochen Haugen, Aage Heitz, Florian Herrero, Rolando Hillemanns, Peter Hoffmeister, Michael Høgdall, Estrid Hong, Yun-Chul Hopper, John L. Houlston, Richard Hulick, Peter J. Hunter, David J. Huntsman, David G. Idos, Gregory Imyanitov, Evgeny N. Ingles, Sue Ann Isaacs, Claudine Jakubowska, Anna James, Paul Jenkins, Mark A. Johansson, Mattias Johansson, Mikael John, Esther M. Joshi, Amit D. Kaneva, Radka Karlan, Beth Y. Kelemen, Linda E. Kuhl, Tabea Khaw, Kay-Tee Khusnutdinova, Elza Kibel, Adam S. Kiemeney, Lambertus A. Kim, Jeri Kjær, Susanne K. Knight, Julia A. Kogevinas, Manolis Kote-Jarai, Zsofia Koutros, Stella Kristensen, Vessela N. Kupryjanczyk, Jolanta Lacko, Martin Lam, Stephan Lambrechts, Diether Landi, Maria Teresa Lazarus, Philip Le, Nhu D. Lee, Eunjung Lejbkowicz, Flavio Lenz, Heinz-Josef Leslie, Goska Lessel, Davor Lester, Jenny Levine, Douglas A. Li, Li Li, Christopher I. Lindblom, Annika Lindor, Noralane M. Liu, Geoffrey Loupakis, Fotios Lubinski, Jan Mæhle, Lovise Olaug Maier, Christiane Mannermaa, Arto Marchand, Loic Le Margolin, Sara May, Taymaa McGuffog, Lesley Meindl, Alfons Middha, Pooja Miller, Austin Milne, Roger L. MacInnis, Robert J. Modugno, Francesmary Montagna, Marco Moreno, Victor Moysich, Kirsten B. Mucci, Lorelei Muir, Kenneth Mulligan, Anna Marie Nathanson, Katherine L. Neal, David E. Ness, Andrew R. Neuhausen, Susan L. Nevanlinna, Heli Newcomb, Polly A. Newcomb, Lisa F. Nielsen, Finn Cilius Nikitina-Zake, Liene Nordestgaard, Børge G. Nussbaum, Robert L. Offit, Kenneth Olah, Edith Olama, Ali Amin Al Olopade, Olufunmilayo I. Olshan, Andrew F. Olsson, Håkan Osorio, Ana Pandha, Hardev Park, Jong Y. Pashayan, Nora Parsons, Michael T. Pejovic, Tanja Penney, Kathryn L. Peters, Wilbert H.M. Phelan, Catherine M. Phipps, Amanda I. Plaseska-Karanfilska, Dijana Pring, Miranda Prokofyeva, Darya Radice, Paolo Stefansson, Kari Ramus, Susan J. Raskin, Leon Rennert, Gad Rennert, Hedy S. van Rensburg, Elizabeth J. Riggan, Marjorie J. Risch, Harvey A. Risch, Angela Roobol, Monique J. Rosenstein, Barry S. Rossing, Mary Anne De Ruyck, Kim Saloustros, Emmanouil Sandler, Dale P. Sawyer, Elinor J. Schabath, Matthew B. Schleutker, Johanna Schmidt, Marjanka K. Setiawan, V. Wendy Shen, Hongbing Siegel, Erin M. Sieh, Weiva Singer, Christian F. Slattery, Marthaa L. Sørensen, Karina Dalsgaard Southey, Melissa C. Spurdle, Amanda B. Stanford, Janet L. Stevens, Victoria L. Stintzing, Sebastian Stone, Jennifer Sundfeldt, Karin Sutphen, Rebecca Swerdlow, Anthony J. Tajara, Eloiza H Tangen, Catherine M. Tardon, Adonina Taylor, Jack A. Teare, M. Dawn Teixeira, Manuel Terry, Mary Beth Terry, Kathryn L. Thibodeau, Stephen N. Thomassen, Mads Bjørge, Line Tischkowitz, Marc Toland, Amanda E. Torres, Diana Townsend, Paul A. Travis, Ruth C. Tung, Nadine Tworoger, Shelley S. Ulrich, Cornelia M. Usmani, Nawaid Vachon, Celine M. Van Nieuwenhuysen, Els Vega, Ana Aguado-Barrera, Miguel Elias Wang, Qin Webb, Penelope M. Weinberg, Clarice R. Weinstein, Stephanie Weissler, Mark C. Weitzel, Jeffrey N. West, Catharine M.L. White, Emily Whittemore, Alice S. Wichmann, H.-Erich Wiklund, Fredrik Winqvist, Robert Wolk, Alicja Woll, Penella Woods, Michael Wu, Anna H. Wu, Xifeng Yannoukakos, Drakoulis Zheng, Wei Zienolddiny, Shanbeh Ziogas, Argyrios Zorn, Kristin K. Lane, Jacqueline M. Saxena, Richa Thomas, Duncan Hung, Rayjean J. Diergaarde, Brenda McKay, James Peters, Ulrike Hsu, Li García-Closas, Montserrat Eeles, Rosalind A. Chenevix-Trench, Georgia Brennan, Paul J. Haiman, Christopher A. Simard, Jacques Easton, Douglas F. Gruber, Stephen B. Pharoah, Paul D.P. Price, Alkes L. Pasaniuc, Bogdan Amos, Christopher I. Kraft, Peter Lindström, Sara . Shared heritability and functional enrichment across six solid cancers. Nature Communications. 2019, 10:431, 1-23
Nature Communications

Externí odkaz: http://hdl.handle.net/10852/75034
https://www.duo.uio.no/bitstream/handle/10852/75034/1/s41467-018-08054-4.pdf