Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Aron T. Goldberg"'
Autor:
C.Allyson Walker, Francis G. Spinale, Aron T. Goldberg, Fred A. Crawford, Jennifer W. Hendrick, David J. Fary, Daniel K. Almany, Jennifer Davis, Cassandra Joffs
Publikováno v:
The Journal of Thoracic and Cardiovascular Surgery. 122:365-370
Background: The bioactive peptide endothelin-1 is elevated during and after cardiopulmonary bypass and exerts cardiovascular effects through its 2 receptor subtypes, endothelin-1A and endothelin-1B. Increased endothelin-1A receptor stimulation after
Autor:
R. Stephen Krombach, James H. McElmuray, David M. Gay, Mark J. Clair, Rupak Mukherjee, Aron T. Goldberg, Simona C. Baicu, Francis G. Spinale
Publikováno v:
Journal of Cardiovascular Pharmacology and Therapeutics. 5:291-299
Background: Past studies have demonstrated that exogenous bradykinin (BK) causes vasodilation and increases coronary blood flow, effects that may be beneficial in the setting of cardiac disease states. An important pathway for BK degradation is throu
Autor:
C.Allyson Walker, Simona C. Baicu, Colin E. Widener, David J. Fary, Adviye Ergul, Aron T. Goldberg, Fred A. Crawford, Francis G. Spinale, Daniel K. Almany
Publikováno v:
The Journal of Thoracic and Cardiovascular Surgery. 120(5):864-871
Objective: Increased systemic levels of the bioactive peptide endothelin 1 during and after cardioplegic arrest and cardiopulmonary bypass have been well documented. However, endothelin 1 is synthesized locally, and therefore myocardial endothelin 1
Autor:
Simona C. Baicu, Adviye Ergul, C.Allyson Walker, Aron T. Goldberg, Francis G. Spinale, Mary K. King, Jennifer W. Hendrick
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 278:H2050-H2056
Increased plasma levels of endothelin-1 (ET-1) have been identified in congestive heart failure (CHF), but local myocardial interstitial ET-1 levels and the relation to determinants of ET-1 synthesis remain to be defined. Accordingly, myocardial inte
Autor:
James L. Zellner, Aron T. Goldberg, Brian R. Bond, Rupak Mukherjee, Fred A. Crawford, Francis G. Spinale, R.Brent New
Publikováno v:
The Annals of Thoracic Surgery. 69:711-715
Increased synthesis and release of the potent bioactive peptide endothelin-1 (ET-1) occurs during and after cardiac surgery. However, the cellular and molecular basis for the effects of ET-1 on human left ventricular (LV) myocyte contractility remain
Autor:
Francis G. Spinale, Simona C. Baicu, Jeff A. Sample, Aron T. Goldberg, R.Stephen Krombach, Mary K. King, Marc deGasparo, Marlina M. Multani, Cassandra Joffs, Jennifer W. Hendrick
Publikováno v:
Journal of cardiovascular pharmacology and therapeutics. 6(4)
Background: The present study examined the effects of acute angiotensin-converting enzyme inhibition (ACEI), AT, receptor blockade (AT, block), or combined treatment on in vitro and in vivo bradykinin (BK) levels. Methods: BK levels were measured in
Autor:
Cassandra Joffs, Jeffrey A. Sample, Aron T. Goldberg, Francis G. Spinale, Rupak Mukherjee, Jennifer R. Holder, Therese Patterson, Jennifer Davis, Glenn J. Smits, Jennifer W. Hendrick, David G. Lucas
Publikováno v:
Journal of cardiovascular pharmacology. 38(4)
The adenosine subtype 1 (A1) receptor, which may influence cardiac function and modulate renal function, may have particular relevance in congestive heart failure (CHF). However, the effects of A1 receptor inhibition in the setting of CHF are poorly
Autor:
Aron T. Goldberg, C.Allyson Walker, Fred A. Crawford, Jennifer W. Hendrick, Daniel K. Almany, Cassandra Joffs, Francis G. Spinale, David J. Fary, Jennifer Davis
Publikováno v:
Journal of the American College of Surgeons. 191:S10