Influenza virus replication in cardiomyocytes drives heart dysfunction and fibrosis.

Autor: Kenney AD; Department of Microbial Infection and Immunity, The Ohio State University, Columbus, OH, USA.; Infectious Diseases Institute, Viruses and Emerging Pathogens Program, The Ohio State University, Columbus, OH, USA., Aron SL; Department of Microbiology and Immunology, The University of Minnesota, Minneapolis, MN, USA., Gilbert C; Department of Microbiology and Immunology, The University of Minnesota, Minneapolis, MN, USA., Kumar N; Department of Microbial Infection and Immunity, The Ohio State University, Columbus, OH, USA., Chen P; Department of Physiology and Cell Biology, The Ohio State University, Columbus, OH, USA., Eddy A; Department of Microbial Infection and Immunity, The Ohio State University, Columbus, OH, USA.; Infectious Diseases Institute, Viruses and Emerging Pathogens Program, The Ohio State University, Columbus, OH, USA., Zhang L; Department of Microbial Infection and Immunity, The Ohio State University, Columbus, OH, USA.; Infectious Diseases Institute, Viruses and Emerging Pathogens Program, The Ohio State University, Columbus, OH, USA., Zani A; Department of Microbial Infection and Immunity, The Ohio State University, Columbus, OH, USA.; Infectious Diseases Institute, Viruses and Emerging Pathogens Program, The Ohio State University, Columbus, OH, USA., Vargas-Maldonado N; Department of Microbial Infection and Immunity, The Ohio State University, Columbus, OH, USA., Speaks S; Department of Microbial Infection and Immunity, The Ohio State University, Columbus, OH, USA., Kawahara J; Department of Microbial Infection and Immunity, The Ohio State University, Columbus, OH, USA.; Infectious Diseases Institute, Viruses and Emerging Pathogens Program, The Ohio State University, Columbus, OH, USA., Denz PJ; Department of Microbial Infection and Immunity, The Ohio State University, Columbus, OH, USA.; Infectious Diseases Institute, Viruses and Emerging Pathogens Program, The Ohio State University, Columbus, OH, USA., Dorn L; Department of Physiology and Cell Biology, The Ohio State University, Columbus, OH, USA., Accornero F; Department of Physiology and Cell Biology, The Ohio State University, Columbus, OH, USA., Ma J; Department of Surgery, The Ohio State University, Columbus, OH, USA., Zhu H; Department of Surgery, The Ohio State University, Columbus, OH, USA., Rajaram MVS; Department of Microbial Infection and Immunity, The Ohio State University, Columbus, OH, USA., Cai C; Department of Surgery, The Ohio State University, Columbus, OH, USA., Langlois RA; Department of Microbiology and Immunology, The University of Minnesota, Minneapolis, MN, USA., Yount JS; Department of Microbial Infection and Immunity, The Ohio State University, Columbus, OH, USA.; Infectious Diseases Institute, Viruses and Emerging Pathogens Program, The Ohio State University, Columbus, OH, USA.

Publikováno v: Science advances [Sci Adv] 2022 May 13; Vol. 8 (19), pp. eabm5371. Date of Electronic Publication: 2022 May 11.

Engineered Small-Molecule Control of Influenza A Virus Replication.

Autor: Fay EJ; Biochemistry, Molecular Biology, and Biophysics Graduate Program, University of Minnesota, Minneapolis, Minnesota, USA.; Center for Immunology, University of Minnesota Department of Microbiology and Immunology, University of Minnesota, Minneapolis, Minnesota, USA., Aron SL; Center for Immunology, University of Minnesota Department of Microbiology and Immunology, University of Minnesota, Minneapolis, Minnesota, USA.; Department of Microbiology and Immunology, University of Minnesota, Minneapolis, Minnesota, USA., Stone IA; Center for Immunology, University of Minnesota Department of Microbiology and Immunology, University of Minnesota, Minneapolis, Minnesota, USA.; Department of Microbiology and Immunology, University of Minnesota, Minneapolis, Minnesota, USA., Waring BM; Center for Immunology, University of Minnesota Department of Microbiology and Immunology, University of Minnesota, Minneapolis, Minnesota, USA.; Department of Microbiology and Immunology, University of Minnesota, Minneapolis, Minnesota, USA., Plemper RK; Institute for Biomedical Sciences, Georgia State University, Atlanta, Georgia, USA., Langlois RA; Biochemistry, Molecular Biology, and Biophysics Graduate Program, University of Minnesota, Minneapolis, Minnesota, USA langlois@umn.edu.; Center for Immunology, University of Minnesota Department of Microbiology and Immunology, University of Minnesota, Minneapolis, Minnesota, USA.; Department of Microbiology and Immunology, University of Minnesota, Minneapolis, Minnesota, USA.

Publikováno v: Journal of virology [J Virol] 2018 Dec 10; Vol. 93 (1). Date of Electronic Publication: 2018 Dec 10 (Print Publication: 2019).

FBXL19 in endothelial cells protects the heart from influenza A infection by enhancing antiviral immunity and reducing cellular senescence programs.

Autor: Xia, Boyu, Chen, Huilong, Taleb, Sarah J., Xi, Xiaoqing, Shaheen, Nargis, Baoyinna, Boina, Soni, Sourabh, Mebratu, Yohannes A., Yount, Jacob S., Zhao, Jing, Zhao, Yutong

Publikováno v: American Journal of Physiology: Heart & Circulatory Physiology; Oct2024, Vol. 327 Issue 4, pH937-H946, 10p

Characterization of influenza A virus induced transposons reveals a subgroup of transposons likely possessing the regulatory role as eRNAs.

Autor: Shen, Steven S.^1,2 (AUTHOR) shens@umn.edu, Nanda, Hezkiel¹ (AUTHOR), Aliferis, Constantin¹ (AUTHOR), Langlois, Ryan A.³ (AUTHOR)

Publikováno v: Scientific Reports. 2/9/2022, Vol. 12 Issue 1, p1-12. 12p.

Long-term surviving influenza infected cells evade CD8⁺ T cell mediated clearance.

Autor: Fiege, Jessica K.¹, Stone, Ian A.¹, Dumm, Rebekah E.², Waring, Barbara M.¹, Fife, Brian T.³, Agudo, Judith⁴, Brown, Brian D.⁴, Heaton, Nicholas S.², Langlois, Ryan A.¹ langlois@umn.edu

Publikováno v: PLoS Pathogens. 9/26/2019, Vol. 15 Issue 9, p1-19. 19p.