Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Aron Geurts"'
Autor:
Marek Lenarczyk, Ammar J. Alsheikh, Eric P. Cohen, Dörthe Schaue, Amy Kronenberg, Aron Geurts, Slade Klawikowski, David Mattson, John E. Baker
Publikováno v:
Toxics, Vol 11, Iss 2, p 183 (2023)
In the original publication [...]
Externí odkaz:
https://doaj.org/article/e928f94cf35b436cb456234815704071
Autor:
Marek Lenarczyk, Ammar J. Alsheikh, Eric P. Cohen, Dörthe Schaue, Amy Kronenberg, Aron Geurts, Slade Klawikowski, David Mattson, John E. Baker
Publikováno v:
Toxics, Vol 10, Iss 12, p 797 (2022)
Heart disease is a significant adverse event caused by radiotherapy for some cancers. Identifying the origins of radiogenic heart disease will allow therapies to be developed. Previous studies showed non-targeted effects manifest as fibrosis in the n
Externí odkaz:
https://doaj.org/article/87743c999d43437dbce41acadb8aacf4
Autor:
Karima Ait-Aissa, James S. Heisner, Laura E. Norwood Toro, Dennis Bruemmer, Genevieve Doyon, Leanne Harmann, Aron Geurts, Amadou K. S. Camara, Andreas M. Beyer
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 6 (2019)
Introduction: Elevated levels of mitochondrial reactive oxygen species (ROS) contribute to the development of numerous cardiovascular diseases. TERT, the catalytic subunit of telomerase, has been shown to translocate to mitochondria to suppress ROS w
Externí odkaz:
https://doaj.org/article/cfdee70ad42f4741b2cae97c0374935a
Autor:
Darius Balciunas, Kirk J Wangensteen, Andrew Wilber, Jason Bell, Aron Geurts, Sridhar Sivasubbu, Xin Wang, Perry B Hackett, David A Largaespada, R Scott McIvor, Stephen C Ekker
Publikováno v:
PLoS Genetics, Vol 2, Iss 11, p e169 (2006)
Viruses and transposons are efficient tools for permanently delivering foreign DNA into vertebrate genomes but exhibit diminished activity when cargo exceeds 8 kilobases (kb). This size restriction limits their molecular genetic and biotechnological
Externí odkaz:
https://doaj.org/article/75fbcc48e7b2480297232ff3a0109db0
Autor:
Evan M. Hess, Sara N. Kassel, Gregory Simandl, Nicholas Raddatz, Brian Maunze, Matthew M. Hurley, Michael Grzybowski, Jason Klotz, Aron Geurts, Qing-Song Liu, SuJean Choi, Robert C. Twining, David A. Baker
Publikováno v:
The Journal of Neuroscience. 43:2349-2361
The importance of neuronal glutamate to synaptic transmission throughout the brain illustrates the immense therapeutic potential and safety risks of targeting this system. Astrocytes also release glutamate, the clinical relevance of which is unknown
Autor:
Alexandria Szalanczy, Mackenzie Fitzpatrick, Trangdai Bui, Christina Dyson, Seth Eller, Gina Giorgio, Emily Goff, Julia Landry, Christina Scott, Osborne Seshie, Michael Grzybowski, Jason Klotz, Aron Geurts, Eva Redei, Jeff Weiner, Leah Solberg Woods
Publikováno v:
Physiology. 38
While obesity is an increasingly prevalent disease, genetic susceptibility is poorly understood and more research is sorely needed. Our lab has sought to confirm Keratinocyte-associated protein 3 ( Krtcap3) as a novel adiposity gene and characterize
Autor:
Melinda Dwinell, Akiko Takizawa, Lynn Malloy, Monika Tutaj, Rebecca Schilling, Aron Geurts, Anne Kwitek
Publikováno v:
Physiology. 38
Rats are a major model for studying complex disease mechanisms, behavioral phenotypes, environmental factors, and for drug development and discovery. Inbred rat strains control for genetic background and allow for repeated, reproducible molecular, ce
Autor:
Mark Vanden Avond, Michael Grzybowksi, Theresa Kurth, Andrew Greene, Mingyu Liang, Allen Cowley, Aron Geurts
Publikováno v:
Physiology. 38
Hypertension is the leading risk factor for cardiovascular disease and impacts one in three adults globally. One genetic mechanism that may affect blood pressure regulation and alter hypertension risk in the general population is the disruption of ch
Autor:
Tristan V de Jong, Yanchao Pan, Pasi Rastas, Daniel Munro, Monika Tutaj, Huda Akil, Chris Benner, Apurva S Chitre, William Chow, Vincenza Colonna, Clifton L Dalgard, Wendy M Demos, Peter A Doris, Erik Garrison, Aron Geurts, Hakan M Gunturkun, Victor Guryev, Thibaut Hourlier, Kerstin Howe, Jun Huang, Ted Kalbfleisch, Panjun Kim, Ling Li, Spencer Mahaffey, Fergal J Martin, Pejman Mohammadi, Ayse Bilge Ozel, Oksana Polesskaya, Michal Pravenec, Pjotr Prins, Jonathan Sebat, Jennifer R Smith, Leah C Solberg Woods, Boris Tabakoff, Alan Tracey, Marcela Uliano-Silva, Flavia Villani, Hongyang Wang, Burt M Sharp, Francesca Telese, Zhihua Jiang, Laura Saba, Xusheng Wang, Terence D Murphy, Abraham A Palmer, Anne E Kwitek, Melinda (Mindy) R Dwinell, Robert W Williams, Jun Z Li, Hao Chen
For over a decade, a large research community has relied on a flawed reference assembly of the genome ofRattus norvegicusknown as Rnor_6.0. The seventh assembly of the rat reference genome4mRatBN7.2, based on the inbred Brown Norway rat, corrects num
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::861340d72a1519c031afadb54233c22a
https://doi.org/10.1101/2023.04.13.536694
https://doi.org/10.1101/2023.04.13.536694
Publikováno v:
The FASEB Journal. 36