Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Aroma Agape Gopalai"'
Autor:
Aroma Agape Gopalai, Jia Lun Lim, Hui‐Hua Li, Yi Zhao, Thien Thien Lim, Gaik B. Eow, Santhi Puvanarajah, Shanthi Viswanathan, Mohamed Ibrahim Norlinah, Zariah Abdul Aziz, Soo Kun Lim, Chong Tin Tan, Ai Huey Tan, Shen‐Yang Lim, Eng‐King Tan, Azlina Ahmad Annuar
Publikováno v:
Molecular Genetics & Genomic Medicine, Vol 7, Iss 11, Pp n/a-n/a (2019)
Abstract Background The LRRK2 gene is associated with Parkinson's disease (PD) as a number of mutations within the gene have been shown to be susceptibility factors. Studies on various global populations have determined that mutations such as G2019S,
Externí odkaz:
https://doaj.org/article/2cdb4bd6a8f34f8a95f5ee225dbb99a2
Autor:
Thien Thien Lim, Azlina Ahmad-Annuar, Soo Kun Lim, Wee Kooi Cheah, Yi Wen Tay, Tzi Shin Toh, Khairul Azmi Ibrahim, Ai Huey Tan, Yuganthini Vijayanathan, Irene Looi, Santhi Datuk Puvanarajah, Shanthi Viswanathan, Jia Lun Lim, Eng-King Tan, Gaik Bee Eow, Ebonne Yulin Ng, Aroma Agape Gopalai, Shen-Yang Lim, Zariah Abdul-Aziz, Ping Chong Bee
BackgroundGenome-wide association studies (GWAS) have shown that variants in the 3-methylcrotonyl-CoA carboxylase (MCCC1)/lysosome-associated membrane protein 3 (LAMP3) loci (rs10513789, rs12637471, rs12493050) reduce the risk of Parkinson’s diseas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf5333218397f35d1e757335d719311c
https://zenodo.org/record/4527827
https://zenodo.org/record/4527827
Autor:
Chong Tin Tan, Ai Huey Tan, Gaik Bee Eow, Azlina Ahmad Annuar, Zariah Abdul Aziz, Shanthi Viswanathan, Shen-Yang Lim, Aroma Agape Gopalai, Yi Zhao, Thien Thien Lim, Soo Kun Lim, Huihua Li, Jia Lun Lim, Mohamed Ibrahim Norlinah, Eng-King Tan, Santhi Datuk Puvanarajah
Publikováno v:
Molecular Genetics & Genomic Medicine, Vol 7, Iss 11, Pp n/a-n/a (2019)
Molecular Genetics & Genomic Medicine
Molecular Genetics & Genomic Medicine
Background The LRRK2 gene is associated with Parkinson's disease (PD) as a number of mutations within the gene have been shown to be susceptibility factors. Studies on various global populations have determined that mutations such as G2019S, G2385R,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be9d087d2b9621f772bd203619a705be
https://doaj.org/article/2cdb4bd6a8f34f8a95f5ee225dbb99a2
https://doaj.org/article/2cdb4bd6a8f34f8a95f5ee225dbb99a2
Autor:
Aroma Agape Gopalai, Shen Yang Lim, Zariah Abdul Aziz, Soo Kun Lim, Li Ping Tan, Yip Boon Chong, Chong Tin Tan, Santhi Puvanarajah, Shanti Viswanathan, Rishikesan Kuppusamy, Ai Huey Tan, Thien Thien Lim, Gaik Bee Eow, Mohamed Ibrahim Norlinah, Hui Hua Li, Yi Zhao, Azlina Ahmad-Annuar
Publikováno v:
Annals of the Academy of Medicine, Singapore. 42:237-240
Introduction: The G2385R and R1628P LRRK2 gene variants have been associated with an increased risk of Parkinson’s disease (PD) in the Asian population. Recently, a new LRRK2 gene variant, A419V, was reported to be a third risk variant for PD in As
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::59798e54fc24942597e135783596338b
https://doi.org/10.47102/annals-acadmedsg.v42n5p237
https://doi.org/10.47102/annals-acadmedsg.v42n5p237
Autor:
Eng-King Tan, Li-Ping Tan, Wing Lok Au, Huihua Li, Yi Zhao, Azlina Ahmad-Annuar, Aroma Agape Gopalai, Soo Kun Lim, Norlinah Mohamed Ibrahim, Shen-Yang Lim, Kumar M. Prakash, L. C S Tan, E. W L Teng, Yip Boon Chong
Publikováno v:
Clinical Genetics. 84:501-504
A variant (rs3129882) in the genome-wide association study (GWAS)-linked variant [in the human leukocyte antigen (HLA) gene region] has been reported to associate with an increased risk of Parkinson's disease (PD) in Caucasian population. Studies amo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4371017e91e197e6def0a93ee7182703
https://doi.org/10.1111/cge.12024
https://doi.org/10.1111/cge.12024
Autor:
Yi Zhao, Zariah Abdul Aziz, Viswanathan Shanthi, Puvanarajah Santhi, Gaik Bee Eow, Chong Tin Tan, Thien T hien Lim, Ai Huey Tan, Mohamed Ibrahim Norlinah, Aroma Agape Gopalai, Eng-King Tan, Azlina Ahmad-Annuar, Huihua Li, Soo Kun Lim, Shen-Yang Lim
Publikováno v:
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics. 171(6)
PARK16 was identified as a risk factor for Parkinson's disease in a Japanese cohort; however, subsequent studies in the other populations including the Chinese, European, Caucasian, and Chilean have shown a protective role instead. To investigate thi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::169734a7992b851195a72e9e78a31d09
https://pubmed.ncbi.nlm.nih.gov/27174169
https://pubmed.ncbi.nlm.nih.gov/27174169
Autor:
Gaik Bee Eow, Yi Zhao, Thien T hien Lim, Yip B oon Chong, Shelisa Tey, Eng-King Tan, Shanthi Viswanathan, Zariah Abdul Aziz, Azlina Ahmad-Annuar, Chong T in Tan, Aroma Agape Gopalai, Santhi Datuk Puvanarajah, Ai H uey Tan, Norlinah Mohamed Ibrahim, Jing Y i Chua, Irene Looi, Li P ing Tan, Soo K un Lim, Shen-Yang Lim
Publikováno v:
BioMed Research International
BioMed Research International, Vol 2014 (2014)
BioMed Research International, Vol 2014 (2014)
TheLRRK2gene has been associated with both familial and sporadic forms of Parkinson’s disease (PD). The G2019S variant is commonly found in North African Arab and Caucasian PD patients, but this locus is monomorphic in Asians. The G2385R and R1628P
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3aa9540bfdf8703cc0346e8b58e682a9
https://pubmed.ncbi.nlm.nih.gov/25243190
https://pubmed.ncbi.nlm.nih.gov/25243190