Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Arogya, Khadka"'
Autor:
Alissa Muller, Jack Sullivan, Wibke Schwarzer, Mantian Wang, Cindy Park-Windhol, Beryll Klingler, Jane Matsell, Simon Hostettler, Patricia Galliker, Mert Duman, Yanyan Hou, Pierre Balmer, Tamás Virág, Luis Alberto Barrera, Quan Xu, Dániel Péter Magda, Ferenc Kilin, Arogya Khadka, Mathieu Quinodoz, Pascal W. Hasler, Pierre-Henri Moreau, Lyne Fellmann, Thierry Azoulay, Marco Cattaneo, Simone Picelli, Alice Grison, Cameron S. Cowan, Lucas Janeschitz-Kriegl, Ákos Kusnyerik, Magdalena Renner, Zoltán Zsolt Nagy, Arnold Szabó, Carlo Rivolta, Hendrik P.N. Scholl, David Bryson, Giuseppe Ciaramella, Botond Roska, Bence György
Stargardt disease is a currently untreatable, inherited neurodegenerative disease that leads to macular degeneration and blindness due to loss-of-function mutations in theABCA4gene. We have designed a dual adeno-associated viral vector split-intein a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bd497ac7466dc48e5713f90aa2177981
https://doi.org/10.1101/2023.04.17.535579
https://doi.org/10.1101/2023.04.17.535579
Autor:
Magali Saint-Geniez, Zoltan Arany, Arogya Khadka, Daniel Diaz-Aguilar, Glenn C. Rowe, Jared Iacovelli, Carrie Spencer
Publikováno v:
Investigative Ophthalmology & Visual Science
Purpose Oxidative stress and metabolic dysregulation of the RPE have been implicated in AMD; however, the molecular regulation of RPE metabolism remains unclear. The transcriptional coactivator, peroxisome proliferator-activated receptor-gamma coacti
Publikováno v:
The FASEB Journal. 29
Age-related macular degeneration (AMD) is the leading cause of blindness in the elderly population of industrialized countries. AMD is thought to occur, at least in part, from oxidative damage to t...
Autor:
Maximilian J, Gerhardt, Joseph A, Marsh, Margaux, Morrison, Andrius, Kazlauskas, Arogya, Khadka, Stephan, Rosenkranz, Margaret M, DeAngelis, Magali, Saint-Geniez, Sarah Melissa P, Jacobo
Publikováno v:
Journal of molecular cell biology
J Mol Cell Biol
J Mol Cell Biol
High temperature requirement A1 (HtrA1) belongs to an ancient protein family that is linked to various human disorders. The precise role of exon 1-encoded N-terminal domains and how these influence the biological functions of human HtrA1 remain elusi