Zobrazeno 1 - 10
of 121
pro vyhledávání: '"Arnout Voet"'
Autor:
Flore Sneyers, Martijn Kerkhofs, Femke Speelman-Rooms, Kirsten Welkenhuyzen, Rita La Rovere, Ahmed Shemy, Arnout Voet, Guy Eelen, Mieke Dewerchin, Stephen W. G. Tait, Bart Ghesquière, Martin D. Bootman, Geert Bultynck
Publikováno v:
Cell Death and Disease, Vol 14, Iss 9, Pp 1-17 (2023)
Abstract Intracellular Ca2+ signals control several physiological and pathophysiological processes. The main tool to chelate intracellular Ca2+ is intracellular BAPTA (BAPTAi), usually introduced into cells as a membrane-permeant acetoxymethyl ester
Externí odkaz:
https://doaj.org/article/165f5a0201694ead8a06898f90b65886
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-19 (2023)
Abstract Although methodological advances have been made over the past years, a widely applicable, easily scalable and cost-effective procedure that can be routinely used to isolate specific ribonucleoprotein complexes (RNPs) remains elusive. We desc
Externí odkaz:
https://doaj.org/article/08aeca6d93284fbd804d4defc5d955e1
Autor:
Elien Smeets, Shengyun Huang, Xiao Yin Lee, Erika Van Nieuwenhove, Christine Helsen, Florian Handle, Lisa Moris, Sarah El Kharraz, Roy Eerlings, Wout Devlies, Mathijs Willemsen, Leoni Bücken, Teresa Prezzemolo, Stephanie Humblet‐Baron, Arnout Voet, Anne Rochtus, Ann Van Schepdael, Francis deZegher, Frank Claessens
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 13, Iss 4, Pp 2242-2253 (2022)
Abstract Background Cytochrome P450 4F3 (CYP4F3) is an ω‐hydroxylase that oxidizes leukotriene B4 (LTB4), prostaglandins, and fatty acid epoxides. LTB4 is synthesized by leukocytes and acts as a chemoattractant for neutrophils, making it an essent
Externí odkaz:
https://doaj.org/article/7d73d180cc02422d9887d30e1f9063be
Autor:
John Vaughan-Hirsch, Dongdong Li, Albert Roig Martinez, Stijn Roden, Jolien Pattyn, Shu Taira, Hitomi Shikano, Yoko Miyama, Yukari Okano, Arnout Voet, Bram Van de Poel
Publikováno v:
Frontiers in Plant Science, Vol 13 (2022)
Plants produce the volatile hormone ethylene to regulate many developmental processes and to deal with (a)biotic stressors. In seed plants, ethylene is synthesized from 1-aminocyclopropane-1-carboxylic acid (ACC) by the dedicated enzyme ACC oxidase (
Externí odkaz:
https://doaj.org/article/860ee6dfc6374333b8747fb43f2bc340
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-10 (2019)
Using Fragaceatoxin C nanopores to study peptides below 1.6 kDa is challenging. Here the authors demonstrate that nanopores can be engineered to different sizes to detect a range of peptide lengths below the previous resolution limit, and show that t
Externí odkaz:
https://doaj.org/article/09dd1600d7044d409d1462d825c5945f
Autor:
Jasper Edgar Neggers, Bert Kwanten, Tim Dierckx, Hiroki Noguchi, Arnout Voet, Lotte Bral, Kristien Minner, Bob Massant, Nicolas Kint, Michel Delforge, Thomas Vercruysse, Erkan Baloglu, William Senapedis, Maarten Jacquemyn, Dirk Daelemans
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
Cancer therapy drugs are designed to target genetic vulnerabilities, but loss-of-function screens often fail to identify essential genes in drug mechanism studies. Here the authors demonstrate CRISPRres, which exploits in-frame variation generated by
Externí odkaz:
https://doaj.org/article/9dbf9e90c64d440ea8f766544059bc01
Publikováno v:
F1000Research, Vol 6 (2018)
Protein modeling and design activities often require querying the Protein Data Bank (PDB) with a structural fragment, possibly containing gaps. For some applications, it is preferable to work on a specific subset of the PDB or with unpublished struct
Externí odkaz:
https://doaj.org/article/06df4d9f09d74144929801b9142337ca
Publikováno v:
F1000Research, Vol 6 (2017)
Protein modeling and design activities often require querying the Protein Data Bank (PDB) with a structural fragment, possibly containing gaps. For some applications, it is preferable to work on a specific subset of the PDB or with unpublished struct
Externí odkaz:
https://doaj.org/article/bf60b44502ed43db97d294bb5c4e907c
Autor:
Thomas Vercruysse, Eline Boons, Tom Venken, Els Vanstreels, Arnout Voet, Jan Steyaert, Marc De Maeyer, Dirk Daelemans
Publikováno v:
PLoS ONE, Vol 8, Iss 4, p e60259 (2013)
HIV-1 Rev is the key protein in the nucleocytoplasmic export and expression of the late viral mRNAs. An important aspect for its function is its ability to multimerize on these mRNAs. We have recently identified a llama single-domain antibody (Nb190)
Externí odkaz:
https://doaj.org/article/b2b4e6d3c7e4443d8bfa331dbd21c385
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e75762 (2013)
One of the underlying principles in drug discovery is that a biologically active compound is complimentary in shape and molecular recognition features to its receptor. This principle infers that molecules binding to the same receptor may share some c
Externí odkaz:
https://doaj.org/article/ec45505f8aa64ca6afd98e438ef509d8