Zobrazeno 1 - 9 of 9 pro vyhledávání: '"Arnout R. D. Voet"'
1
Akademický článek
Structure and stability of the designer protein WRAP-T and its permutants
Autor: Bram Mylemans, Xiao Yin Lee, Ina Laier, Christine Helsen, Arnout R. D. Voet
Publikováno v: Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract $$\beta $$ β -Propeller proteins are common natural disc-like pseudo-symmetric proteins that contain multiple repeats (‘blades’) each consisting of a 4-stranded anti-parallel $$\beta $$ β -sheet. So far, 4- to 12-bladed $$\beta $$ β -
Externí odkaz: https://doaj.org/article/4f79e968ad0342daa7075fc81ab3f3d7
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2
Akademický článek
Computational design of symmetrical eight-bladed β-propeller proteins
Autor: Hiroki Noguchi, Christine Addy, David Simoncini, Staf Wouters, Bram Mylemans, Luc Van Meervelt, Thomas Schiex, Kam Y. J. Zhang, Jeremy R. H. Tame, Arnout R. D. Voet
Publikováno v: IUCrJ, Vol 6, Iss 1, Pp 46-55 (2019)
β-Propeller proteins form one of the largest families of protein structures, with a pseudo-symmetrical fold made up of subdomains called blades. They are not only abundant but are also involved in a wide variety of cellular processes, often by actin
Externí odkaz: https://doaj.org/article/0cc44b94496f4d45a457d731be7329c6
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3
Akademický článek
Computational design of a symmetrical β-trefoil lectin with cancer cell binding activity
Autor: Daiki Terada, Arnout R. D. Voet, Hiroki Noguchi, Kenichi Kamata, Mio Ohki, Christine Addy, Yuki Fujii, Daiki Yamamoto, Yasuhiro Ozeki, Jeremy R. H. Tame, Kam Y. J. Zhang
Publikováno v: Scientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)
Abstract Computational protein design has advanced very rapidly over the last decade, but there remain few examples of artificial proteins with direct medical applications. This study describes a new artificial β-trefoil lectin that recognises Burki
Externí odkaz: https://doaj.org/article/a440be7c963c4aa4b4ba9fc614b1d221
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8
Computational design of symmetrical eight-bladed beta-propeller proteins
Autor: Hiroki Noguchi, Christine Addy, David Simoncini, Staf Wouters, Bram Mylemans, Luc Van Meervelt, Thomas Schiex, Kam Y. J. Zhang, Jeremy R. H. Tame, Arnout R. D. Voet
Publikováno v: IUCRJ
IUCrJ = International Union of Crystallography journal
IUCrJ = International Union of Crystallography journal, International Union of Crystallography 2019, 6 (1), pp.46-55. ⟨10.1107/S205225251801480X⟩
International Union of Crystallography journal
International Union of Crystallography journal, 2019, 6 (1), pp.46-55. ⟨10.1107/S205225251801480X⟩
IUCrJ 1 (6), 46-55. (2019)
International Union of Crystallography journal, International Union of Crystallography 2019, 6 (1), pp.46-55. ⟨10.1107/S205225251801480X⟩
IUCrJ
IUCrJ, Vol 6, Iss 1, Pp 46-55 (2019)
Two artificial β-propeller proteins with eight identical blades were designed, purified and crystallized. X-ray crystallography confirmed the perfectly symmetrical structures of these highly stable proteins.
β-Propeller proteins form one of th
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b0954fdc23752d7e45b346ffae584fe
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9
Evolution-Inspired Computational Design of Symmetric Proteins
Autor: Arnout R D, Voet, David, Simoncini, Jeremy R H, Tame, Kam Y J, Zhang
Publikováno v: Methods in molecular biology (Clifton, N.J.). 1529
Monomeric proteins with a number of identical repeats creating symmetrical structures are potentially very valuable building blocks with a variety of bionanotechnological applications. As such proteins do not occur naturally, the emerging field of co
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::aad50ef95ab617090a56e1baf28a8064
https://pubmed.ncbi.nlm.nih.gov/27914059
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