Identifying the science and technology dimensions of emerging public policy issues through horizon scanning.

Autor: Miles Parker, Andrew Acland, Harry J Armstrong, Jim R Bellingham, Jessica Bland, Helen C Bodmer, Simon Burall, Sarah Castell, Jason Chilvers, David D Cleevely, David Cope, Lucia Costanzo, James A Dolan, Robert Doubleday, Wai Yi Feng, H Charles J Godfray, David A Good, Jonathan Grant, Nick Green, Arnoud J Groen, Tim T Guilliams, Sunjai Gupta, Amanda C Hall, Adam Heathfield, Ulrike Hotopp, Gary Kass, Tim Leeder, Fiona A Lickorish, Leila M Lueshi, Chris Magee, Tiago Mata, Tony McBride, Natasha McCarthy, Alan Mercer, Ross Neilson, Jackie Ouchikh, Edward J Oughton, David Oxenham, Helen Pallett, James Palmer, Jeff Patmore, Judith Petts, Jan Pinkerton, Richard Ploszek, Alan Pratt, Sophie A Rocks, Neil Stansfield, Elizabeth Surkovic, Christopher P Tyler, Andrew R Watkinson, Jonny Wentworth, Rebecca Willis, Patrick K A Wollner, Kim Worts, William J Sutherland

Publikováno v: PLoS ONE, Vol 9, Iss 5, p e96480 (2014)

Public policy requires public support, which in turn implies a need to enable the public not just to understand policy but also to be engaged in its development. Where complex science and technology issues are involved in policy making, this takes ti

Externí odkaz: https://doaj.org/article/20ff35e63a454adda257729fe483c243

Proteomics-Based Detection of Immune Dysfunction in an Elite Adventure Athlete Trekking Across the Antarctica

Autor: David C. Nieman, Arnoud J. Groen, Artyom Pugachev, Andrew J. Simonson, Kristine Polley, Karma James, Bassem F. El-Khodor, Saradhadevi Varadharaj, Claudia Hernández-Armenta

Publikováno v: Proteomes, Vol 8, Iss 1, p 4 (2020)

Proteomics monitoring of an elite adventure athlete (age 33 years) was conducted over a 28-week period that culminated in the successful, solo, unassisted, and unsupported two month trek across the Antarctica (1500 km). Training distress was monitore

Externí odkaz: https://doaj.org/article/525a0ad3f2004210a3bc2f2543de5579

TET2 is a component of the estrogen receptor complex and controls 5mC to 5hmC conversion at estrogen receptor cis-regulatory regions

Autor: Carmen Gonzalez Tejedo, Kamal Kishore, Areeb Mahtey, Shi-Qing Mao, Clive D'Santos, Stacey Jamieson, Arnoud J. Groen, Rebecca Broome, Shankar Balasubramanian, Rasmus Siersbæk, Igor Chernukhin, Evangelia K. Papachristou, Vasiliki Theodorou, Anca M. Farcas, Jason S. Carroll

Publikováno v: Cell Reports, Vol 34, Iss 8, Pp 108776-(2021)
Broome, R, Chernukhin, I, Jamieson, S, Kishore, K, Papachristou, E K, Mao, S-Q, Tejedo, C G, Mahtey, A, Theodorou, V, Groen, A J, D'Santos, C, Balasubramanian, S, Farcas, A M, Siersbaek, R & Carroll, J S 2021, ' TET2 is a component of the estrogen receptor complex and controls 5mC to 5hmC conversion at estrogen receptor cis-regulatory regions ', Cell Reports, vol. 34, no. 8, 108776 . https://doi.org/10.1016/j.celrep.2021.108776
Cell Reports

Summary Estrogen receptor-α (ER) drives tumor development in ER-positive (ER+) breast cancer. The transcription factor GATA3 has been closely linked to ER function, but its precise role in this setting remains unclear. Quantitative proteomics was us

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::855ab63375b08c0e118cc34f14f6e503
http://www.sciencedirect.com/science/article/pii/S2211124721000899

Proteomic Profiling and Monitoring of Training Distress and Illness in University Swimmers During a 25-Week Competitive Season

Autor: Artyom Pugachev, Amy M. Knab, David C. Nieman, Arnoud J. Groen, Laura M. Zingaretti

Publikováno v: Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
Frontiers in Physiology, Vol 11 (2020)
Frontiers in Physiology
Digital.CSIC. Repositorio Institucional del CSIC
instname

[Purpose]: To evaluate relationships of proteomics data, athlete-reported illness, athlete training distress (TDS), and coaches’ ratings of distress and performance over the course of the competitive season.
[Methods]: Thirty-five NCAA Divisio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac67e0f03d7ecab2a56e9febc26d070c
https://ddd.uab.cat/record/255919

Blood Proteomics-Based Detection of Upregulated Lipid Metabolism and Immune Dysfunction in an Elite Adventure Athlete Trekking Across Antarctica

Autor: Kristine Polley, Arnoud J. Groen, Artyom Pugachev, Andrew Simonson, Bassem F. El-Khodor, Karma James, David C. Nieman, Saradhadevi Varadharaj, Claudia Hernandez-Armenta

Publikováno v: Curr Dev Nutr

OBJECTIVES: Proteomics when combined with psychological, nutrition, and performance measures may serve as a useful monitoring system for immune dysfunction, training distress, and exercise-induced muscle damage and exhaustion in athletes. Global prot

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::111b6e79a84c552f9ef7168113a9c3a1
https://doi.org/10.1093/cdn/nzaa066_015