Glu311 and Arg337 Stabilize a Closed Active-site Conformation and Provide a Critical Catalytic Base and Countercation for Green Bioluminescence in Beetle Luciferases.

Autor: Viviani VR; Graduate Program of Biotechnology and Environmental Monitoring, Federal University of São Carlos (UFSCar) , Rodovia João Leme dos Santos, km 110, Itinga, Sorocaba, SP, Brazil., Simões A; Graduate Program of Biotechnology and Environmental Monitoring, Federal University of São Carlos (UFSCar) , Rodovia João Leme dos Santos, km 110, Itinga, Sorocaba, SP, Brazil.; Graduate Program of Evolutive Genetics and Molecular Biology, Federal University of São Carlos (UFSCar) , São Carlos, SP, Brazil., Bevilaqua VR; Graduate Program of Evolutive Genetics and Molecular Biology, Federal University of São Carlos (UFSCar) , São Carlos, SP, Brazil., Gabriel GV; Graduate Program of Evolutive Genetics and Molecular Biology, Federal University of São Carlos (UFSCar) , São Carlos, SP, Brazil., Arnoldi FG; Ribeirão Preto School of Medicine, São Paulo University , Ribeirão Preto, São Paulo, Brazil., Hirano T; Department of Engineering Science, Graduate School of Informatics and Engineering, The University of Electro-Communications , Chofu, Tokyo 182-8585, Japan.

Publikováno v: Biochemistry [Biochemistry] 2016 Aug 30; Vol. 55 (34), pp. 4764-76. Date of Electronic Publication: 2016 Aug 18.

Synergy of chemotherapy and immunotherapy revealed by a genome-scale analysis of murine tuberculosis.

Autor: Rodrigues RF; The Centre for Tuberculosis Research, Department of Biochemistry and Immunology, Ribeirão Preto School of Medicine, University of São Paulo, São Paulo, Ribeirao Preto, 14049-900, Brazil., Zárate-Bladés CR; The Centre for Tuberculosis Research, Department of Biochemistry and Immunology, Ribeirão Preto School of Medicine, University of São Paulo, São Paulo, Ribeirao Preto, 14049-900, Brazil zarate.blades@gmail.com., Rios WM; The Centre for Tuberculosis Research, Department of Biochemistry and Immunology, Ribeirão Preto School of Medicine, University of São Paulo, São Paulo, Ribeirao Preto, 14049-900, Brazil., Soares LS; The Centre for Tuberculosis Research, Department of Biochemistry and Immunology, Ribeirão Preto School of Medicine, University of São Paulo, São Paulo, Ribeirao Preto, 14049-900, Brazil., Souza PR; The Centre for Tuberculosis Research, Department of Biochemistry and Immunology, Ribeirão Preto School of Medicine, University of São Paulo, São Paulo, Ribeirao Preto, 14049-900, Brazil., Brandão IT; The Centre for Tuberculosis Research, Department of Biochemistry and Immunology, Ribeirão Preto School of Medicine, University of São Paulo, São Paulo, Ribeirao Preto, 14049-900, Brazil., Masson AP; The Centre for Tuberculosis Research, Department of Biochemistry and Immunology, Ribeirão Preto School of Medicine, University of São Paulo, São Paulo, Ribeirao Preto, 14049-900, Brazil., Arnoldi FG; The Centre for Tuberculosis Research, Department of Biochemistry and Immunology, Ribeirão Preto School of Medicine, University of São Paulo, São Paulo, Ribeirao Preto, 14049-900, Brazil., Ramos SG; Department of Pathology, Ribeirão Preto School of Medicine, University of São Paulo, Ribeirao Preto, São Paulo, 14049-900, Brazil., Letourneur F; Université Paris-Descartes, Institut Cochin and INSERM U1016, CNRS (CMRS 8104), Paris, 75014, France., Jacques S; Université Paris-Descartes, Institut Cochin and INSERM U1016, CNRS (CMRS 8104), Paris, 75014, France., Cagnard N; Université Paris-Descartes, Institut Cochin and INSERM U1016, CNRS (CMRS 8104), Paris, 75014, France Hôpital Necker, Paris, 75015, France., Chiocchia G; Université Paris-Descartes, Institut Cochin and INSERM U1016, CNRS (CMRS 8104), Paris, 75014, France., Silva CL; The Centre for Tuberculosis Research, Department of Biochemistry and Immunology, Ribeirão Preto School of Medicine, University of São Paulo, São Paulo, Ribeirao Preto, 14049-900, Brazil.

Publikováno v: The Journal of antimicrobial chemotherapy [J Antimicrob Chemother] 2015; Vol. 70 (6), pp. 1774-83. Date of Electronic Publication: 2015 Feb 16.

The luciferin binding site residues C/T311 (S314) influence the bioluminescence color of beetle luciferases through main-chain interaction with oxyluciferin phenolate.

Autor: Viviani VR; Department of Physics, Chemistry and Mathematics, Graduate Program of Biotechnology and Environmental Monitoring, Federal University of São Carlos (UFSCAR), Rodovia João Leme dos Santos, km 110, Itinga, Sorocaba, SP, Brazil. viviani@ufscar.br, Amaral DT, Neves DR, Simões A, Arnoldi FG

Publikováno v: Biochemistry [Biochemistry] 2013 Jan 08; Vol. 52 (1), pp. 19-27. Date of Electronic Publication: 2012 Dec 13.

Haplotypes of the bovine IgG2 heavy gamma chain in tick-resistant and tick-susceptible breeds of cattle.

Autor: Carvalho WA; Department of Biochemistry and Immunology, Ribeirão Preto School of Medicine, University of São Paulo, Av. Bandeirantes 3900, Ribeirão Preto, SP, Brazil., Ianella P, Arnoldi FG, Caetano AR, Maruyama SR, Ferreira BR, Conti LH, da Silva MR, Paula JO, Maia AA, Santos IK

Publikováno v: Immunogenetics [Immunogenetics] 2011 May; Vol. 63 (5), pp. 319-24. Date of Electronic Publication: 2011 Feb 08.

Pyrearinus termitilluminans larval click beetle luciferase: active site properties, structure and function relationships and comparison with other beetle luciferases.

Autor: Silva Neto AJ; Departamento de Biologia, Instituto de Biociências, Universidade Estadual Paulista, Brazil., Scorsato V, Arnoldi FG, Viviani VR

Publikováno v: Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology [Photochem Photobiol Sci] 2009 Dec; Vol. 8 (12), pp. 1748-54. Date of Electronic Publication: 2009 Oct 23.