Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Arnold Tan"'
Autor:
Arnold Tan, Awais Z. Younis, Alexander Evans, Jade V. Creighton, Clare Coveny, David J. Boocock, Craig Sale, Gareth G. Lavery, Amanda S. Coutts, Craig L. Doig
Publikováno v:
Cell Death Discovery, Vol 9, Iss 1, Pp 1-13 (2023)
Abstract The ADP-ribosyltransferase, PARP1 enzymatically generates and applies the post-translational modification, ADP-Ribose (ADPR). PARP1 roles in genome maintenance are well described, but recent work highlights roles in many fundamental processe
Externí odkaz:
https://doaj.org/article/53b6b599c8154c79ab5165547b13a0c9
Autor:
Arnold Tan, Craig L. Doig
Publikováno v:
Frontiers in Molecular Biosciences, Vol 8 (2021)
Declines in cellular nicotinamide adenine dinucleotide (NAD) contribute to metabolic dysfunction, increase susceptibility to disease, and occur as a result of pathogenic infection. The enzymatic cleavage of NAD+ transfers ADP-ribose (ADPr) to substra
Externí odkaz:
https://doaj.org/article/28ea37ebc97546c5b30cd65d0e0a4175
Autor:
Junhan, Arnold Tan
We start by building up some theory to state Wagner's Theorem, and then prove it using Kuratowski's Theorem, a proof of which is found in Diester (2000). Following this, we establish some connections between the chromatic number of a graph and some o
Externí odkaz:
http://arxiv.org/abs/1901.08171
Autor:
Junhan, Arnold Tan
A two-part report, containing (unrelated) essays on subobject classifiers and on monads.
Externí odkaz:
http://arxiv.org/abs/1901.08165
Autor:
Junhan, Arnold Tan
The goal of this report is to investigate the variety of Hausdorff compactifications of $\mathbb{R}$. The Alexandroff one-point compactification, the two-point compactification, and the Stone-Cech compactification are all clearly different. The ultim
Externí odkaz:
http://arxiv.org/abs/1901.08167
Autor:
Junhan, Arnold Tan
Given a small abelian category $\mathcal{A}$, the Freyd-Mitchell embedding theorem states the existence of a ring $R$ and an exact full embedding $\mathcal{A} \rightarrow R$-Mod. This theorem is useful as it allows one to prove general results about
Externí odkaz:
http://arxiv.org/abs/1901.08591
Autor:
Arnold Tan, Awais Younis, Jade Creighton, Alexander Evans, Clare Coveney, David Boocock, Craig Sale, Gareth Lavery, Amanda Coutts, Craig Doig
Poly-(ADP-ribose)polymerase 1 (PARP1) enzymatically generates and applies the post-translational modification, as mono (MAR) or poly (PAR) ADP-Ribose (ADPR) chains. PARP1 roles in genome maintenance are well described, but recent work highlight roles
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::613df06c3c60ee035bc4f205b9680257
https://doi.org/10.21203/rs.3.rs-2227540/v1
https://doi.org/10.21203/rs.3.rs-2227540/v1
Autor:
Alexander C.O. Evans, David J. Boocock, Craig Sale, Arnold Tan, Craig Doig, Nick Weir, Jade Creighton
Publikováno v:
Endocrine Abstracts.
Publikováno v:
Endocrine Abstracts.
Autor:
David Boocock, Clare Coveney, Jade Creighton, Craig Doig, Craig Sale, Nick Weir, Awais Younis, Arnold Tan
Publikováno v:
Journal of the Endocrine Society. 6:A724-A724
Background NAD+-dependent PARP1 (Poly-(ADP-ribosyl)polymerase 1) generates the post-translational modification ADP-Ribosylation (ADPR). Given PARP1-ADPR determines cellular NAD+ availability, which in turn impacts a range of hormonally governed actio