Zobrazeno 1 - 10
of 73
pro vyhledávání: '"Arnold Reynaldi"'
Autor:
Deborah Cromer, Arnold Reynaldi, Ainslie Mitchell, Timothy E. Schlub, Jennifer A. Juno, Adam K. Wheatley, Stephen J. Kent, David S. Khoury, Miles P. Davenport
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-9 (2024)
Abstract The ongoing evolution of the SARS-CoV-2 virus has led to a move to update vaccine antigens in 2022 and 2023. These updated antigens were chosen and approved based largely on in vitro neutralisation titres against recent SARS-CoV-2 variants.
Externí odkaz:
https://doaj.org/article/2e91dd6127a5475a935ffe022d664285
Autor:
Deborah Cromer, Megan Steain, Arnold Reynaldi, Timothy E. Schlub, Shanchita R. Khan, Sarah C. Sasson, Stephen J. Kent, David S. Khoury, Miles P. Davenport
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-9 (2023)
In this study, the authors perform a meta-analysis of COVID-19 vaccine effectiveness studies and compare observed protection against severe disease with model-based estimates of neutralising antibody titres. Their results show that SARS-CoV-2 antibod
Externí odkaz:
https://doaj.org/article/0ffd847cd5604f1bbad7250751912307
Autor:
Kevin J. Selva, Pradhipa Ramanathan, Ebene R. Haycroft, Arnold Reynaldi, Deborah Cromer, Chee Wah Tan, Lin-Fa Wang, Bruce D. Wines, P. Mark Hogarth, Laura E. Downie, Samantha K. Davis, Ruth A. Purcell, Helen E. Kent, Jennifer A. Juno, Adam K. Wheatley, Miles P. Davenport, Stephen J. Kent, Amy W. Chung
Publikováno v:
JCI Insight, Vol 8, Iss 18 (2023)
Understanding mucosal antibody responses from SARS-CoV-2 infection and/or vaccination is crucial to develop strategies for longer term immunity, especially against emerging viral variants. We profiled serial paired mucosal and plasma antibodies from
Externí odkaz:
https://doaj.org/article/5642c4f059134a179ab08b3553b928dd
Autor:
Jennifer R. Habel, Brendon Y. Chua, Lukasz Kedzierski, Kevin J. Selva, Timon Damelang, Ebene R. Haycroft, Thi H.O. Nguyen, Hui-Fern Koay, Suellen Nicholson, Hayley A. McQuilten, Xiaoxiao Jia, Lilith F. Allen, Luca Hensen, Wuji Zhang, Carolien E. van de Sandt, Jessica A. Neil, Katherine Pragastis, Jillian S.Y. Lau, Jaycee Jumarang, E. Kaitlynn Allen, Fatima Amanant, Florian Krammer, Kathleen M. Wragg, Jennifer A. Juno, Adam K. Wheatley, Hyon-Xhi Tan, Gabrielle Pell, Susan Walker, Jennifer Audsley, Arnold Reynaldi, Irani Thevarajan, Justin T. Denholm, Kanta Subbarao, Miles P. Davenport, P. Mark Hogarth, Dale I. Godfrey, Allen C. Cheng, Steven Y.C. Tong, Katherine Bond, Deborah A. Williamson, James H. McMahon, Paul G. Thomas, Pia S. Pannaraj, Fiona James, Natasha E. Holmes, Olivia C. Smibert, Jason A. Trubiano, Claire L. Gordon, Amy W. Chung, Clare L. Whitehead, Stephen J. Kent, Martha Lappas, Louise C. Rowntree, Katherine Kedzierska
Publikováno v:
JCI Insight, Vol 8, Iss 7 (2023)
Pregnancy poses a greater risk for severe COVID-19; however, underlying immunological changes associated with SARS-CoV-2 during pregnancy are poorly understood. We defined immune responses to SARS-CoV-2 in unvaccinated pregnant and nonpregnant women
Externí odkaz:
https://doaj.org/article/5baf2d86cad54efcaef6a7913823280a
Autor:
Adam K. Wheatley, Jennifer A. Juno, Jing J. Wang, Kevin J. Selva, Arnold Reynaldi, Hyon-Xhi Tan, Wen Shi Lee, Kathleen M. Wragg, Hannah G. Kelly, Robyn Esterbauer, Samantha K. Davis, Helen E. Kent, Francesca L. Mordant, Timothy E. Schlub, David L. Gordon, David S. Khoury, Kanta Subbarao, Deborah Cromer, Tom P. Gordon, Amy W. Chung, Miles P. Davenport, Stephen J. Kent
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
Longitudinal analyses are needed to show how the immune response to Sars-Cov-2 infection changes over time. Here, the authors use multiple strategies to profile the change in immune cell responses from patients with convalescent COVID-19 over the cou
Externí odkaz:
https://doaj.org/article/e4e8f1c116754d5288a334fd4274b5ac
Autor:
Deborah Cromer, PhD, Megan Steain, PhD, Arnold Reynaldi, PhD, Timothy E Schlub, PhD, Adam K Wheatley, PhD, Jennifer A Juno, PhD, Stephen J Kent, MD, James A Triccas, PhD, David S Khoury, PhD, Miles P Davenport, DPhil
Publikováno v:
The Lancet Microbe, Vol 3, Iss 1, Pp e52-e61 (2022)
Summary: Background: Several SARS-CoV-2 variants of concern have been identified that partly escape serum neutralisation elicited by current vaccines. Studies have also shown that vaccines demonstrate reduced protection against symptomatic infection
Externí odkaz:
https://doaj.org/article/23977c96b0e84581a0a9625eb4ecfd5a
Autor:
Wen Shi Lee, Arnold Reynaldi, Thakshila Amarasena, Miles P. Davenport, Matthew S. Parsons, Stephen J. Kent
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Broadly neutralising antibodies (bNAbs) may play an important role in future strategies for HIV control. The development of anti-drug antibody (ADA) responses can reduce the efficacy of passively transferred bNAbs but the impact of ADA is imperfectly
Externí odkaz:
https://doaj.org/article/099d8252a5c742e2aa9272fa91e71d68
Autor:
Wen Shi Lee, Kevin John Selva, Samantha K. Davis, Bruce D. Wines, Arnold Reynaldi, Robyn Esterbauer, Hannah G. Kelly, Ebene R. Haycroft, Hyon-Xhi Tan, Jennifer A. Juno, Adam K. Wheatley, P. Mark Hogarth, Deborah Cromer, Miles P. Davenport, Amy W. Chung, Stephen J. Kent
Publikováno v:
Cell Reports Medicine, Vol 2, Iss 6, Pp 100296- (2021)
Summary: The capacity of antibodies to engage with immune cells via the Fc region is important in preventing and controlling many infectious diseases. The evolution of such antibodies during convalescence from coronavirus disease 2019 (COVID-19) is l
Externí odkaz:
https://doaj.org/article/055cad52624241e08920af0c14bd5a0d
Autor:
Arnold Reynaldi, Arlene E. Dent, Timothy E. Schlub, Sidney Ogolla, Rosemary Rochford, Miles P. Davenport
Publikováno v:
Malaria Journal, Vol 18, Iss 1, Pp 1-9 (2019)
Abstract Background Studies of the association between the level of anti-malarial antibody and protection from malaria infection can yield conflicting results if they fail to take into account differences in the malaria transmission rate. This can oc
Externí odkaz:
https://doaj.org/article/139e27fbf6cf4d70981db0531bc0fa76
Autor:
Kevin J Selva, Samantha K Davis, Ebene R Haycroft, Wen Shi Lee, Ester Lopez, Arnold Reynaldi, Miles P Davenport, Helen E Kent, Jennifer A Juno, Amy W Chung, Stephen J Kent
Publikováno v:
Clinical & Translational Immunology, Vol 10, Iss 11, Pp n/a-n/a (2021)
Abstract Objectives SARS‐CoV‐2 can be transmitted by aerosols, and the ocular surface may be an important route of transmission. Little is known about protective antibody responses to SARS‐CoV‐2 in tears after infection or vaccination. We ana
Externí odkaz:
https://doaj.org/article/0dcabd136d5f4092a7816b36c8cabccb