Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Arnold Leckstrom"'
Publikováno v:
Life sciences. 170
Aims To investigate the role of glucose and insulin in the regulation of hepatic fat mass and obesity associated ( Fto ) gene expression and the role of hepatic Fto in the regulation of gluconeogenic gene expression. Main methods To determine the eff
Publikováno v:
Life Sciences. 88:664-669
Aims The central melanocortin system regulates a variety of metabolic functions including lipid metabolism and hepatic lipogenic gene expression. The objective of the present study was to determine whether central melanocortin regulates hepatic lipog
Autor:
Pei San LewP.S. Lew, Takafumi YamaguchiT. Yamaguchi, Tooru M. Mizuno, Davie Wong, Jacquie Schwartz, Janice G. Dodd, Arnold Leckstrom
Publikováno v:
Canadian Journal of Physiology and Pharmacology. 87:839-849
Space travelers experience anorexia and body weight loss in a microgravity environment, and microgravity-like situations cause changes in hypothalamic activity. Hypothalamic melanocortins play a critical role in the regulation of metabolism. Therefor
Publikováno v:
Endocrinology. 146:1523-1531
IGF-independent effects of IGF-binding protein-3 (IGFBP-3) have been demonstrated in vitro; however, the physiological significance of these effects in vivo is unclear. We generated two transgenic (Tg) mouse strains that overexpress a human Gly56/Gly
Publikováno v:
Neuropeptides. 45(2)
Impairments in leptin-melanocortin signaling are associated with insulin-deficient diabetes and leptin treatment has been shown to be effective in reversing hyperglycemia in animal models of type 1 diabetes. Therefore, we hypothesized that enhanced c
Autor:
Pei San, Lew, Davie, Wong, Takafumi, Yamaguchi, Arnold, Leckstrom, Jacquie, Schwartz, Janice G, Dodd, Tooru M, Mizuno
Publikováno v:
Canadian journal of physiology and pharmacology. 87(10)
Space travelers experience anorexia and body weight loss in a microgravity environment, and microgravity-like situations cause changes in hypothalamic activity. Hypothalamic melanocortins play a critical role in the regulation of metabolism. Therefor
Publikováno v:
Behavioural brain research. 194(1)
Neurotensin plays a role in regulating feeding behavior. Central injection of neurotensin reduces food intake and the anorectic effect of neurotensin is mediated through neurotensin receptor 1 (Ntsr1). Ntsr1-deficient mice are characterized by mild h
Publikováno v:
Diabetes
Ожирение и метаболизм, Vol 6, Iss 4, Pp 50-51 (2009)
Ожирение и метаболизм, Vol 6, Iss 4, Pp 50-51 (2009)
OBJECTIVE—Xenin, a 25–amino acid peptide, was initially isolated from human gastric mucosa. Plasma levels of xenin rise after a meal in humans, and administration of xenin inhibits feeding in rats and chicks. However, little is known about the me
Publikováno v:
Canadian Journal of Physiology & Pharmacology. Dec2009, Vol. 87 Issue 12, pC-1-C-7. 7p.
Publikováno v:
Diabetes; Jan2009, Vol. 58 Issue 1, p87-94, 8p, 8 Graphs