Zobrazeno 1 - 10
of 465
pro vyhledávání: '"Arnold J M, Driessen"'
Autor:
Adéla Melcrová, Sourav Maity, Josef Melcr, Niels A. W. de Kok, Mariella Gabler, Jonne van der Eyden, Wenche Stensen, John S. M. Svendsen, Arnold J. M. Driessen, Siewert J. Marrink, Wouter H. Roos
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
Abstract Antimicrobial resistance is one of the leading concerns in medical care. Here we study the mechanism of action of an antimicrobial cationic tripeptide, AMC-109, by combining high speed-atomic force microscopy, molecular dynamics, fluorescenc
Externí odkaz:
https://doaj.org/article/dc03a19cfff44e7683a6bac15ecc3668
Publikováno v:
Biotechnology for Biofuels and Bioproducts, Vol 16, Iss 1, Pp 1-10 (2023)
Abstract Rapid and effective consumption of d-xylose by Saccharomyces cerevisiae is essential for cost-efficient cellulosic bioethanol production. Hence, heterologous d-xylose metabolic pathways have been introduced into S. cerevisiae. An effective s
Externí odkaz:
https://doaj.org/article/62652926ce584f378e80877316a6481c
Publikováno v:
Biotechnology for Biofuels and Bioproducts, Vol 15, Iss 1, Pp 1-13 (2022)
Abstract Acetic acid is a growth inhibitor generated during alcoholic fermentation and pretreatment of lignocellulosic biomass, a major feedstock to produce bioethanol. An understanding of the acetic acid tolerance mechanisms is pivotal for the indus
Externí odkaz:
https://doaj.org/article/505867ba3bf1427c90b215254725ca02
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 10 (2022)
Filamentous fungi are highly productive cell factories, many of which are industrial producers of enzymes, organic acids, and secondary metabolites. The increasing number of sequenced fungal genomes revealed a vast and unexplored biosynthetic potenti
Externí odkaz:
https://doaj.org/article/497be4fc9edb47a28bf9a0a2a3eb8d22
Autor:
László Mózsik, Mirthe Hoekzema, Niels A. W. de Kok, Roel A. L. Bovenberg, Yvonne Nygård, Arnold J. M. Driessen
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract Filamentous fungi are historically known to be a rich reservoir of bioactive compounds that are applied in a myriad of fields ranging from crop protection to medicine. The surge of genomic data available shows that fungi remain an excellent
Externí odkaz:
https://doaj.org/article/4561eafae88d41fcb7ce654ae2c2f5db
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-16 (2021)
Abstract In bacteria, the SecA ATPase provides the driving force for protein secretion via the SecYEG translocon. While the dynamic interplay between SecA and SecYEG in translocation is widely appreciated, it is not clear how SecA associates with the
Externí odkaz:
https://doaj.org/article/1c394121d58f465a8a690efb6cc8ef7e
Publikováno v:
Microbial Cell Factories, Vol 18, Iss 1, Pp 1-13 (2019)
Abstract Background Orthogonal, synthetic control devices were developed for Penicillium chrysogenum, a model filamentous fungus and industrially relevant cell factory. In the synthetic transcription factor, the QF DNA-binding domain of the transcrip
Externí odkaz:
https://doaj.org/article/015bf8e98a61485c8e613c29474ba48f
Publikováno v:
ACS Omega, Vol 4, Iss 3, Pp 5293-5303 (2019)
Externí odkaz:
https://doaj.org/article/97c5032db720421789619d46eb462a68
Autor:
Sietske Grijseels, Carsten Pohl, Jens Christian Nielsen, Zahida Wasil, Yvonne Nygård, Jens Nielsen, Jens C. Frisvad, Kristian Fog Nielsen, Mhairi Workman, Thomas Ostenfeld Larsen, Arnold J. M. Driessen, Rasmus John Normand Frandsen
Publikováno v:
Fungal Biology and Biotechnology, Vol 5, Iss 1, Pp 1-17 (2018)
Abstract Background Filamentous fungi are important producers of secondary metabolites, low molecular weight molecules that often have bioactive properties. Calbistrin A is a secondary metabolite with an interesting structure that was recently found
Externí odkaz:
https://doaj.org/article/f0be01b324f04a1daa9ae9137fa160f3
Publikováno v:
PLoS ONE, Vol 15, Iss 4, p e0231290 (2020)
The L-δ-(α-aminoadipoyl)-L-cysteinyl-D-valine synthetase (ACVS) is a nonribosomal peptide synthetase (NRPS) that fulfills a crucial role in the synthesis of β-lactams. Although some of the enzymological aspects of this enzyme have been elucidated,
Externí odkaz:
https://doaj.org/article/78e9c8e963fe4b0fbc19e95923ce77bc