Zobrazeno 1 - 10
of 3 258
pro vyhledávání: '"Arnold I"'
Autor:
Maneesh Dave, Atul Dev, Rodrigo A. Somoza, Nan Zhao, Satish Viswanath, Pooja Rani Mina, Prathyush Chirra, Verena Carola Obmann, Ganapati H. Mahabeleshwar, Paola Menghini, Blythe Durbin-Johnson, Jan Nolta, Christopher Soto, Abdullah Osme, Lam T. Khuat, William J. Murphy, Arnold I. Caplan, Fabio Cominelli
Publikováno v:
npj Regenerative Medicine, Vol 9, Iss 1, Pp 1-16 (2024)
Abstract Mesenchymal stem cells (MSCs) are novel therapeutics for the treatment of Crohn’s disease. However, their mechanism of action is unclear, especially in disease-relevant chronic models of inflammation. Thus, we used SAMP-1/YitFc (SAMP), a c
Externí odkaz:
https://doaj.org/article/1f75ae80e5f44a7d8febf9ed44b27251
Autor:
Junhui Hu, Ping Tan, Moe Ishihara, Nicholas A. Bayley, Shiruyeh Schokrpur, Jeremy G. Reynoso, Yangjun Zhang, Raymond J. Lim, Camelia Dumitras, Lu Yang, Steven M. Dubinett, Parmjit S. Jat, Jacques Van Snick, Jiaoti Huang, Arnold I. Chin, Robert M. Prins, Thomas G. Graeber, Hua Xu, Lily Wu
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 8, Iss 1, Pp 1-16 (2023)
Abstract Loss of function of the von Hippel-Lindau (VHL) tumor suppressor gene is a hallmark of clear cell renal cell carcinoma (ccRCC). The importance of heterogeneity in the loss of this tumor suppressor has been under reported. To study the impact
Externí odkaz:
https://doaj.org/article/7fbb896806994806aeb3daa83568734f
Autor:
Jerry M. Spiegel, Muzimkhulu Zungu, Annalee Yassi, Karen Lockhart, Kerry Sidwell Wilson, Arnold I. Okpani, David Jones, Natasha Sanabria
Publikováno v:
Revista Panamericana de Salud Pública, Vol 47, Iss 33, Pp 1-9 (2023)
Objectives. To ascertain whether and how working as a partnership of two World Health Organization collaborating centres (WHOCCs), based respectively in the Global North and Global South, can add insights on “what works to protect healthcare worker
Externí odkaz:
https://doaj.org/article/2df3f70eafea46888c8be9a01d14364f
Autor:
Arnold I. Okpani, Karen Lockhart, Jennifer M. Grant, Stephen Barker, Jocelyn A. Srigley, Annalee Yassi
Publikováno v:
Frontiers in Public Health, Vol 11 (2023)
The COVID-19 pandemic highlighted hurdles for healthcare delivery and personnel globally. Vaccination has been an important tool for preventing severe illness and death in healthcare workers (HCWs) as well as the public at large. However, vaccination
Externí odkaz:
https://doaj.org/article/605f221820704081a1149ae85a9eba8a
Autor:
Maya Breitman, Tracey L. Bonfield, Arnold I. Caplan, Hillard M. Lazarus, Maricela Haghiac, Susan LaSalvia, Jane Reese‐Koc, Nora G. Singer
Publikováno v:
ACR Open Rheumatology, Vol 4, Iss 2, Pp 152-160 (2022)
Objective Seropositive rheumatoid arthritis (RA) is a chronic autoimmune disease that is rarely “cured.” Human mesenchymal stem cells (hMSCs) are known to reduce inflammation and restore immune homeostasis. However, methods for predicting therape
Externí odkaz:
https://doaj.org/article/a7bd0d1395f0457a964cc475331d0a16
Autor:
Tracey L. Bonfield, Morgan T. Sutton, David R. Fletcher, Michael A. Folz, Vaishnavi Ragavapuram, Rodrigo A. Somoza, Arnold I. Caplan
Publikováno v:
Stem Cells Translational Medicine, Vol 10, Iss 8, Pp 1202-1216 (2021)
Abstract Chronic nontuberculous mycobacterial infections with Mycobacterium avium and Mycobacterium intracellulare complicate bronchiectasis, chronic obstructive airway disease, and the health of aging individuals. These insidious intracellular patho
Externí odkaz:
https://doaj.org/article/972fcace7d3b45f7bcc6940fc38549bb
Autor:
Giacomo Lanzoni, Elina Linetsky, Diego Correa, Shari Messinger Cayetano, Roger A. Alvarez, Dimitrios Kouroupis, Ana Alvarez Gil, Raffaella Poggioli, Phillip Ruiz, Antonio C. Marttos, Khemraj Hirani, Crystal A. Bell, Halina Kusack, Lisa Rafkin, David Baidal, Andrew Pastewski, Kunal Gawri, Clarissa Leñero, Alejandro M. A. Mantero, Sarah W. Metalonis, Xiaojing Wang, Luis Roque, Burlett Masters, Norma S. Kenyon, Enrique Ginzburg, Xiumin Xu, Jianming Tan, Arnold I. Caplan, Marilyn K. Glassberg, Rodolfo Alejandro, Camillo Ricordi
Publikováno v:
Stem Cells Translational Medicine, Vol 10, Iss 5, Pp 660-673 (2021)
Abstract Acute respiratory distress syndrome (ARDS) in COVID‐19 is associated with high mortality. Mesenchymal stem cells are known to exert immunomodulatory and anti‐inflammatory effects and could yield beneficial effects in COVID‐19 ARDS. The
Externí odkaz:
https://doaj.org/article/9d1fa9e738bc472aab4a9772e4e11f97
Autor:
Wenchun Qu, Zhen Wang, Joshua M. Hare, Guojun Bu, Jorge M. Mallea, Jorge M. Pascual, Arnold I. Caplan, Joanne Kurtzberg, Abba C. Zubair, Eva Kubrova, Erica Engelberg‐Cook, Tarek Nayfeh, Vishal P. Shah, James C. Hill, Michael E. Wolf, Larry J. Prokop, M. Hassan Murad, Fred P. Sanfilippo
Publikováno v:
Stem Cells Translational Medicine, Vol 9, Iss 9, Pp 1007-1022 (2020)
Abstract Severe cases of COVID‐19 infection, often leading to death, have been associated with variants of acute respiratory distress syndrome (ARDS). Cell therapy with mesenchymal stromal cells (MSCs) is a potential treatment for COVID‐19 ARDS b
Externí odkaz:
https://doaj.org/article/c511fe03c1b94457b87bb68498207d64
Publikováno v:
Case Reports in Urology, Vol 2022 (2022)
Cancer is a significant cause of morbidity and mortality in recipients of renal transplantation. The vast majority develop from recipient origins, whereas donor-derived malignancies are exceedingly rare. We report 2 cases of poorly differentiated don
Externí odkaz:
https://doaj.org/article/e081ff037aa643c68a4e9acdc3c0c0cc
Autor:
Tracey L. Bonfield, Morgan T. Sutton, David R. Fletcher, Jane Reese-Koc, Erica A. Roesch, Hillard M. Lazarus, James F. Chmiel, Arnold I. Caplan
Publikováno v:
Pharmaceuticals, Vol 16, Iss 2, p 220 (2023)
Human Mesenchymal Stem Cell (hMSC) immunotherapy has been shown to provide both anti-inflammatory and anti-microbial effectiveness in a variety of diseases. The clinical potency of hMSCs is based upon an initial direct hMSC effect on the pro-inflamma
Externí odkaz:
https://doaj.org/article/2cce549d1cb548528d249719d866e57c