Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Arnold Hayer"'
Autor:
Damien Garbett, Anjali Bisaria, Changsong Yang, Dannielle G. McCarthy, Arnold Hayer, W. E. Moerner, Tatyana M. Svitkina, Tobias Meyer
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-18 (2020)
In vivo, cells migrate across a diverse landscape of extracellular matrix containing gaps which present a challenge for cells to protrude across. Here, the authors show that T-Plastin strengthens protrusive actin networks to promote protrusion, extra
Externí odkaz:
https://doaj.org/article/59bc2c586f4e4738a09ac0f4b0640fca
Publikováno v:
PLoS Pathogens, Vol 12, Iss 5, p e1005603 (2016)
Vascular endothelial cells act as gatekeepers that protect underlying tissue from blood-borne toxins and pathogens. Nevertheless, endothelial cells are able to internalize large fibrin clots and apoptotic debris from the bloodstream, although the pre
Externí odkaz:
https://doaj.org/article/954cf49938894b38a012228bbd1f27e1
Autor:
Arnold Hayer, Upinder S Bhalla
Publikováno v:
PLoS Computational Biology, Vol 1, Iss 2, Pp 137-154 (2005)
Changes in the synaptic connection strengths between neurons are believed to play a role in memory formation. An important mechanism for changing synaptic strength is through movement of neurotransmitter receptors and regulatory proteins to and from
Externí odkaz:
https://doaj.org/article/2f903ec1bf5344e0abdeb2949c85aea6
Autor:
Tobias Meyer, Anjali Bisaria, Damien Garbett, Changsong Yang, W. E. Moerner, Dannielle G. McCarthy, Tatyana Svitkina, Arnold Hayer
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-18 (2020)
Nature Communications
Nature Communications
Migrating cells move across diverse assemblies of extracellular matrix (ECM) that can be separated by micron-scale gaps. For membranes to protrude and reattach across a gap, actin filaments, which are relatively weak as single filaments, must polymer
Autor:
Huashan Peng, Carl Ernst, Blandine Ponroy Bally, Jacques Drouin, Emma V. Jones, Selin Jessa, Alexandre Mayran, Keith K. Murai, W. Todd Farmer, Arnold Hayer, J. Benjamin Kacerovsky, Julie L. Lefebvre
Publikováno v:
Hum Mol Genet
Down syndrome (DS), caused by the triplication of human chromosome 21, leads to significant alterations in brain development and is a major genetic cause of intellectual disability. While much is known about changes to neurons in DS, the effects of t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08a00e1878a8aa86986c0cd505c8c012
https://europepmc.org/articles/PMC7104679/
https://europepmc.org/articles/PMC7104679/
Publikováno v:
Science
Actin cortex controls cell migration Cell migration is mainly controlled by local actin polymerization–driven membrane protrusion. However, a second structural mechanism might also regulate membrane protrusions and directed migration: changes in th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d781fe0d76ffb2f7a522378305ab1abd
Autor:
Kimberle Shen, Kyuho Han, Lin Gan, Jerry R Lin, Xuecai Ge, Akiko Seki, Arnold Hayer, William S. Talbot, Harini Iyer, Tobias Meyer, Roy Wollman, Gautam Dey
Publikováno v:
Nature cell biology
Nature cell biology, vol 21, iss 5
Gan, Lin; Seki, Akiko; Shen, Kimberle; Iyer, Harini; Han, Kyuho; Hayer, Arnold; et al.(2019). The lysosomal GPCR-like protein GPR137B regulates Rag and mTORC1 localization and activity.. Nature cell biology, 21(5), 614-626. doi: 10.1038/s41556-019-0321-6. UCLA: Retrieved from: http://www.escholarship.org/uc/item/9vn885p1
Nature cell biology, vol 21, iss 5
Gan, Lin; Seki, Akiko; Shen, Kimberle; Iyer, Harini; Han, Kyuho; Hayer, Arnold; et al.(2019). The lysosomal GPCR-like protein GPR137B regulates Rag and mTORC1 localization and activity.. Nature cell biology, 21(5), 614-626. doi: 10.1038/s41556-019-0321-6. UCLA: Retrieved from: http://www.escholarship.org/uc/item/9vn885p1
Cell growth is controlled by a lysosomal signalling complex containing Rag small GTPases and mammalian target of rapamycin complex 1 (mTORC1) kinase. Here, we carried out a microscopy-based genome-wide human short interfering RNA screen and discovere
Autor:
Roberta Mancini, Jürgen Kartenbeck, Ari Helenius, Fabian Herzog, Sabrina Engel, Thomas Heger, Arnold Hayer
After binding to its cell surface receptor ganglioside GM1, simian virus 40 (SV40) is endocytosed by lipid raft-mediated endocytosis and slowly transported to the endoplasmic reticulum, where partial uncoating occurs. We analyzed the intracellular pa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ca656d1a8baec4fa652acf5e6eb4a15
https://europepmc.org/articles/PMC5625483/
https://europepmc.org/articles/PMC5625483/
Autor:
Feng-Chiao Tsai, Mingyu Chung, Arnold Hayer, Lin Shao, Anjali Bisaria, Eric Betzig, Hee Won Yang, Tobias Meyer, Lydia-Marie Joubert
The development and maintenance of tissues requires collective cell movement, during which neighbouring cells coordinate the polarity of their migration machineries. Here, we ask how polarity signals are transmitted from one cell to another across sy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea4a6d7d9491b72632581269f9f6d44e
https://europepmc.org/articles/PMC6159904/
https://europepmc.org/articles/PMC6159904/
Publikováno v:
PLoS Pathogens, Vol 12, Iss 5, p e1005603 (2016)
PLoS Pathogens
PLoS Pathogens
Vascular endothelial cells act as gatekeepers that protect underlying tissue from blood-borne toxins and pathogens. Nevertheless, endothelial cells are able to internalize large fibrin clots and apoptotic debris from the bloodstream, although the pre