Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Arnold Han"'
Autor:
Kazuya Masuda, Adam Kornberg, Jonathan Miller, Sijie Lin, Nathan Suek, Theo Botella, Kerim A. Secener, Alyssa M. Bacarella, Liang Cheng, Matthew Ingham, Vilma Rosario, Ahmed M. Al-Mazrou, Steven A. Lee-Kong, Ravi P. Kiran, Marlon Stoeckius, Peter Smibert, Armando Del Portillo, Paul E. Oberstein, Peter A. Sims, Kelley S. Yan, Arnold Han
Publikováno v:
JCI Insight, Vol 7, Iss 7 (2022)
Clinical outcomes in colorectal cancer (CRC) correlate with T cell infiltrates, but the specific contributions of heterogenous T cell types remain unclear. To investigate the diverse function of T cells in CRC, we profiled 37,931 T cells from tumors
Externí odkaz:
https://doaj.org/article/a994919d65984adfb8344af434a112be
Autor:
Yang Li, Nato Teteloshvili, Shulian Tan, Samhita Rao, Arnold Han, Yong-Guang Yang, Rémi J. Creusot
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Thymic selection constitutes the first checkpoint in T-cell development to purge autoreactive T cells. Most of our understanding of this process comes from animal models because of the challenges of studying thymopoiesis and how T cell receptor (TCR)
Externí odkaz:
https://doaj.org/article/938c9ed0d6074e4799ab4abc2719510e
Table S1: Patient characteristics Table S2: Cell culture medium Table S3: FACS reagents Table S4A: Primers for RT PCR and amplification Table S4B: DNA barcodes Table S5: Immunoglobulin junction sequences that were detected in at least two cells per s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::345270069bb79846be8cf7fbd101997c
https://doi.org/10.1158/2326-6066.22539227
https://doi.org/10.1158/2326-6066.22539227
Multiple myeloma is characterized by the clonal expansion of malignant plasma cells in the bone marrow. But the phenotypic diversity and the contribution of less predominant B-lineage clones to the biology of this disease have been controversial. Her
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a934ce80f67597127791da893f6d61c3
https://doi.org/10.1158/2326-6066.c.6549026.v1
https://doi.org/10.1158/2326-6066.c.6549026.v1
Autor:
Jay H. Lefkowitch, Samuel F. Bakhoum, George A. Alba, Denis Schapiro, Yaron Bram, Patricia Ho, Ajay Nair, Anjali Saqi, Yiping Wang, Robert E. Schwartz, Daniel T. Montoro, Armando Del Portillo, Jianwen Que, Alain C. Borczuk, Robert F. Schwabe, Sean W. Chen, André F. Rendeiro, Johannes C. Melms, Somnath Tagore, Hanina Hibshoosh, Adrienne M. Luoma, Adam E. Kornberg, Amit Dipak Amin, Mariano G. Clausi, Niroshana Anandasabapathy, Chris J. Frangieh, Stephen M. Lagana, Olivier Elemento, Yinshan Fang, Huachao Huang, Igor Katsyv, Mayte Suárez-Fariñas, Xinzheng V. Guo, Benjamin Izar, Emily J. Tsai, Charles C. Marboe, Mathieu F. Bakhoum, Aveline Filliol, Glen S. Markowitz, Hiranmayi Ravichandran, Arnold Han, Emmanuel Zorn, Meri Rogava, Jana Biermann
Publikováno v:
Nature. 595:114-119
Respiratory failure is the leading cause of death in patients with severe SARS-CoV-2 infection1,2, but the host response at the lung tissue level is poorly understood. Here we performed single-nucleus RNA sequencing of about 116,000 nuclei from the l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cefac8d5d3925263c7f2ffbb4292f5c1
https://doi.org/10.1038/s41586-021-03569-1
https://doi.org/10.1038/s41586-021-03569-1
Autor:
Samhita Rao, Aleksandar Obradovic, Karim Gharib, Adam Kornberg, Theo Botella, Christine Moon, Ali Ghasemzadeh, Sijie Lin, Izabela Krupska, Erin Bush, Alan J. Korman, Kelley S. Yan, Charles G. Drake, Andrea Califano, Arnold Han
Publikováno v:
SSRN Electronic Journal.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a9503e395fad4233f5c912cbc3e6b537
https://doi.org/10.2139/ssrn.4144960
https://doi.org/10.2139/ssrn.4144960
Autor:
Gwennaëlle C. Monnot, Marcin Wegrecki, Tan-Yun Cheng, Yi-Ling Chen, Brigitte N. Sallee, Reka Chakravarthy, Ioanna Maria Karantza, Shin Yi Tin, Alexandra E. Khaleel, Isha Monga, Laura N. Uwakwe, Alice Tillman, Bin Cheng, Soundos Youssef, Soo Weei Ng, Adam Shahine, Javier A. Garcia-Vilas, Anne-Catrin Uhlemann, Lindsey A. Bordone, Arnold Han, Christine H. Rohde, Graham Ogg, D. Branch Moody, Jamie Rossjohn, Annemieke de Jong
Publikováno v:
Nature immunology. 24(1)
Expressed on epidermal Langerhans cells, CD1a presents a range of self-lipid antigens found within the skin; however, the extent to which CD1a presents microbial ligands from bacteria colonizing the skin is unclear. Here we identified CD1a-dependent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39a86740b532fc2ec91dcbf40e12ba11
https://pubmed.ncbi.nlm.nih.gov/36550321
https://pubmed.ncbi.nlm.nih.gov/36550321
Autor:
Michael M. Givertz, Mohsen Khosravi-Maharlooei, Sijie Lin, Megan Sykes, Maryjane Farr, Yoshifumi Naka, Marlena V. Habal, Charles C. Marboe, Siu-hong Ho, Arnold Han, Koji Takeda, Aleksandar Obradovic, Poulomi Roy, Sarah See, Susan Restaino, Emmanuel Zorn, Linda J. Addonizio, April M.I Miller, Donna M. Mancini, Shihab Ronzon, Samhita Rao, Joren C. Madsen
Publikováno v:
Am J Transplant
T cells are implicated in the pathogenesis of cardiac allograft vasculopathy (CAV), yet their clonality, specificity, and function are incompletely defined. Here we used T cell receptor β chain (TCRB) sequencing to study the T cell repertoire in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b7e15d32a4fcbfb2482379011e7877e
https://europepmc.org/articles/PMC8672660/
https://europepmc.org/articles/PMC8672660/
Autor:
Marlon Stoeckius, Kelley S. Yan, Vilma L. Rosario, Kerim Secener, Kazuya Masuda, Arnold Han, Nathan Suek, P. Ravi Kiran, Matthew Ingham, Ahmed M. Al-Masrou, Peter A. Sims, Adam E. Kornberg, Paul E. Oberstein, Peter Smibert, Sijie Lin, Patricia Ho, Alyssa M. Bacarella, Steven A. Lee-Kong
Although degree of T-cell infiltration in CRC was shown to correlate with a positive prognosis, the contribution of phenotypically and functionally distinct T cell subtypes within tumors remains unclear. We analyzed 37,931 single T cells with respect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6a11befa3e827ce5ab45715c7faac24c
https://doi.org/10.1101/2020.09.27.313445
https://doi.org/10.1101/2020.09.27.313445
Publikováno v:
Cancer Immunology Research. 5:744-754
Multiple myeloma is characterized by the clonal expansion of malignant plasma cells in the bone marrow. But the phenotypic diversity and the contribution of less predominant B-lineage clones to the biology of this disease have been controversial. Her
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0eac30ca19538beb8ea0da31e720012d
https://doi.org/10.1158/2326-6066.cir-17-0012
https://doi.org/10.1158/2326-6066.cir-17-0012