A chemoselective and continuous synthesis of m-sulfamoylbenzamide analogues

Autor: Arno Verlee, Thomas Heugebaert, Tom van der Meer, Pavel I. Kerchev, Frank Van Breusegem, Christian V. Stevens

Publikováno v: Beilstein Journal of Organic Chemistry, Vol 13, Iss 1, Pp 303-312 (2017)

For the synthesis of m-sulfamoylbenzamide analogues, small molecules which are known for their bioactivity, a chemoselective procedure has been developed starting from m-(chlorosulfonyl)benzoyl chloride. Although a chemoselective process in batch was

Externí odkaz: https://doaj.org/article/0680057355e141569b9b2c1fa11aa8df

Gold and Palladium Mediated Bimetallic Catalysis: Mechanistic Investigation through the Isolation of the Organogold(I) Intermediates

Autor: Christian V. Stevens, Arno Verlee, Thomas S. A. Heugebaert, Tom van der Meer, Pavel Kerchev, Frank Van Breusegem, Kristof Van Hecke

Publikováno v: ACS Catalysis. 9:7862-7869

Au–Pd based catalytic systems are a unique couple due to the carbophilic Lewis acidity of Au and the redox properties of Pd. To gain more insight into this bimetallic couple, a synthetic and mechanistic investigation was conducted. As key substrate

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::98617e22eba8a1191a1856015d31094f
https://doi.org/10.1021/acscatal.9b02275

Domino reaction of a gold catalyzed 5-endo-dig cyclization and a [3,3]-sigmatropic rearrangement towards polysubstituted pyrazoles

Autor: Tom van der Meer, Thomas S. A. Heugebaert, Christian V. Stevens, Arno Verlee, Frank Van Breusegem, Pavel Kerchev

Publikováno v: Organic & Biomolecular Chemistry. 16:9359-9363

Pyrazoles are important heterocyclic compounds with a broad range of biological activities. A new procedure toward tri- or tetrasubstituted pyrazoles has been developed, via a one-pot gold catalyzed synthesis from hydrazines with alkynyl aldehydes or

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2dc763f9c967af06a9e7331841618e46
https://doi.org/10.1039/c8ob02807a

A chemoselective and continuous synthesis of m-sulfamoylbenzamide analogues

Autor: Christian V. Stevens, Thomas S. A. Heugebaert, Frank Van Breusegem, Pavel Kerchev, Tom van der Meer, Arno Verlee

Publikováno v: Beilstein Journal of Organic Chemistry
BEILSTEIN JOURNAL OF ORGANIC CHEMISTRY
Beilstein Journal of Organic Chemistry, Vol 13, Iss 1, Pp 303-312 (2017)

For the synthesis of m-sulfamoylbenzamide analogues, small molecules which are known for their bioactivity, a chemoselective procedure has been developed starting from m-(chlorosulfonyl)benzoyl chloride. Although a chemoselective process in batch was

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03c11d2e81d51df532b1f05e12c8142b
http://europepmc.org/articles/PMC5331323

Chemical Genetics Approach Identifies Abnormal Inflorescence Meristem 1 as a Putative Target of a Novel Sulfonamide That Protects Catalase2-Deficient Arabidopsis against Photorespiratory Stress

Autor: Kris Gevaert, Frank Van Breusegem, Arno Verlee, Patrick Willems, Francis Impens, Tom van der Meer, Pavel Kerchev, Christian V. Stevens, Christa Testerink

Publikováno v: Cells, Vol 9, Iss 2026, p 2026 (2020)
CELLS
Cells, 9(9)
Cells 9 (2020) 9
Cells
Volume 9
Issue 9

Alterations of hydrogen peroxide (H2O2) levels have a profound impact on numerous signaling cascades orchestrating plant growth, development, and stress signaling, including programmed cell death. To expand the repertoire of known molecular mechanism

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa2f018e1f6d03be49de0e165eaaa4de
https://doi.org/10.3390/cells9092026