Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Arno Meiler"'
Autor:
Arno Meiler, Fabio Marchiano, Margaux Haering, Manuela Weitkunat, Frank Schnorrer, Bianca H. Habermann
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-21 (2021)
Abstract Gene expression regulation requires precise transcriptional programs, led by transcription factors in combination with epigenetic events. Recent advances in epigenomic and transcriptomic techniques provided insight into different gene regula
Externí odkaz:
https://doaj.org/article/a2eb2811461c45ed9c47e31d8eb2f981
Autor:
Anna Gebhardt, Valter Bergant, Daniel Schnepf, Markus Moser, Arno Meiler, Dieudonnée Togbe, Claire Mackowiak, Line S Reinert, Søren R Paludan, Bernhard Ryffel, Alexey Stukalov, Peter Staeheli, Andreas Pichlmair
Publikováno v:
PLoS Pathogens, Vol 15, Iss 12, p e1008155 (2019)
Cellular response to environmental challenges requires immediate and precise regulation of transcriptional programs. During viral infections, this includes the expression of antiviral genes that are essential to combat the pathogen. Transcribed mRNAs
Externí odkaz:
https://doaj.org/article/2f2f0378c45148fa99debb5c174e921a
Autor:
Darya A Haas, Arno Meiler, Katharina Geiger, Carola Vogt, Ellen Preuss, Georg Kochs, Andreas Pichlmair
Publikováno v:
PLoS Pathogens, Vol 14, Iss 4, p e1006980 (2018)
Viruses have evolved a plethora of mechanisms to target host antiviral responses. Here, we propose a yet uncharacterized mechanism of immune regulation by the orthomyxovirus Thogoto virus (THOV) ML protein through engaging general transcription facto
Externí odkaz:
https://doaj.org/article/d852e5cafdbf431884afa034fc22b015
Autor:
Bärbel Edelmann-Stephan, Andreas Hochhaus, Sabine Brandt, Nicolas Schröder, Florian Perner, Gurumoorthy Krishnamoorthy, Iain Coldham, Amit U. Sinha, Claudia Waskow, Lars Bullinger, Stefanie Jilg, Philipp J. Jost, Martin Ungelenk, Francesca Palandri, Matthias Mann, Rebecca Austin, Frank Edlich, Tina M. Schnöder, Susann Rahmig, Carolin Herzog, Robert Zeiser, Steven W. Lane, Arno Meiler, Thomas Ernst, Christian A. Hübner, Juliane Mohr, Ashok Kumar Jayavelu, Peter R. Mertens, Nicolas Huber, Florian H. Heidel, Ann Mullally, Berend Isermann
Publikováno v:
Nature
Janus kinases (JAKs) mediate responses to cytokines, hormones and growth factors in haematopoietic cells1,2. The JAK gene JAK2 is frequently mutated in the ageing haematopoietic system3,4 and in haematopoietic cancers5. JAK2 mutations constitutively
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f442066b883a233ae9eb4a8963b42d0e
https://doi.org/10.1038/s41586-020-2968-3
https://doi.org/10.1038/s41586-020-2968-3
Gene expression regulation requires precise transcriptional programs, led by transcription factors in combination with epigenetic events. Recent advances in epigenomic and transcriptomic techniques provided insight into different gene regulation mech
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b244c2176b8d668f96e51807f8e62826
https://doi.org/10.1101/2021.01.28.428613
https://doi.org/10.1101/2021.01.28.428613
Autor:
Dieudonnée Togbe, Peter Staeheli, Line S. Reinert, Alexey Stukalov, Andreas Pichlmair, Arno Meiler, Valter Bergant, Bernhard Ryffel, Claire Mackowiak, Daniel Schnepf, Markus Moser, Søren R. Paludan, Anna Gebhardt
Publikováno v:
PLOS Pathogens
Gebhardt, A, Bergant, V, Schnepf, D, Moser, M, Meiler, A, Togbe, D, Mackowiak, C, Reinert, L, Paludan, S R, Ryffel, B, Stukalov, A, Staeheli, P & Pichlmair, A 2019, ' The alternative cap-binding complex is required for antiviral defense in vivo ', PLOS Pathogens, vol. 15, no. 12, 1008155 . https://doi.org/10.1371/journal.ppat.1008155
PLOS PATHOGENS
PLoS Pathogens, Vol 15, Iss 12, p e1008155 (2019)
PLoS Pathogens
PLoS Pathogens, Public Library of Science, 2019, 15 (12), pp.e1008155. ⟨10.1371/journal.ppat.1008155⟩
Gebhardt, A, Bergant, V, Schnepf, D, Moser, M, Meiler, A, Togbe, D, Mackowiak, C, Reinert, L, Paludan, S R, Ryffel, B, Stukalov, A, Staeheli, P & Pichlmair, A 2019, ' The alternative cap-binding complex is required for antiviral defense in vivo ', PLOS Pathogens, vol. 15, no. 12, 1008155 . https://doi.org/10.1371/journal.ppat.1008155
PLOS PATHOGENS
PLoS Pathogens, Vol 15, Iss 12, p e1008155 (2019)
PLoS Pathogens
PLoS Pathogens, Public Library of Science, 2019, 15 (12), pp.e1008155. ⟨10.1371/journal.ppat.1008155⟩
Cellular response to environmental challenges requires immediate and precise regulation of transcriptional programs. During viral infections, this includes the expression of antiviral genes that are essential to combat the pathogen. Transcribed mRNAs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df12237580e53b456b64204955e154d9
Autor:
Arif Mohammed, Marc Wirth, Helmut Blum, Sigrun Schmähling, Lars Israel, Katja Finkl, Ji-Joon Song, Yoonjung Lee, Katharina Tauscher, Bianca Habermann, Arno Meiler, Jürg Müller, Julia Philippou-Massier, Axel Imhof
Publikováno v:
Development (Cambridge, England)
Development
Development (Cambridge, England), Company of Biologists, 2018, 145 (7), pp.dev163808. ⟨10.1242/dev.163808⟩
Development (Cambridge, England), Company of Biologists, 2018, 145 (7), pp.163808. ⟨10.1242/dev.163808⟩
Development
Development (Cambridge, England), Company of Biologists, 2018, 145 (7), pp.dev163808. ⟨10.1242/dev.163808⟩
Development (Cambridge, England), Company of Biologists, 2018, 145 (7), pp.163808. ⟨10.1242/dev.163808⟩
The Drosophila Ash1 protein is a trithorax-group (trxG) regulator that antagonizes Polycomb repression at HOX genes. Ash1 di-methylates lysine 36 in histone H3 (H3K36me2) but how this activity is controlled and at which genes it functions is not well
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df4beeea705d6a210a553ebba4ea02a0
http://europepmc.org/articles/PMC5963871
http://europepmc.org/articles/PMC5963871
Autor:
Andreas Pichlmair, Katharina Geiger, Arno Meiler, Georg Kochs, Darya A. Haas, Carola Vogt, Ellen Preuss
Publikováno v:
PLoS Pathogens
PLoS Pathogens, Vol 14, Iss 4, p e1006980 (2018)
PLoS Pathogens, Vol 14, Iss 4, p e1006980 (2018)
Viruses have evolved a plethora of mechanisms to target host antiviral responses. Here, we propose a yet uncharacterized mechanism of immune regulation by the orthomyxovirus Thogoto virus (THOV) ML protein through engaging general transcription facto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a362430b686285bc6af6613d80f7ab0d
http://europepmc.org/articles/PMC5927403
http://europepmc.org/articles/PMC5927403
Autor:
Matthias Habjan, Christian Benda, Andreas Pichlmair, Marco Y. Hein, Angelika Mann, Arno Meiler, Darya A. Haas, Bianca Habermann, Anna Gebhardt, Matthias Mann
Publikováno v:
Nature Communications
NATURE COMMUNICATIONS
NATURE COMMUNICATIONS
The flow of genetic information from DNA to protein requires polymerase-II-transcribed RNA characterized by the presence of a 5′-cap. The cap-binding complex (CBC), consisting of the nuclear cap-binding protein (NCBP) 2 and its adaptor NCBP1, is be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7a9c02425266ce03d8a06760c7d00c2
http://europepmc.org/articles/PMC4595607
http://europepmc.org/articles/PMC4595607
Publikováno v:
BMC Bioinformatics, Vol 13, Iss 1, p 223 (2012)
BMC Bioinformatics
BMC Bioinformatics
Background The COG database is the most popular collection of orthologous proteins from many different completely sequenced microbial genomes. Per definition, a cluster of orthologous groups (COG) within this database exclusively contains proteins th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6746b4ed31cb9edb859a6db1f4d6e4c3
https://doi.org/10.1186/1471-2105-13-223
https://doi.org/10.1186/1471-2105-13-223