Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Arno F Alpi"'
Autor:
Dawafuti Sherpa, Judith Mueller, Özge Karayel, Peng Xu, Yu Yao, Jakub Chrustowicz, Karthik V Gottemukkala, Christine Baumann, Annette Gross, Oliver Czarnecki, Wei Zhang, Jun Gu, Johan Nilvebrant, Sachdev S Sidhu, Peter J Murray, Matthias Mann, Mitchell J Weiss, Brenda A Schulman, Arno F Alpi
Publikováno v:
eLife, Vol 11 (2022)
The development of haematopoietic stem cells into mature erythrocytes – erythropoiesis – is a controlled process characterized by cellular reorganization and drastic reshaping of the proteome landscape. Failure of ordered erythropoiesis is associ
Externí odkaz:
https://doaj.org/article/34cf5cd0625f4e91870c6fb2f280211e
Autor:
Özge Karayel, Peng Xu, Isabell Bludau, Senthil Velan Bhoopalan, Yu Yao, Freitas Colaco Ana Rita, Alberto Santos, Brenda A Schulman, Arno F Alpi, Mitchell J Weiss, Matthias Mann
Publikováno v:
Molecular Systems Biology, Vol 16, Iss 12, Pp n/a-n/a (2020)
Abstract Human erythropoiesis is an exquisitely controlled multistep developmental process, and its dysregulation leads to numerous human diseases. Transcriptome and epigenome studies provided insights into system‐wide regulation, but we currently
Externí odkaz:
https://doaj.org/article/f2d224febe78406ba48cdd980a4aa440
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e60071 (2013)
The Fanconi anemia (FA) pathway recognizes interstrand DNA crosslinks (ICLs) and contributes to their conversion into double-strand DNA breaks, which can be repaired by homologous recombination. Seven orthologs of the 15 proteins associated with Fanc
Externí odkaz:
https://doaj.org/article/2e0878428fe4428591b1af4799ef4b68
Publikováno v:
PLoS ONE, Vol 7, Iss 5, p e36970 (2012)
The many proteins that function in the Fanconi anaemia (FA) monoubiquitylation pathway initiate replicative DNA crosslink repair. However, it is not clear whether individual FA genes participate in DNA repair pathways other than homologous recombinat
Externí odkaz:
https://doaj.org/article/591308a5da0d441b86b6059e5a89f409
Autor:
Arno F. Alpi, Ronald T. Hay, Gareth J. Inman, Amit Garg, Adel F.M. Ibrahim, Eilís Carroll, Craig MacKay
XLSX file - 196KB, Excel file with siRNA screen data.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0d93ba22ef08127b65059420acf0caa
https://doi.org/10.1158/0008-5472.22402478.v1
https://doi.org/10.1158/0008-5472.22402478.v1
Autor:
Arno F. Alpi, Ronald T. Hay, Gareth J. Inman, Amit Garg, Adel F.M. Ibrahim, Eilís Carroll, Craig MacKay
PDF file - 1462KB, Fig. S1: HOIP depletion results in cisplatin hypersensitivity. Fig. S2: HOIP depletion sensitizes cells to genotoxin-induced apoptotic cell death. Fig. S3: HEK293 cells stably expressing HA-IκBα S32A;S36A. Fig. S4: Boxplot analys
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9a164d6b3452a2b9819add98cb91322
https://doi.org/10.1158/0008-5472.22402481
https://doi.org/10.1158/0008-5472.22402481
Autor:
Peng Xu, Özge Karayel, Judith Mueller, Dawafuti Sherpa, Yu Yao, Jakub Chrustowicz, Karthik V Gottemukkala, Christine Baumann, Annette Gross, Oliver Czarnecki, Wei Zhang, Jun Gu, Johan Nilvebrant, Sachdev S Sidhu, Peter J Murray, Matthias Mann, Mitchell J Weiss, Brenda A Schulman, Arno F Alpi
Publikováno v:
eLife. 11
The development of haematopoietic stem cells into mature erythrocytes – erythropoiesis – is a controlled process characterized by cellular reorganization and drastic reshaping of the proteome landscape. Failure of ordered erythropoiesis is associ
Autor:
Peng Xu, Özge Karayel, Judith Mueller, Dawafuti Sherpa, Yu Yao, Jakub Chrustowicz, Karthik V Gottemukkala, Christine Baumann, Annette Gross, Oliver Czarnecki, Wei Zhang, Jun Gu, Johan Nilvebrant, Sachdev S Sidhu, Peter J Murray, Matthias Mann, Mitchell J Weiss, Brenda A Schulman, Arno F Alpi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bf85976e13a84706594ac7dee56ecb67
https://doi.org/10.7554/elife.77937.sa2
https://doi.org/10.7554/elife.77937.sa2
Autor:
Dawafuti Sherpa, Judith Müller, Özge Karayel, Jakub Chrustowicz, Peng Xu, Karthik V. Gottemukkala, Christine Baumann, Annette Gross, Oliver Czarnezki, Wei Zhang, Jun Gu, Johan Nilvebrant, Mitchell J. Weiss, Sachdev S. Sidhu, Peter J. Murray, Matthias Mann, Brenda A. Schulman, Arno F. Alpi
The development of haematopoietic stem cells into mature erythrocytes – erythropoiesis – is a controlled process characterized by cellular reorganisation and drastic reshaping of the proteome landscape. Failure of ordered erythropoiesis is associ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a2ce5d94c084b7c50dd578431d2d5826
https://doi.org/10.1101/2022.01.18.476717
https://doi.org/10.1101/2022.01.18.476717
Publikováno v:
EMBO Reports
The ubiquitin system is an important part of the host cellular defense program during bacterial infection. This is in particular evident for a number of bacteria including Salmonella Typhimurium and Mycobacterium tuberculosis which—inventively as p