Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Arnita, Barnes"'
Autor:
Andrew Dippel, Austin Gallegos, Vineela Aleti, Arnita Barnes, Xiaoru Chen, Elizabeth Christian, Jared Delmar, Qun Du, Reza Esfandiary, Erika Farmer, Andrew Garcia, Qing Li, Jia Lin, Weiyi Liu, LeeAnn Machiesky, Neil Mody, Arun Parupudi, Meagan Prophet, Keith Rickert, Kim Rosenthal, Song Ren, Harini Shandilya, Reena Varkey, Kevin Wons, Yuling Wu, Yueh-Ming Loo, Mark T. Esser, Nicole L. Kallewaard, Sarav Rajan, Melissa Damschroder, Weichen Xu, Gilad Kaplan
Publikováno v:
mAbs, Vol 15, Iss 1 (2023)
ABSTRACTTo combat the COVID-19 pandemic, potential therapies have been developed and moved into clinical trials at an unprecedented pace. Some of the most promising therapies are neutralizing antibodies against SARS-CoV-2. In order to maximize the th
Externí odkaz:
https://doaj.org/article/9f5679dc1264437881b543ce3007dd81
Autor:
Andrew Dippel, Austin Gallegos, Vineela Aleti, Arnita Barnes, Xiaoru Chen, Elizabeth Christian, Jared Delmar, Qun Du, Reza Esfandiary, Erika Farmer, Andrew Garcia, Qing Li, Jia Lin, Weiyi Liu, LeeAnn Machiesky, Neil Mody, Arun Parupudi, Meagan Prophet, Keith Rickert, Kim Rosenthal, Song Ren, Harini Shandilya, Reena Varkey, Kevin Wons, Yuling Wu, Yueh-Ming Loo, Mark T. Esser, Nicole L. Kallewaard, Sarav Rajan, Melissa Damschroder, Weichen Xu, Gilad Kaplan
Publikováno v:
mAbs. 15(1)
To combat the COVID-19 pandemic, potential therapies have been developed and moved into clinical trials at an unprecedented pace. Some of the most promising therapies are neutralizing antibodies against SARS-CoV-2. In order to maximize the therapeuti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af952b124fb9afa4945e1f0ae2458177
https://pubmed.ncbi.nlm.nih.gov/36476037
https://pubmed.ncbi.nlm.nih.gov/36476037
Autor:
Norman C. Peterson, Jason White, Keith W Rickert, M. Jack Borrok, Kevin L Allen, William Dall'acqua, Lu Shan, Ping Tsui, Kyle Kuszpit, Richard N. Hanna, Qing Li, Arnita Barnes, Herren Wu
Publikováno v:
Molecular Pharmaceutics.
Targeted strategies to deliver and retain drugs to kidneys are needed to improve drug accumulation and efficacy in a myriad of kidney diseases. These drug delivery systems show potential for improving the therapeutic windows of drugs acting in the ki
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0b40c2786c81a544dd2d2842429b7bf7
https://doi.org/10.1021/acs.molpharmaceut.9b00939
https://doi.org/10.1021/acs.molpharmaceut.9b00939
Autor:
Qing, Li, Norman, Peterson, Richard N, Hanna, Kyle, Kuszpit, Jason, White, Kevin L, Allen, Arnita, Barnes, Keith W, Rickert, Lu, Shan, Herren, Wu, William F, Dall'Acqua, Ping, Tsui, M Jack, Borrok
Publikováno v:
Molecular pharmaceutics. 17(2)
Targeted strategies to deliver and retain drugs to kidneys are needed to improve drug accumulation and efficacy in a myriad of kidney diseases. These drug delivery systems show potential for improving the therapeutic windows of drugs acting in the ki
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::75db3937acf4248ee8829b3cfa9c3bf5
https://pubmed.ncbi.nlm.nih.gov/31841002
https://pubmed.ncbi.nlm.nih.gov/31841002
Autor:
Arnita Barnes, Herren Wu, Hui Feng, Shu Zhang, Raghothama Chaerkady, Gargi Roy, Jie Zhu, Thomas D. Martin, Diane Hatton, Michael A. Bowen, Lina Li, Rod Brian Jimenez, Megan Rice, Marcello Marelli, Jihong Wang
Publikováno v:
mAbs
The conserved glycosylation site Asn297 of a monoclonal antibody (mAb) can be decorated with a variety of sugars that can alter mAb pharmacokinetics and recruitment of effector proteins. Antibodies lacking the core fucose at Asn297 (afucosylated mAbs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6789460f1fa27218fc536523c94a86b
http://europepmc.org/articles/PMC5916560
http://europepmc.org/articles/PMC5916560
Autor:
Daniel R. Higazi, Michael A. Bowen, Nicholas J. Bond, Rebecca Dunmore, Lynne Murray, William Dall'acqua, Yanli Wu, Jie Zhu, Toyin Kasali, M. Jack Borrok, Lena Shirinian, Arnita Barnes, Catherine Huntington, Sandrina Phipps, John Hood, Emilie Solier, Ping Tsui, Keith W Rickert, Alan M. Carruthers
Publikováno v:
mAbs. 9:104-113
Excessive transforming growth factor (TGF)-β is associated with pro-fibrotic responses in lung disease, yet it also plays essential roles in tissue homeostasis and autoimmunity. Therefore, selective inhibition of excessive and aberrant integrin-medi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d570ca136c988614413eb835598fa70
https://doi.org/10.1080/19420862.2016.1255390
https://doi.org/10.1080/19420862.2016.1255390
Autor:
Anthony Shannon, Arnita Barnes, Susan Wilson, Caroline Kittinger, Ellen O'Connor, Robert Stadelman, Sandrina Phipps, Alan K. Hunter, LeeAnn Machiesky
Publikováno v:
Protein Expression and Purification. 167:105528
Interferon-alpha receptor 1 (IFNAR1) is a target of interest for recombinant biotherapeutics that block the JAK/STAT pathway. This pathway is believed to play a role in many diseases including Hepatitis B and C, Herpes Simplex, Multiple Sclerosis, an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::010b23d0fc456a8b5fdafd0a3e5b803b
https://doi.org/10.1016/j.pep.2019.105528
https://doi.org/10.1016/j.pep.2019.105528
Autor:
Ryan N. Gilbreth, Luba Grinberg, Vaheh Oganesyan, Hamza Amdouni, Shabazz Novarra, Arnita Barnes, Manuel Baca
Publikováno v:
The Journal of biological chemistry. 293(25)
4-1BBL is a member of the tumor necrosis factor (TNF) superfamily and is the ligand for the TNFR superfamily receptor, 4-1BB. 4-1BB plays an immunomodulatory role in T cells and NK cells, and agonists of this receptor have garnered strong attention a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b32434c45193111c589f7c69470a431d
https://pubmed.ncbi.nlm.nih.gov/29720399
https://pubmed.ncbi.nlm.nih.gov/29720399
Autor:
Sandrina Phipps, Michael P. McCarthy, Ruchi Gupta, William Dall'acqua, Ping Tsui, Kristen Lekstrom, Arnita Barnes, Herren Wu, Antonio DiGiandomenico, M. Jack Borrok, Gabriela M. Marchetti, Nurten Beyaz
Publikováno v:
JCI insight. 3(12)
IgG antibodies are abundantly present in the vasculature but to a much lesser extent in mucosal tissues. This contrasts with antibodies of the IgA and IgM isotype that are present at high concentration in mucosal secretions due to active delivery by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc978b9893d359aa22d61d3de6cbef7d
https://pubmed.ncbi.nlm.nih.gov/29925682
https://pubmed.ncbi.nlm.nih.gov/29925682
Autor:
William Dall'acqua, Christine Tkaczyk, Arnita Barnes, Herren Wu, Andrew D. Ferguson, Vaheh Oganesyan
Publikováno v:
Acta Crystallographica Section F Structural Biology and Crystallization Communications. 69:302-305
Staphylococcus aureus alpha toxin (AT) has been crystallized in complex with the Fab fragment of a human antibody (MEDI4893). This constitutes the first reported crystals of AT bound to an antibody. The monoclinic crystals belonged to space group P21
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d682ee48ca1d0a3bf967e91fd2630b31
https://doi.org/10.1107/s1744309113002881
https://doi.org/10.1107/s1744309113002881