Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Arne Matteo Jörgensen"'
Autor:
Giuseppe Francesco, Racaniello, Patrick, Knoll, Arne Matteo, Jörgensen, Ilaria, Arduino, Valentino, Laquintana, Angela Assunta, Lopedota, Andreas, Bernkop-Schnürch, Nunzio, Denora
Publikováno v:
European Journal of Pharmaceutics and Biopharmaceutics. 179:95-104
The aim of this study was to develop thiolated self-emulsifying drug delivery systems (SEDDS) and nanostructured lipid carriers (NLCs) with improved mucoadhesive properties. Two non-ionic surfactants bearing a short and long PEG chain, namely polyoxy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4afeda9fcc6f45687b972a89253754d
https://doi.org/10.1016/j.ejpb.2022.08.015
https://doi.org/10.1016/j.ejpb.2022.08.015
Publikováno v:
Small (Weinheim an der Bergstrasse, Germany).
Cationic and ionizable cationic lipids are broadly applied as auxiliary agents, but their use is associated with adverse effects. If these excipients are rapidly degraded to endogenously occurring metabolites such as amino acids and fatty acids, thei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6af78ccf623ebaac9d672a1fc47fdd7
https://pubmed.ncbi.nlm.nih.gov/36610004
https://pubmed.ncbi.nlm.nih.gov/36610004
Autor:
Arne Matteo Jörgensen, Patrick Knoll, Soheil Haddadzadegan, Hannah Fabian, Andrea Hupfauf, Ronald Gust, Rainer Georg Jörgensen, Andreas Bernkop-Schnürch
Publikováno v:
International journal of pharmaceutics. 630
The aim of this study was to evaluate the safety and efficacy for hydrophobic ion-pairing of surfactants based on arginine (Arg). The prepared Arg-cholesteryl ester (ACE) and Arg-diosgenyl ester (ADE) were characterized regarding solubility, pKa, cri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37b89147b41de202c0c640dd63a309c5
https://pubmed.ncbi.nlm.nih.gov/36464112
https://pubmed.ncbi.nlm.nih.gov/36464112
Autor:
Doris E. Braun, Bao Le-Vinh, Julian David Friedl, Andreas Bernkop-Schnürch, Martina Tribus, Arne Matteo Jörgensen
Publikováno v:
Journal of Colloid and Interface Science. 584:684-697
Four solidification methods for self-emulsifying drug delivery systems (SEDDS) were compared to evaluate the impact of solidification on storage stability of an incorporated protein. Papain was loaded in SEDDS via hydrophobic ion pairing (HIP). Liqui
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ed2c1fa18a926040f1caa4862467d7c
https://doi.org/10.1016/j.jcis.2020.11.051
https://doi.org/10.1016/j.jcis.2020.11.051
Autor:
Joseph Chamieh, Arne Matteo Jörgensen, Andreas Bernkop-Schnürch, Hervé Cottet, Richard Wibel, Julian David Friedl
Publikováno v:
Molecular Pharmaceutics
The aim of this study was to investigate the fate and the impact of cosolvents in self-emulsifying drug delivery systems (SEDDS). Three different SEDDS comprising the cosolvents DMSO (FD), ethanol (FE), and benzyl alcohol (FBA) as well as the corresp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2eae2a7a9eabff21fbb09f525673465
http://europepmc.org/articles/PMC7482394
http://europepmc.org/articles/PMC7482394
Autor:
Richard, Wibel, Arne Matteo, Jörgensen, Flavia, Laffleur, Helen, Spleis, Victor, Claus, Andreas, Bernkop-Schnürch
Publikováno v:
International Journal of Pharmaceutics. 631:122476
Hydrophobic ion pairing and subsequent incorporation into self-emulsifying drug delivery systems (SEDDS) is a promising strategy to orally deliver hydrophilic macromolecular drugs. Within this study, hydrophobic ion pairs (HIP) between salmon calcito
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed23e4b6b53e699ac984cd376eb23b01
https://doi.org/10.1016/j.ijpharm.2022.122476
https://doi.org/10.1016/j.ijpharm.2022.122476
Autor:
Julian David Friedl, Arne Matteo Jörgensen, Nguyet-Minh Nguyen Le, Christian Steinbring, Andreas Bernkop-Schnürch
Publikováno v:
International journal of pharmaceutics. 618
Evaluation of different polyhydroxy surfaces in SEDDS to overcome the limitations associated with conventional polyethylene glycol (PEG)-based SEDDS surfaces for intracellular drug delivery.Anionic, cationic and non-ionic polyglycerol- (PG-) and alky
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82c9f00079891a703456464144c2bb44
https://pubmed.ncbi.nlm.nih.gov/35304244
https://pubmed.ncbi.nlm.nih.gov/35304244
Autor:
Patrick Knoll, Andreas Bernkop-Schnürch, Arne Matteo Jörgensen, Christian Steinbring, Laurenz Hämmerle, Richard Wibel, Willi Salvenmoser, Doris E. Braun
Publikováno v:
Biomacromolecules
In the present study, chitosan (CS) was thiolated by introducing l-cysteine via amide bond formation. Free thiol groups were protected with highly reactive 6-mercaptonicotinic acid (6-MNA) and less-reactive l-cysteine, respectively, via thiol/disulfi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::524467dcd2a4fa3fa5fd3d24af2c20cc
https://pubmed.ncbi.nlm.nih.gov/34459197
https://pubmed.ncbi.nlm.nih.gov/34459197
Autor:
Barbara Matuszczak, Arne Matteo Jörgensen, Christian Steinbring, Helen Spleis, Julian Dominik Wolf, Andreas Bernkop-Schnürch, Markus Kurpiers
Publikováno v:
Journal of pharmaceutical sciences. 110(1)
Aim The aim of this study was to evaluate biodegradable cationic surfactants based on lysine. Methods Lysine was esterified with cholesterol, oleyl alcohol and 1-decanol resulting in cholesteryl lysinate (CL), oleyl lysinate (OL) and decyl lysinate (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::349a9d506e90514805b5f4569c7e4890
https://pubmed.ncbi.nlm.nih.gov/32758547
https://pubmed.ncbi.nlm.nih.gov/32758547