Transcriptomic profiling of porcine pluripotency identifies species-specific reprogramming requirements for culturing iPSCs

Autor: Mette Habekost, Arne Lund Jørgensen, Per Qvist, Mark Denham

Publikováno v: Stem Cell Research, Vol 41, Iss , Pp - (2019)

Porcine embryonic and induced pluripotent stem cells (ESCs; iPSCs) have proven difficult to derive and maintain in vitro. This may be due to inappropriate culturing conditions and incomplete activation of proper pluripotency networks. To this end, we

Externí odkaz: https://doaj.org/article/7504aa01febb4032a6ff21a2ae433ae3

Transcriptomic profiling of porcine pluripotency identifies species-specific reprogramming requirements for culturing iPSCs

Autor: Habekost, Mette, Jørgensen, Arne Lund, Qvist, Per, Denham, Mark

Publikováno v: In Stem Cell Research December 2019 41

Ufullstendige tannfrakturer: To kasus

Autor: Torgils Lægreid, Arne Lund

Publikováno v: Den norske tannlegeforenings Tidende. 132

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::332dd755e1fe4b73e6bbf6c9cd6ce232
https://doi.org/10.56373/2021-5-7

Directly Reprogrammed Neurons Express MAPT and APP Splice Variants Pertinent to Ageing and Neurodegeneration

Autor: Per Qvist, Arne Lund Jørgensen, Ida E. Holm, Mark Denham, Mette Habekost

Publikováno v: Habekost, M, Qvist, P, Denham, M, Holm, I E & Jørgensen, A L 2021, ' Directly Reprogrammed Neurons Express MAPT and APP Splice Variants Pertinent to Ageing and Neurodegeneration ', Molecular Neurobiology, vol. 58, no. 5, pp. 2075-2087 . https://doi.org/10.1007/s12035-020-02258-w
Molecular Neurobiology

Neurons produced by reprogramming of other cell types are used to study cellular mechanisms of age-related neurodegenerative diseases. To model Alzheimer’s disease and other tauopathies, it is essential that alternative splicing of the MAPT transcr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ff73e30ad5ebeae5ac6307f6f817ae7
https://pure.au.dk/portal/da/publications/directly-reprogrammed-neurons-express-mapt-and-app-splice-variants-pertinent-to-ageing-and-neurodegeneration(bd439746-0fed-4128-a295-3a23e3d461ab).html

Longitudinal biometal accumulation and Ca isotope composition of the Göttingen minipig brain

Autor: Frédéric Moynier, Simon Turner, Roger S. Chung, Arne Lund Jørgensen, Mette Habekost, Michael A. Antonelli, Brandon Mahan, Pierre Burckel

Publikováno v: Mahan, B, Antonelli, M A, Burckel, P, Turner, S, Chung, R, Habekost, M, Jørgensen, A L & Moynier, F 2020, ' Longitudinal biometal accumulation and Ca isotope composition of the Göttingen minipig brain ', Metallomics : integrated biometal science, vol. 12, no. 10, pp. 1585-1598 . https://doi.org/10.1039/d0mt00134a

Biometals play a critical role in both the healthy and diseased brain's functioning. They accumulate in the normal aging brain, and are inherent to neurodegenerative disorders and their associated pathologies. A prominent example of this is the brain

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34bf66f4645de15310288152c8642ba4
https://pure.au.dk/portal/da/publications/longitudinal-biometal-accumulation-and-ca-isotope-composition-of-the-goettingen-minipig-brain(a7467086-fba6-4147-872f-73ffcd129515).html