Zobrazeno 1 - 10
of 303
pro vyhledávání: '"Arne Lindqvist"'
Autor:
Irena Roci, Jeramie D. Watrous, Kim A. Lagerborg, Lorenzo Lafranchi, Arne Lindqvist, Mohit Jain, Roland Nilsson
Publikováno v:
Cell Reports, Vol 26, Iss 7, Pp 1691-1700.e5 (2019)
Summary: Alterations in cell-cycle regulation and cellular metabolism are associated with cancer transformation, and enzymes active in the committed cell-cycle phase may represent vulnerabilities of cancer cells. Here, we map metabolic events in the
Externí odkaz:
https://doaj.org/article/7b10a39363e0477dbac11342bc364153
Autor:
Eike-Benjamin Braune, Yat Long Tsoi, Yee Peng Phoon, Sebastian Landor, Helena Silva Cascales, Daniel Ramsköld, Qiaolin Deng, Arne Lindqvist, Xiaojun Lian, Cecilia Sahlgren, Shao-Bo Jin, Urban Lendahl
Publikováno v:
Stem Cell Reports, Vol 6, Iss 5, Pp 643-651 (2016)
Notch signaling is an important regulator of stem cell differentiation. All canonical Notch signaling is transmitted through the DNA-binding protein CSL, and hyperactivated Notch signaling is associated with tumor development; thus it may be anticipa
Externí odkaz:
https://doaj.org/article/27589c4550a849429ff87dd9d4307da5
Publikováno v:
Cells, Vol 9, Iss 9, p 2126 (2020)
Cells recovering from the G2/M DNA damage checkpoint rely more on Aurora A-PLK1 signaling than cells progressing through an unperturbed G2 phase, but the reason for this discrepancy is not known. Here, we devised a method based on a FRET reporter for
Externí odkaz:
https://doaj.org/article/32266436397145bc8973ff44ee1f8bbd
Autor:
Zi-Kang Xie, Qiu-Gang Zong, Chao Yue, Xu-Zhi Zhou, Zhi-Yang Liu, Jian-Sen He, Yi-Xin Hao, Chung-Sang Ng, Hui Zhang, Shu-Tao Yao, Craig Pollock, Guan Le, Robert Ergun, Per-Arne Lindqvist
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-8 (2024)
Abstract Turbulent energy dissipation is a fundamental process in plasma physics that has not been settled. It is generally believed that the turbulent energy is dissipated at electron scales leading to electron energization in magnetized plasmas. He
Externí odkaz:
https://doaj.org/article/bb90f34b4c7347e1bf7695a3a33636fd
Autor:
Kristian Jeppsson, Kristian K Carlborg, Ryuichiro Nakato, Davide G Berta, Ingrid Lilienthal, Takaharu Kanno, Arne Lindqvist, Maartje C Brink, Nico P Dantuma, Yuki Katou, Katsuhiko Shirahige, Camilla Sjögren
Publikováno v:
PLoS Genetics, Vol 10, Iss 10, p e1004680 (2014)
The cohesin complex, which is essential for sister chromatid cohesion and chromosome segregation, also inhibits resolution of sister chromatid intertwinings (SCIs) by the topoisomerase Top2. The cohesin-related Smc5/6 complex (Smc5/6) instead accumul
Externí odkaz:
https://doaj.org/article/6d6b6b3ed64b4e3f858e274984a86849
Autor:
Daniël Splinter, Marvin E Tanenbaum, Arne Lindqvist, Dick Jaarsma, Annette Flotho, Ka Lou Yu, Ilya Grigoriev, Dieuwke Engelsma, Elize D Haasdijk, Nanda Keijzer, Jeroen Demmers, Maarten Fornerod, Frauke Melchior, Casper C Hoogenraad, René H Medema, Anna Akhmanova
Publikováno v:
PLoS Biology, Vol 8, Iss 4, p e1000350 (2010)
BICD2 is one of the two mammalian homologues of the Drosophila Bicaudal D, an evolutionarily conserved adaptor between microtubule motors and their cargo that was previously shown to link vesicles and mRNP complexes to the dynein motor. Here, we iden
Externí odkaz:
https://doaj.org/article/10400eedc65345748f1c28fcffc7b328
Publikováno v:
PLoS Biology, Vol 5, Iss 5, p e123 (2007)
Activation of cyclin B1-cyclin-dependent kinase 1 (Cdk1), triggered by a positive feedback loop at the end of G2, is the key event that initiates mitotic entry. In metaphase, anaphase-promoting complex/cyclosome-dependent destruction of cyclin B1 ina
Externí odkaz:
https://doaj.org/article/feffe305d0a946218115ba6a77e14554
Autor:
Xing-Yu Li, Qiu-Gang Zong, Jian-Jun Liu, Ze-Fan Yin, Ze-Jun Hu, Xu-Zhi Zhou, Chao Yue, Zhi-Yang Liu, Xing-Xin Zhao, Zi-Kang Xie, J. Bernard Blake, Christopher T. Russell, Robert E. Ergun, Per-Arne Lindqvist
Publikováno v:
Universe, Vol 9, Iss 6, p 258 (2023)
Pulsating auroras are usually observed with ultralow-frequency (ULF) waves in the Pc 3–5 band (period 10–600 s). These auroras are thought to result from interactions between energetic electrons and chorus waves, but their relationship with ULF w
Externí odkaz:
https://doaj.org/article/b43b029ea13e41d6b52db01afc22087c
Autor:
Marko J. Kallio, Antti Poso, Lila Kallio, Arne Lindqvist, Pasi Halonen, Elvira Hukasova, Pekka Tiikkainen, Elli Narvi, Jonathan Rehnberg, Leena J. Laine, Jenni H.E. Mäki-Jouppila
Supplemental Movie 1. Cent-1 treated HeLa H2B-GFP mCherry-tubulin cells arrest in mitosis for several hours with misaligned chromosomes, followed by cell death or abnormal exit from M phase. The cell on the left hand side forms a multipolar spindle a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::048e2331a542dfa6a6340a8df14f34ef
https://doi.org/10.1158/1535-7163.22500160
https://doi.org/10.1158/1535-7163.22500160
Autor:
Marko J. Kallio, Antti Poso, Lila Kallio, Arne Lindqvist, Pasi Halonen, Elvira Hukasova, Pekka Tiikkainen, Elli Narvi, Jonathan Rehnberg, Leena J. Laine, Jenni H.E. Mäki-Jouppila
Mitosis is an attractive target for the development of new anticancer drugs. In a search for novel mitotic inhibitors, we virtually screened for low molecular weight compounds that would possess similar steric and electrostatic features, but differen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01e66c27df748880b1259d18eaba3507
https://doi.org/10.1158/1535-7163.c.6536371.v1
https://doi.org/10.1158/1535-7163.c.6536371.v1