Zobrazeno 1 - 10 of 14 pro vyhledávání: '"Arne Engelsberg"'
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Akademický článek
Efficacy and safety of avelumab treatment in patients with metastatic Merkel cell carcinoma: experience from a global expanded access program
Autor: Celeste Lebbe, Paolo Antonio Ascierto, Shahneen Sandhu, Vijay Kasturi, Luc Dirix, Paul Nathan, Subramanian Hariharan, Giovanni Grignani, Eyal Fenig, Rodrigo Munhoz, Elena Benincasa, Sarah Flaskett, Josh Reed, Arne Engelsberg
Publikováno v: Journal for ImmunoTherapy of Cancer, Vol 8, Iss 1 (2020)
Background Avelumab, a human anti–programmed death-ligand 1 immunoglobulin G1 monoclonal antibody, showed favorable efficacy and safety in patients with metastatic Merkel cell carcinoma (mMCC) in the phase II JAVELIN Merkel 200 trial, leading to ap
Externí odkaz: https://doaj.org/article/770398a7fc92446485a6070e09f8f31a
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2
Efficacy and safety of avelumab treatment in patients with metastatic Merkel cell carcinoma : experience from a global expanded access program
Autor: Vijay Kasturi, Josh Reed, Sarah Flaskett, Elena Benincasa, Paolo A. Ascierto, Giovanni Grignani, Céleste Lebbé, Arne Engelsberg, Paul Nathan, John Walker, Rodrigo Ramella Munhoz, Subramanian Hariharan, Shahneen Sandhu, Eyal Fenig, Luc Dirix
Publikováno v: Journal for immunotherapy of cancer
Journal for ImmunoTherapy of Cancer, Vol 8, Iss 1 (2020)
Journal for Immunotherapy of Cancer
BackgroundAvelumab, a human anti–programmed death-ligand 1 immunoglobulin G1 monoclonal antibody, showed favorable efficacy and safety in patients with metastatic Merkel cell carcinoma (mMCC) in the phase II JAVELIN Merkel 200 trial, leading to app
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e04fa5cc67657a7f10de54a742d8d947
https://repository.uantwerpen.be/docstore/d:irua:3784
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4
Management of crizotinib therapy for ALK-rearranged non-small cell lung carcinoma
Autor: Peter Meldgaard, Nicola Steele, Federico Cappuzzo, Patrick Schnell, Paul Germonpre, Oliver Gautschi, Ekaterini Boleti, J. Fox, Arne Engelsberg, Harry J.M. Groen, Enriqueta Felip, Juergen Wolf, Denis Moro-Sibilot, Edurne Arriola
Publikováno v: Cappuzzo, F, Moro-Sibilot, D, Gautschi, O, Boleti, E, Felip, E, Groen, H J M, Germonpré, P, Meldgaard, P, Arriola, E, Steele, N, Fox, J, Schnell, P, Engelsberg, A & Wolf, J 2015, ' Management of crizotinib therapy for ALK-rearranged non-small cell lung carcinoma: An expert consensus ', Lung Cancer, vol. 87, no. 2, pp. 89-95 . https://doi.org/10.1016/j.lungcan.2014.12.010
Within 4 years of the discovery of anaplastic lymphoma kinase (ALK) rearrangements in non-small cell lung cancer (NSCLC), the ALK inhibitor crizotinib gained US and European approval for the treatment of advanced ALK-positive NSCLC. This was due to t
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20b36e5da0ab48a187882c18681c4fbb
https://doi.org/10.1016/j.lungcan.2014.12.010
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6
Different Motifs Regulate Trafficking of SorCS1 Isoforms
Autor: Morten Nielsen, Irm Hermans-Borgmeyer, Claus Munck Petersen, Camilla Gustafsen, Peder Madsen, Arne Engelsberg, Jørgen Gliemann, Guido Hermey, Jakob J. Gutzmann, Anders Nykjaer, Karen M. Pedersen, Jida W. Hamati, Dietmar Kuhl, Sady J. Keat
Publikováno v: Nielsen, M S, Keat, S J, Hamati, J W, Madsen, P, Gutzmann, J J, Engelsberg, A, Pedersen, K-M, Gustafsen, C, Nykjaer, A, Gliemann, J, Hermans-Borgmeyer, I, Kuhl, D, Petersen, C M & Hermey, G 2008, ' Different motifs regulate trafficking of SorCS1 isoforms ', Traffic, vol. 9, no. 6, pp. 980-94 . https://doi.org/10.1111/j.1600-0854.2008.00731.x
The type I transmembrane protein SorCS1 is a member of the Vps10p-domain receptor family comprised of Sortilin, SorLA and SorCS1, -2 and -3. Current information indicates that Sortilin and SorLA mediate intracellular protein trafficking and sorting,
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d45e3a965984f99fbc4525f43ef00d9
https://doi.org/10.1111/j.1600-0854.2008.00731.x
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7
The N-terminus of the serum- and glucocorticoid-inducible kinase Sgk1 specifies mitochondrial localization and rapid turnover
Autor: Arne Engelsberg, Franziska Kobelt, Dietmar Kuhl
Publikováno v: Biochemical Journal. 399:69-76
The serine/threonine protein kinase Sgk1 (serum- and glucocorticoid-inducible kinase 1) is characterized by a short half-life and has been implicated in the control of a large variety of functions in different subcellular compartments and tissues. He
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49ac962980fc7962eff310aaf8e8ba38
https://doi.org/10.1042/bj20060386
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EBAG9 adds a new layer of control on large dense-core vesicle exocytosis via interaction with Snapin
Autor: Tatiana A Reimer, Armin Rehm, Ignacio Delgado-Martinez, Constantin Rüder, Ralf B. Nehring, Ricardo Hermosilla, Arne Engelsberg, Bernd Dörken
Publikováno v: Molecular biology of the cell. 16(3)
Regulated exocytosis is subject to several modulatory steps that include phosphorylation events and transient protein–protein interactions. The estrogen receptor-binding fragment-associated gene9 (EBAG9) gene product was recently identified as a mo
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::118e4ede3b0774f6f679deddd00bbdcd
https://pubmed.ncbi.nlm.nih.gov/15635093
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