High-throughput identification of potential minor histocompatibility antigens by MHC tetramer-based screening: feasibility and limitations.

Autor: Pleun Hombrink, Sine R Hadrup, Arne Bakker, Michel G D Kester, J H Frederik Falkenburg, Peter A von dem Borne, Ton N M Schumacher, Mirjam H M Heemskerk

Publikováno v: PLoS ONE, Vol 6, Iss 8, p e22523 (2011)

T-cell recognition of minor histocompatibility antigens (MiHA) plays an important role in the graft-versus-tumor (GVT) effect of allogeneic stem cell transplantation (allo-SCT). However, the number of MiHA identified to date remains limited, making c

Externí odkaz: https://doaj.org/article/f01a8f9b9cc748ee88f8c80cb2c7d3b9

Adeno-associated viral vector-mediated gene transfer of brain-derived neurotrophic factor reverses atrophy of rubrospinal neurons following both acute and chronic spinal cord injury

Autor: Chris W. Pool, Joost Verhaagen, Wim T. J. M. C. Hermens, Paul A. Dijkhuizen, Gerard J. Boer, Joop J. van Heerikhuize, Arne Bakker, Marc J. Ruitenberg, Erik T te Beek, Bas Blits

Publikováno v: Neurobiology of Disease, Vol 15, Iss 2, Pp 394-406 (2004)
Neurobiology of Disease, 15(2), 394-406. Academic Press

Rubrospinal neurons (RSNs) undergo marked atrophy after cervical axotomy. This progressive atrophy may impair the regenerative capacity of RSNs in response to repair strategies that are targeted to promote rubrospinal tract regeneration. Here, we inv

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::820c63b5c139dcb98db092221405c9a1
https://doi.org/10.1016/j.nbd.2003.11.018

Comprehensive analysis of the candidate genes CCL2, CCR2, and TLR4 in age-related macular degeneration

Autor: Caroline C W Klaver, Irene Barbazetto, Simone van Soest, Rando Allikmets, Paulus T. V. M. de Jong, Jana Zernant, Joanna E. Merriam, Dominiek D. G. Despriet, Arthur A.B. Bergen, R. Theodore Smith, Gaetano R. Barile, Arne Bakker

Publikováno v: Investigative ophthalmology & visual science, 49(1), 364-371. Association for Research in Vision and Ophthalmology Inc.
Investigative Ophthalmology & Visual Science, 49(1), 364-371. Association for Research in Vision and Ophthalmology Inc.
Investigative Ophthalmology & Visual Science, 49, 364-371. Association for Research in Vision and Ophthalmology Inc.

Accumulating evidence demonstrates that disregulation of the local inflammatory and immunologic response is an important causal pathway in age-related macular degeneration. Initial proof of this insight was provided by histopathology studies that sho

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a02e95740608a85552bd1192b95d9c66
https://pubmed.ncbi.nlm.nih.gov/18172114

The role of ERAAP polymorphisms in the autoimmune disease Ankylosing Spondylitis (100.17)

Autor: Arne Bakker, Nilabh Shastri

Publikováno v: The Journal of Immunology. 186:100.17-100.17

Ankylosing spondylitis (AS) is a chronic inflammatory joint disease of the axial skeleton, ultimately leading to fusion of the spine. For over three decades it has been known that the MHC class I molecule HLA-B27 is strongly associated with AS. In ad

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::dce54bfe1822de53a857dfec6e616690
https://doi.org/10.4049/jimmunol.186.supp.100.17