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Concentrating all helper protein functions on a single entity allows rescue of recombinant measles virus by transfection of just two plasmids

Autor: Arne Auste, Michael D. Mühlebach

Publikováno v: Journal of General Virology. 103

The generation of recombinant measles virus (MeV) from manipulated genomes on plasmid DNA is quite a complex and inefficient process. As a member of the order Mononegavirales its single-stranded ssRNA genome in negative sense orientation is not infec

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::596d61c6822ae20e4c19d6d1aed172af
https://doi.org/10.1099/jgv.0.001815

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Vaccine-associated enhanced respiratory pathology in COVID-19 hamsters after T(H)2-biased immunization

Vaccine-associated enhanced respiratory disease (VAERD) is a severe complication for some respiratory infections. To investigate the potential for VAERD induction in coronavirus disease 2019 (COVID-19), we evaluate two vaccine leads utilizing a sever

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27466db8ae8b4532e40612e5d44b512d
http://edoc.mdc-berlin.de/22013/7/22013suppl.zip

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Vaccine-associated enhanced respiratory pathology in COVID-19 hamsters after T

Publikováno v: Cell reports. 40(7)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::0d7e364410a511deb8eecbe2e71a7642
https://pubmed.ncbi.nlm.nih.gov/35952673

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In contrast to TH2-biased approaches, TH1 COVID-19 vaccines protect Syrian hamsters from severe disease in the absence of dexamethasone-treatable vaccine-associated enhanced respiratory pathology

Since December 2019, the novel human coronavirus SARS-CoV-2 has spread globally, causing millions of deaths. Unprecedented efforts have enabled development and authorization of a range of vaccines, which reduce transmission rates and confer protectio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c0ee66773573f04284c10a648f85bc97
https://doi.org/10.1101/2021.12.28.474359

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The green tea catechin epigallocatechin gallate inhibits SARS-CoV-2 infection

Autor: Barbara S. Schnierle, Christin Schmidt, Christine von Rhein, Christoph Schürmann, Arne Auste, Lisa Henss, Michael D. Mühlebach

Publikováno v: Journal of general virology, 102(4):001574
The Journal of General Virology

The severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection has caused a pandemic with tens of millions of cases and more than a million deaths. The infection causes COVID-19, a disease of the respiratory system of divergent severity.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb035ab00c60e306e3c0cf546b7ffa5e
https://repository.publisso.de/resource/frl:6431889

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A Highly Immunogenic Measles Virus-based Th1-biased COVID-19 Vaccine

Autor: Aileen Ebenig, Barbara S. Schnierle, Arne Auste, Maike Herrmann, Cindy Hoerner, Samada Muraleedharan, Michael D. Muehlebach, Christoph Schuermann

The COVID-19 pandemic is caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) and has spread world-wide with millions of cases and hundreds of thousands of deaths to date. The gravity of the situation mandates accelerated efforts to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::071371919afee4fb2d15c757d6530d5a
https://doi.org/10.1101/2020.07.11.198291

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