Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Arne, Alder"'
Autor:
Benjamin Liffner, Juan Miguel Balbin, Gerald J. Shami, Ghizal Siddiqui, Jan Strauss, Sonja Frölich, Gary K. Heinemann, Ella May Edwards, Arne Alder, Jan Stephan Wichers, Darren J. Creek, Leann Tilley, Matthew W. A. Dixon, Tim-Wolf Gilberger, Danny W. Wilson
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-17 (2022)
Benjamin Liffner and Miguel Balbin et al. report that the Plasmodium falciparum protein, PfCERLI2, localises to the cytosolic face of the parasite’s rhoptry bulb and is essential for invasion and growth within human red blood cells.
Externí odkaz:
https://doaj.org/article/70f7a6eab0ab4db184482b483285f76e
Autor:
Sylwia D. Boltryk, Armin Passecker, Arne Alder, Eilidh Carrington, Marga van de Vegte-Bolmer, Geert-Jan van Gemert, Alex van der Starre, Hans-Peter Beck, Robert W. Sauerwein, Taco W. A. Kooij, Nicolas M. B. Brancucci, Nicholas I. Proellochs, Tim-Wolf Gilberger, Till S. Voss
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
During each replication cycle of P. falciparum in the human bloodstream, a small proportion of parasites commits to sexual development and differentiates into transmission-relevant gametocytes. Applying CRISPR-based genome editing, Boltryk et al. eng
Externí odkaz:
https://doaj.org/article/bdde91798fe34a80b40c88b2bfa92cdd
Autor:
Jan Stephan Wichers, Paolo Mesén-Ramírez, Gwendolin Fuchs, Jing Yu-Strzelczyk, Jan Stäcker, Heidrun von Thien, Arne Alder, Isabelle Henshall, Benjamin Liffner, Georg Nagel, Christian Löw, Danny Wilson, Tobias Spielmann, Shiqiang Gao, Tim-Wolf Gilberger, Anna Bachmann, Jan Strauss
Publikováno v:
mBio, Vol 13, Iss 2 (2022)
ABSTRACT Membrane transport proteins perform crucial roles in cell physiology. The obligate intracellular parasite Plasmodium falciparum, an agent of human malaria, relies on membrane transport proteins for the uptake of nutrients from the host, disp
Externí odkaz:
https://doaj.org/article/a379ad10a39b42889f322ee25fa90b4b
Autor:
Andreas Masch, Abed Nasereddin, Arne Alder, Megan J. Bird, Sandra I. Schweda, Lutz Preu, Christian Doerig, Ron Dzikowski, Tim W. Gilberger, Conrad Kunick
Publikováno v:
Malaria Journal, Vol 18, Iss 1, Pp 1-10 (2019)
Abstract Background Malaria is one of the most prevalent tropical infectious diseases. Since recently cases of artemisinin resistance were reported, novel anti-malarial drugs are required which differ from artemisinins in structure and biological tar
Externí odkaz:
https://doaj.org/article/86bec5b15da04074875dc25fedb8b09d
Autor:
Duc Hoàng Lande, Abed Nasereddin, Arne Alder, Tim W. Gilberger, Ron Dzikowski, Johann Grünefeld, Conrad Kunick
Publikováno v:
Molecules, Vol 26, Iss 16, p 4739 (2021)
Malaria is one of the most dangerous infectious diseases. Because the causative Plasmodium parasites have developed resistances against virtually all established antimalarial drugs, novel antiplasmodial agents are required. In order to target plasmod
Externí odkaz:
https://doaj.org/article/5df4c79b354a40a084493015f536cf70
Publikováno v:
Molecules, Vol 25, Iss 14, p 3187 (2020)
Malaria causes hundreds of thousands of deaths every year, making it one of the most dangerous infectious diseases worldwide. Because the pathogens have developed resistance against most of the established anti-malarial drugs, new antiplasmodial agen
Externí odkaz:
https://doaj.org/article/db89399e15d342368dca7d1e3ceb4e37
Autor:
Janna Ehlert, Arne Alder, Viola Introini, Julia Weder, Pietro Cicuta, Tim W. Gilberger, Matthias Preller
Publikováno v:
Proceedings, Vol 22, Iss 1, p 9 (2019)
Malaria remains a devastating disease with nearly half a million deaths per year. The WHO reports a stagnating number of new infections every year without a significant decline, as a result of insufficient access to antimalarials in endemic regions a
Externí odkaz:
https://doaj.org/article/ed33126c845d49a7a3316f80cb189213
Autor:
Jan Stephan, Wichers, Paolo, Mesén-Ramírez, Gwendolin, Fuchs, Jing, Yu-Strzelczyk, Jan, Stäcker, Heidrun, von Thien, Arne, Alder, Isabelle, Henshall, Benjamin, Liffner, Georg, Nagel, Christian, Löw, Danny, Wilson, Tobias, Spielmann, Shiqiang, Gao, Tim-Wolf, Gilberger, Anna, Bachmann, Jan, Strauss
Publikováno v:
mBio. 13(2)
Membrane transport proteins perform crucial roles in cell physiology. The obligate intracellular parasite Plasmodium falciparum, an agent of human malaria, relies on membrane transport proteins for the uptake of nutrients from the host, disposal of m
Autor:
Arne Alder, Louisa Wilcke, Emma Pietsch, Heidrun von Thien, Samuel Pazicky, Christian Löw, Paolo Mesen-Ramirez, Anna Bachmann, Paul-Christian Burda, Conrad Kunick, Holger Sondermann, Danny Wilson, Tim-Wolf Gilberger
Publikováno v:
The journal of biological chemistry 298(9), 102360 (2022). doi:10.1016/j.jbc.2022.102360
JBC 298(9), 102360 (2022). doi:10.1016/j.jbc.2022.102360
Malaria is responsible for hundreds of thousands of deaths every year. The lack of an effective vaccine and the global spread of multidrug resistant parasites hampers the fight against the
Malaria is responsible for hundreds of thousands of deaths every year. The lack of an effective vaccine and the global spread of multidrug resistant parasites hampers the fight against the
Autor:
Arne Alder, Tim W. Gilberger, Conrad Kunick, Duc Hoàng Lande, Abed Nasereddin, Johann Grünefeld, Ron Dzikowski
Publikováno v:
Molecules
Molecules 26 (2021) 4739. https://doi.org/10.3390/molecules26164739--Molecules : CD-ROM Edition ; an advanced forum for innovative research in organic, bio-organic, and medicinical chemistry--1420-3049--1420-3049
Molecules, Vol 26, Iss 4739, p 4739 (2021)
Volume 26
Issue 16
Molecules 26 (2021) 4739. https://doi.org/10.3390/molecules26164739--Molecules : CD-ROM Edition ; an advanced forum for innovative research in organic, bio-organic, and medicinical chemistry--1420-3049--1420-3049
Molecules, Vol 26, Iss 4739, p 4739 (2021)
Volume 26
Issue 16
Malaria is one of the most dangerous infectious diseases. Because the causative Plasmodium parasites have developed resistances against virtually all established antimalarial drugs, novel antiplasmodial agents are required. In order to target plasmod