Non-invasive surrogate markers of pulmonary hypertension are associated with poor survival in patients with cancer.

Autor: Cekay M; Institute for Lung Health (ILH), Justus-Liebig-University Giessen, Giessen, Germany.; Department of Internal Medicine, Justus-Liebig-University Giessen, Universities of Giessen and Marburg Lung Center (UGMLC), Member of the German Center for Lung Research (DZL), Giessen, Germany., Arndt PF; Institute for Lung Health (ILH), Justus-Liebig-University Giessen, Giessen, Germany.; Department of Internal Medicine, Justus-Liebig-University Giessen, Universities of Giessen and Marburg Lung Center (UGMLC), Member of the German Center for Lung Research (DZL), Giessen, Germany., Franken JK; Department of Internal Medicine, Justus-Liebig-University Giessen, Universities of Giessen and Marburg Lung Center (UGMLC), Member of the German Center for Lung Research (DZL), Giessen, Germany., Wilhelm J; Institute for Lung Health (ILH), Justus-Liebig-University Giessen, Giessen, Germany.; Department of Internal Medicine, Justus-Liebig-University Giessen, Universities of Giessen and Marburg Lung Center (UGMLC), Member of the German Center for Lung Research (DZL), Giessen, Germany., Pullamsetti SS; Institute for Lung Health (ILH), Justus-Liebig-University Giessen, Giessen, Germany.; Department of Internal Medicine, Justus-Liebig-University Giessen, Universities of Giessen and Marburg Lung Center (UGMLC), Member of the German Center for Lung Research (DZL), Giessen, Germany.; Max Planck Institute for Heart and Lung Research, Member of the DZL, Member of CPI, Bad Nauheim, Germany., Roller FC; Department of Radiology, Justus-Liebig-University Giessen, Universities of Giessen and Marburg Lung Center (UGMLC), Giessen, Germany., Sommer N; Institute for Lung Health (ILH), Justus-Liebig-University Giessen, Giessen, Germany.; Department of Internal Medicine, Justus-Liebig-University Giessen, Universities of Giessen and Marburg Lung Center (UGMLC), Member of the German Center for Lung Research (DZL), Giessen, Germany., Askevold I; Department of General Surgery, Justus-Liebig-University Giessen, Giessen, Germany., Lüdecke G; Department of Urology, Justus-Liebig-University Giessen, Giessen, Germany., Langer C; Department of Otorhinolaryngology, Justus-Liebig-University Giessen, Giessen, Germany., Stein M; Department of Neurosurgery, Justus-Liebig-University Giessen, Giessen, Germany., Zeppernick F; Institute of Gynecology and Obstetrics, Faculty of Medicine, Justus-Liebig-University Giessen, Giessen, Germany., Tello K; Institute for Lung Health (ILH), Justus-Liebig-University Giessen, Giessen, Germany.; Department of Internal Medicine, Justus-Liebig-University Giessen, Universities of Giessen and Marburg Lung Center (UGMLC), Member of the German Center for Lung Research (DZL), Giessen, Germany., Sibelius U; Department of Internal Medicine, Justus-Liebig-University Giessen, Universities of Giessen and Marburg Lung Center (UGMLC), Member of the German Center for Lung Research (DZL), Giessen, Germany., Grimminger F; Institute for Lung Health (ILH), Justus-Liebig-University Giessen, Giessen, Germany.; Department of Internal Medicine, Justus-Liebig-University Giessen, Universities of Giessen and Marburg Lung Center (UGMLC), Member of the German Center for Lung Research (DZL), Giessen, Germany., Seeger W; Institute for Lung Health (ILH), Justus-Liebig-University Giessen, Giessen, Germany.; Department of Internal Medicine, Justus-Liebig-University Giessen, Universities of Giessen and Marburg Lung Center (UGMLC), Member of the German Center for Lung Research (DZL), Giessen, Germany.; Max Planck Institute for Heart and Lung Research, Member of the DZL, Member of CPI, Bad Nauheim, Germany., Savai R; Institute for Lung Health (ILH), Justus-Liebig-University Giessen, Giessen, Germany rajkumar.savai@mpi-bn.mpg.de.; Department of Internal Medicine, Justus-Liebig-University Giessen, Universities of Giessen and Marburg Lung Center (UGMLC), Member of the German Center for Lung Research (DZL), Giessen, Germany.; Max Planck Institute for Heart and Lung Research, Member of the DZL, Member of CPI, Bad Nauheim, Germany., Eul B; Department of Internal Medicine, Justus-Liebig-University Giessen, Universities of Giessen and Marburg Lung Center (UGMLC), Member of the German Center for Lung Research (DZL), Giessen, Germany.

Publikováno v: BMJ open respiratory research [BMJ Open Respir Res] 2024 Aug 22; Vol. 11 (1). Date of Electronic Publication: 2024 Aug 22.

Modeling the mosaic structure of bacterial genomes to infer their evolutionary history.

Autor: Sheinman M; Institute for Advanced Studies, Sevastopol State University, Sevastopol 299053, Crimea., Arndt PF; Department of Computational Molecular Biology, Max Planck Institute for Molecular Genetics, Berlin 12163, Germany., Massip F; Department U900, Centre for Computational Biology, Mines Paris, PSL University, Paris 75006, France.; Department U900, Institut Curie, Université Paris Sciences et Lettres, Paris 75005, France.; INSERM, U900, Paris 75005, France.

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2024 Mar 26; Vol. 121 (13), pp. e2313367121. Date of Electronic Publication: 2024 Mar 22.

Case Report: Durable therapy response to Osimertinib in rare EGFR Exon 18 mutated NSCLC.

Autor: Cekay M; Department of Internal Medicine, Justus-Liebig-University Giessen, Universities of Giessen and Marburg Lung Center (UGMLC), Member of the German Center for Lung Research (DZL), Giessen, Germany., Arndt PF; Department of Internal Medicine, Justus-Liebig-University Giessen, Universities of Giessen and Marburg Lung Center (UGMLC), Member of the German Center for Lung Research (DZL), Giessen, Germany.; Max Planck Institute for Heart and Lung Research, Member of the DZL, Member of CPI, Giessen, Germany., Dumitrascu R; Department of Internal Medicine, Justus-Liebig-University Giessen, Universities of Giessen and Marburg Lung Center (UGMLC), Member of the German Center for Lung Research (DZL), Giessen, Germany., Savai R; Department of Internal Medicine, Justus-Liebig-University Giessen, Universities of Giessen and Marburg Lung Center (UGMLC), Member of the German Center for Lung Research (DZL), Giessen, Germany.; Max Planck Institute for Heart and Lung Research, Member of the DZL, Member of CPI, Giessen, Germany.; Institute for Lung Health (ILH), Justus Liebig University, Giessen, Germany.; Frankfurt Cancer Institute (FCI), Goethe University, Frankfurt, Germany., Braeuninger A; Department of Pathology, Justus-Liebig-University Giessen, Universities of Giessen and Marburg Lung Center (UGMLC), Giessen, Germany., Gattenloehner S; Department of Pathology, Justus-Liebig-University Giessen, Universities of Giessen and Marburg Lung Center (UGMLC), Giessen, Germany., Steiner D; Department of Nuclear Medicine, Justus-Liebig-University Giessen, Universities of Giessen and Marburg Lung Center (UGMLC), Giessen, Germany., Roller F; Department of Radiology, Justus-Liebig-University Giessen, Universities of Giessen and Marburg Lung Center (UGMLC), Giessen, Germany., Tello K; Department of Internal Medicine, Justus-Liebig-University Giessen, Universities of Giessen and Marburg Lung Center (UGMLC), Member of the German Center for Lung Research (DZL), Giessen, Germany., Hattar K; Department of Internal Medicine, Justus-Liebig-University Giessen, Universities of Giessen and Marburg Lung Center (UGMLC), Member of the German Center for Lung Research (DZL), Giessen, Germany., Seeger W; Department of Internal Medicine, Justus-Liebig-University Giessen, Universities of Giessen and Marburg Lung Center (UGMLC), Member of the German Center for Lung Research (DZL), Giessen, Germany., Sibelius U; Department of Internal Medicine, Justus-Liebig-University Giessen, Universities of Giessen and Marburg Lung Center (UGMLC), Member of the German Center for Lung Research (DZL), Giessen, Germany., Grimminger F; Department of Internal Medicine, Justus-Liebig-University Giessen, Universities of Giessen and Marburg Lung Center (UGMLC), Member of the German Center for Lung Research (DZL), Giessen, Germany., Eul B; Department of Internal Medicine, Justus-Liebig-University Giessen, Universities of Giessen and Marburg Lung Center (UGMLC), Member of the German Center for Lung Research (DZL), Giessen, Germany.

Publikováno v: Frontiers in oncology [Front Oncol] 2023 Aug 16; Vol. 13, pp. 1182391. Date of Electronic Publication: 2023 Aug 16 (Print Publication: 2023).

Enhanced cortical neural stem cell identity through short SMAD and WNT inhibition in human cerebral organoids facilitates emergence of outer radial glial cells.

Autor: Rosebrock D; Department of Genome Regulation, Max Planck Institute for Molecular Genetics, Berlin, Germany.; Department of Computational Biology, Max Planck Institute for Molecular Genetics, Berlin, Germany.; Department of Mathematics and Computer Science, Freie Universität Berlin, Berlin, Germany., Arora S; Department of Genome Regulation, Max Planck Institute for Molecular Genetics, Berlin, Germany.; Department of Cell and Developmental Biology, Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel.; Institute of Biology, Department of Biology, Chemistry, and Pharmacy, Freie Universität Berlin, Berlin, Germany., Mutukula N; Department of Genome Regulation, Max Planck Institute for Molecular Genetics, Berlin, Germany.; Department of Cell and Developmental Biology, Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel.; Institute of Chemistry and Biochemistry, Department of Biology, Chemistry and Pharmacy, Freie Universität Berlin, Berlin, Germany., Volkman R; Department of Cell and Developmental Biology, Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel., Gralinska E; Department of Computational Biology, Max Planck Institute for Molecular Genetics, Berlin, Germany.; Department of Mathematics and Computer Science, Freie Universität Berlin, Berlin, Germany., Balaskas A; Department of Genome Regulation, Max Planck Institute for Molecular Genetics, Berlin, Germany.; Institute of Chemistry and Biochemistry, Department of Biology, Chemistry and Pharmacy, Freie Universität Berlin, Berlin, Germany., Aragonés Hernández A; Department of Genome Regulation, Max Planck Institute for Molecular Genetics, Berlin, Germany.; Institute of Biology, Department of Biology, Chemistry, and Pharmacy, Freie Universität Berlin, Berlin, Germany., Buschow R; Microscopy and Cryo-Electron Microscopy, Max Planck Institute for Molecular Genetics, Berlin, Germany., Brändl B; Department of Genome Regulation, Max Planck Institute for Molecular Genetics, Berlin, Germany.; Department of Psychiatry and Psychotherapy, University Hospital Schleswig Holstein, Kiel, Germany., Müller FJ; Department of Genome Regulation, Max Planck Institute for Molecular Genetics, Berlin, Germany.; Department of Psychiatry and Psychotherapy, University Hospital Schleswig Holstein, Kiel, Germany., Arndt PF; Department of Computational Biology, Max Planck Institute for Molecular Genetics, Berlin, Germany., Vingron M; Department of Computational Biology, Max Planck Institute for Molecular Genetics, Berlin, Germany., Elkabetz Y; Department of Genome Regulation, Max Planck Institute for Molecular Genetics, Berlin, Germany. elkabetz@molgen.mpg.de.; Department of Cell and Developmental Biology, Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel. elkabetz@molgen.mpg.de.

Publikováno v: Nature cell biology [Nat Cell Biol] 2022 Jun; Vol. 24 (6), pp. 981-995. Date of Electronic Publication: 2022 Jun 13.

Identical sequences found in distant genomes reveal frequent horizontal transfer across the bacterial domain.

Autor: Sheinman M; Theoretical Biology and Bioinformatics, Biology Department, Utrecht University, Utrecht, Netherlands.; Division of Molecular Carcinogenesis, the Netherlands Cancer Institute, Amsterdam, Netherlands., Arkhipova K; Theoretical Biology and Bioinformatics, Biology Department, Utrecht University, Utrecht, Netherlands., Arndt PF; Max Planck Institute for Molecular Genetics, Berlin, Germany., Dutilh BE; Theoretical Biology and Bioinformatics, Biology Department, Utrecht University, Utrecht, Netherlands., Hermsen R; Theoretical Biology and Bioinformatics, Biology Department, Utrecht University, Utrecht, Netherlands., Massip F; Berlin Institute for Medical Systems Biology, Max Delbrück Center, Berlin, Germany.; Université de Lyon, Université Lyon 1, CNRS, Laboratoire de Biométrie et Biologie Evolutive UMR 5558, Villleurbanne, France.

Publikováno v: ELife [Elife] 2021 Jun 14; Vol. 10. Date of Electronic Publication: 2021 Jun 14.