Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Arndt F Siekmann"'
Autor:
Ricardo J Figueroa, Gonzalo Carrasco-Avino, Ignacio A Wichmann, Martin Lange, Gareth I Owen, Arndt F Siekmann, Alejandro H Corvalán, Juan C Opazo, Julio D Amigo
Publikováno v:
PLoS ONE, Vol 12, Iss 5, p e0178274 (2017)
Reprimo (RPRM), a member of the RPRM gene family, is a tumor-suppressor gene involved in the regulation of the p53-mediated cell cycle arrest at G2/M. RPRM has been associated with malignant tumor progression and proposed as a potential biomarker for
Externí odkaz:
https://doaj.org/article/9cbee38730524667b02d8d6c0c3629a2
Publikováno v:
PLoS ONE, Vol 12, Iss 8, p e0183433 (2017)
The aryl hydrocarbon receptor (AHR) is a basic helix-loop-helix transcription factor conserved across phyla from flies to humans. Activated by a number of endogenous ligands and environmental toxins, studies on AHR function and gene regulation have l
Externí odkaz:
https://doaj.org/article/3788cefa988c4630bdaf91b71b7a7a5f
Autor:
Eva Kochhan, Anna Lenard, Elin Ellertsdottir, Lukas Herwig, Markus Affolter, Heinz-Georg Belting, Arndt F Siekmann
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e75060 (2013)
After the initial formation of a highly branched vascular plexus, blood vessel pruning generates a hierarchically structured network with improved flow characteristics. We report here on the cellular events that occur during the pruning of a defined
Externí odkaz:
https://doaj.org/article/eefb8d47bd6741a380598da98870d47f
Publikováno v:
Development. 150
Blood vessels form elaborate networks that depend on tissue-specific signalling pathways and anatomical structures to guide their growth. However, it is not clear which morphogenetic principles organize the stepwise assembly of the vasculature. We th
Blood vessels form elaborate networks depending on tissue-specific signalling pathways and anatomical structures to guide their growth. However, it is not clear which morphogenetic principles organize the stepwise assembly of the vasculature. We thus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1ed35947548a147690c14bb84587609c
https://doi.org/10.1101/2022.06.14.496153
https://doi.org/10.1101/2022.06.14.496153
Autor:
Roman Tsaryk, Nora Yucel, Elvin V. Leonard, Noelia Diaz, Olga Bondareva, Maria Odenthal-Schnittler, Zoltan Arany, Juan M. Vaquerizas, Hans Schnittler, Arndt F. Siekmann
Publikováno v:
Sci. Rep. 12:4795 (2022)
Endothelial cells (ECs) lining blood vessels are exposed to mechanical forces, such as shear stress. These forces control many aspects of EC biology, including vascular tone, cell migration and proliferation. Despite a good understanding of the genes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5ac0d098477cfe431779e3f8ef2d6ae
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=64620
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=64620
Autor:
Nora Yucel, Juan M. Vaquerizas, Zoltan Arany, Noelia Díaz, Leonard Ev, H. Schnittler, M. Odenthal-Schnittler, Olga Bondareva, R. Tsaryk, Arndt F. Siekmann
Endothelial cells (EC) lining blood vessels are exposed to mechanical forces, such as shear stress exerted by the flowing blood. These forces control many aspects of EC biology, including vascular tone, cell migration and proliferation in addition to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e46369684db476f3222cde2209dd94fd
https://doi.org/10.1101/2021.09.21.460846
https://doi.org/10.1101/2021.09.21.460846
Autor:
Martin Lange, Nils Ohnesorge, Dennis Hoffmann, Susana F. Rocha, Rui Benedito, Arndt F. Siekmann
Publikováno v:
Developmental biology. 486
The formation of appropriately patterned blood vessel networks requires endothelial cell migration and proliferation. Signaling through the Vascular Endothelial Growth Factor A (VEGFA) pathway is instrumental in coordinating these processes. mRNA spl
Autor:
Vesna Bojovic, Hans-J. Schnittler, Olga Bondareva, Roman Tsaryk, Arndt F. Siekmann, Maria Odenthal-Schnittler
Publikováno v:
Cardiovasc Res
Aims Oscillatory shear stress (OSS) is an atheroprone haemodynamic force that occurs in areas of vessel irregularities and is implicated in the pathogenesis of atherosclerosis. Changes in signalling and transcriptional programme in response to OSS ha
Autor:
Elvin V. Leonard, Ricardo J. Figueroa, Jeroen Bussmann, Nathan D. Lawson, Julio D. Amigo, Arndt F. Siekmann
Publikováno v:
Development
Development, 149(7):dev199640
Development, 149(7):dev199640
Vascular networks comprise endothelial cells and mural cells, which include pericytes and smooth muscle cells. To elucidate the mechanisms controlling mural cell recruitment during development and tissue regeneration, we studied zebrafish caudal fin