Zobrazeno 1 - 10
of 117
pro vyhledávání: '"Arndt A. Schmitz"'
Autor:
Wei Zhang, Arndt A. Schmitz, Roosa E. Kallionpää, Merja Perälä, Niina Pitkänen, Mikko Tukiainen, Erika Alanne, Korinna Jöhrens, Renate Schulze-Rath, Bahman Farahmand, Jihong Zong
Publikováno v:
Acta Oncologica, Vol 63, Iss 1 (2024)
Background: Neurotrophic tyrosine receptor kinase (NTRK) gene fusions are oncogenic drivers. Using the Auria Biobank in Finland, we aimed to identify and characterize patients with these gene fusions, and describe their clinical and tumor characteris
Externí odkaz:
https://doaj.org/article/e095f9124f444d38a0377cda8832f56f
Autor:
John Bridgewater, Xiaolong Jiao, Mounika Parimi, Clare Flach, Jeran Stratford, Atanas Kamburov, Arndt A. Schmitz, Jihong Zong, John A. Reeves, Karen Keating, Amanda Bruno, Marc Fellous, Mariana Buongermino Pereira, Lyudmila Bazhenova
Publikováno v:
Cancer Treatment and Research Communications, Vol 33, Iss , Pp 100623- (2022)
Introduction: Neurotrophic tyrosine receptor kinase (NTRK) gene fusions are oncogenic drivers in various tumor types. Limited data exist on the overall survival (OS) of patients with tumors with NTRK gene fusions and on the co-occurrence of NTRK fusi
Externí odkaz:
https://doaj.org/article/9812c0175f7c49efba2bd73e1fd443b6
Autor:
David Vizcaya, Bahman Farahmand, Annette O. Walter, Christoph Kneip, Korinna Jöhrens, Mikko Tukiainen, Arndt A. Schmitz
Publikováno v:
Cancer Treatment and Research Communications, Vol 25, Iss , Pp 100260- (2020)
Objectives: We aimed to describe mesothelin (MSLN) and programmed cell death 1 ligand 1 (PD-L1) tumour overexpression amongst patients with malignant mesothelioma (MM), and their associations with survival, amongst a cohort of patients with MM in Fin
Externí odkaz:
https://doaj.org/article/fd3e169f9bff476293193501e828ad3d
Autor:
Wei Zhang, Merja Perälä, Roosa E. Kallionpää, Niina Pitkänen, Korinna Jöhrens, Renate Schulze-Rath, Arndt A Schmitz, Helen Guo, Jihong Zong
Publikováno v:
Cancer Research. 83:925-925
Introduction: Selective tropomyosin receptor kinase (TRK) inhibitors are targeted therapies for patients with solid tumors harboring a neurotrophic-receptor tyrosine kinase (NTRK) gene fusion. Estimates of the frequency of NTRK gene fusions and knowl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b134c3d008047c9981f012666f4593e1
https://doi.org/10.1158/1538-7445.am2023-925
https://doi.org/10.1158/1538-7445.am2023-925
Publikováno v:
Journal of Biological Chemistry. 275:20873-20879
It is widely assumed that the members of the MARCKS protein family, MARCKS (an acronym for myristoylated alanine-rich C kinase substrate) and MARCKS-related protein (MRP), interact with actin via their effector domain, a highly basic segment composed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d5694da8a68d39040dd17591d0743304
https://doi.org/10.1074/jbc.m910298199
https://doi.org/10.1074/jbc.m910298199
Publikováno v:
Proceedings of the National Academy of Sciences. 97:5191-5196
MARCKS-related protein (MRP) is a myristoylated protein kinase C substrate that binds calmodulin (CaM) with nanomolar affinity. To obtain structural information on this protein, we have engineered 10 tryptophan residues between positions 89 and 104 i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::859bf4f19956282b56db1e4e424e62b2
https://doi.org/10.1073/pnas.090500397
https://doi.org/10.1073/pnas.090500397
Autor:
Mario Roggero, Adriana Ransijn, Arndt A.P. Schmitz, Pascal Schneider, Jacques Mauël, Sally Betz Corradin, Giampietro Corradin, Guy Vergères
Publikováno v:
Journal of Biological Chemistry, vol. 274, no. 36, pp. 25411-25418
Myristoylated alanine-rich C kinase substrate (MARCKS) and MARCKS-related protein (MRP; MacMARCKS) are protein kinase C substrates in diverse cell types. Activation of murine macrophages by cytokines increases MRP expression, but infection with Leish
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18b8ff7c206b20a38a6538d4bd23a4c2
https://doi.org/10.1074/jbc.274.36.25411
https://doi.org/10.1074/jbc.274.36.25411
Autor:
Angelika Loidl-Stahlhofen, Cornelia Röhring, Arndt A.P. Schmitz, Enrico Schleiff, Guy Vergères
Publikováno v:
Analytical Biochemistry. 268:343-353
The determination of partition coefficients is crucial for the biochemical analysis of membrane-based processes, but requires tedious procedures. We have facilitated this analysis using a silica gel coated with a single phospholipid bilayer (TRANSIL)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfb418ab330c52d0ccf9f0cdd2822766
https://doi.org/10.1006/abio.1998.3080
https://doi.org/10.1006/abio.1998.3080
Autor:
Guy Vergères, Stéphane Manenti, Arndt A.P. Schmitz, R. A. Jeffrey McIlhinney, Enrico Schleiff
Publikováno v:
Journal of Biological Chemistry. 271:26794-26802
The members of the myristoylated alanine-rich C kinase substrate (MARCKS) family are proteins essential for brain development and phagocytosis. MARCKS proteins bind to actin filaments and calmodulin (CaM) and are phosphorylated by protein kinase C. I
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75ac73cc42e8c8e76d547fb3d93d5664
https://doi.org/10.1074/jbc.271.43.26794
https://doi.org/10.1074/jbc.271.43.26794
Autor:
Pereira-Figueiredo, Inês1,2 (AUTHOR) inesbarrancos@usal.es, Umeoka, Eduardo H. L.3 (AUTHOR) eduardoumeoka@gmail.com
Publikováno v:
Encyclopedia. Jun2024, Vol. 4 Issue 2, p1026-1043. 18p.