Zobrazeno 1 - 10
of 2 495
pro vyhledávání: '"Arndt Hartmann"'
Autor:
August Fiegl, Olaf Wendler, Johannes Giedl, Nadine T. Gaisa, Georg Richter, Valentina Campean, Maximilian Burger, Femke Simmer, Iris Nagtegaal, Bernd Wullich, Simone Bertz, Arndt Hartmann, Robert Stoehr
Publikováno v:
Current Oncology, Vol 31, Iss 10, Pp 5752-5761 (2024)
Penile squamous cell carcinoma (pSCC) is a rare malignancy with a global incidence ranging from 0.1 to 0.7 per 100,000 males. Prognosis is generally favorable for localized tumors, but metastatic pSCC remains challenging, with low survival rates. The
Externí odkaz:
https://doaj.org/article/14907560a88b43e28cf14c2e4cc6ef12
Autor:
Stefan Lohse, Jan Niklas Mink, Lea Eckhart, Muriel Charlotte Hans, Leuart Jusufi, Anabel Zwick, Tobias Mohr, Isabelle Ariane Bley, Oybek Khalmurzaev, Vsevolod Borisovich Matveev, Philine Loertzer, Alexey Pryalukhin, Arndt Hartmann, Carol-Immanuel Geppert, Hagen Loertzer, Heiko Wunderlich, Hans-Peter Lenhof, Carsten Maik Naumann, Holger Kalthoff, Kerstin Junker
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract PeCa is a rare entity with rising incidence rates due to increased infections with human papillomaviruses (HPV). The distinct subtypes of PeCa with an individual pathogenesis demand biomarkers for a precise patient risk assessment regarding
Externí odkaz:
https://doaj.org/article/44685576c60d4956a0b1b1ae91aa2404
Autor:
Peter A. Fasching, Chunling Hu, Steven N. Hart, Matthias Ruebner, Eric C. Polley, Rohan D. Gnanaolivu, Andreas D. Hartkopf, Hanna Huebner, Wolfgang Janni, Peyman Hadji, Hans Tesch, Sabrina Uhrig, Johannes Ettl, Michael P. Lux, Diana Lüftner, Markus Wallwiener, Lena A. Wurmthaler, Chloë Goossens, Volkmar Müller, Matthias W. Beckmann, Alexander Hein, Daniel Anetsberger, Erik Belleville, Pauline Wimberger, Michael Untch, Arif B. Ekici, Hans-Christian Kolberg, Arndt Hartmann, Florin-Andrei Taran, Tanja N. Fehm, Diethelm Wallwiener, Sara Y. Brucker, Andreas Schneeweiss, Lothar Häberle, Fergus J. Couch
Publikováno v:
npj Breast Cancer, Vol 10, Iss 1, Pp 1-7 (2024)
Abstract Germline mutations in BRCA1 and BRCA2 (gBRCA1/2) are required for a PARP inhibitor therapy in patients with HER2-negative (HER2−) advanced breast cancer (aBC). However, little is known about the prognostic impact of gBRCA1/2 mutations in a
Externí odkaz:
https://doaj.org/article/7fc65e7d8ec9445caafcbb4945b9c522
Autor:
Junnan Liu, Xue Wang, Wencheng Jiang, Anca Azoitei, Tim Eiseler, Markus Eckstein, Arndt Hartmann, Stephan Stilgenbauer, Mohamed Elati, Meike Hohwieler, Alexander Kleger, Axel John, Felix Wezel, Friedemann Zengerling, Christian Bolenz, Cagatay Günes
Publikováno v:
Cellular & Molecular Biology Letters, Vol 29, Iss 1, Pp 1-29 (2024)
Abstract Background We have previously identified an unsuspected role for GJB3 showing that the deficiency of this connexin protein induces aneuploidy in human and murine cells and accelerates cell transformation as well as tumor formation in xenogra
Externí odkaz:
https://doaj.org/article/f3dd2d1ae1494471a8095c3f91f82dd1
Autor:
Petr Kuritcyn, Rosalie Kletzander, Sophia Eisenberg, Thomas Wittenberg, Volker Bruns, Katja Evert, Felix Keil, Paul K. Ziegler, Katrin Bankov, Peter Wild, Markus Eckstein, Arndt Hartmann, Carol I. Geppert, Michaela Benz
Publikováno v:
Journal of Pathology Informatics, Vol 15, Iss , Pp 100388- (2024)
A vast multitude of tasks in histopathology could potentially benefit from the support of artificial intelligence (AI). Many examples have been shown in the literature and first commercial products with FDA or CE-IVDR clearance are available. However
Externí odkaz:
https://doaj.org/article/5c6c7078dd8a43fa8158d82137e55b90
Autor:
Lukas Heger, Gordon F. Heidkamp, Lukas Amon, Falk Nimmerjahn, Tobias Bäuerle, Andreas Maier, Ramona Erber, Arndt Hartmann, Carolin C. Hack, Matthias Ruebner, Hanna Huebner, Peter Fasching, Matthias W. Beckmann, Diana Dudziak
Publikováno v:
OncoImmunology, Vol 13, Iss 1 (2024)
Breast cancer is the most common malignancy in women worldwide and a highly heterogeneous disease. Four different subtypes are described that differ in the expression of hormone receptors as well as the growth factor receptor HER2. Treatment modaliti
Externí odkaz:
https://doaj.org/article/2fea48d7018642c3a2bf91299e025a26
Autor:
Annalena Branz, Christian Matek, Fabienne Lange, Veronika Bahlinger, Niklas Klümper, Michael Hölzel, Pamela L. Strissel, Reiner Strick, Danijel Sikic, Sven Wach, Helge Taubert, Bernd Wullich, Arndt Hartmann, Barbara Seliger, Markus Eckstein
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionUrothelial bladder cancer is frequent and exhibits diverse prognoses influenced by molecular subtypes, urothelial subtype histology, and immune microenvironments. HLA-G, known for immune regulation, displays significant membranous express
Externí odkaz:
https://doaj.org/article/9a3359d7262e4505b637932af7440aae
Autor:
Marion Dörrich, Markus Hecht, Rainer Fietkau, Arndt Hartmann, Heinrich Iro, Antoniu-Oreste Gostian, Markus Eckstein, Andreas M. Kist
Publikováno v:
Diagnostic Pathology, Vol 18, Iss 1, Pp 1-11 (2023)
Abstract Purpose Although neural networks have shown remarkable performance in medical image analysis, their translation into clinical practice remains difficult due to their lack of interpretability. An emerging field that addresses this problem is
Externí odkaz:
https://doaj.org/article/5c63d1fe106943e8a343a18f29159cb6
Autor:
Elisabeth Naschberger, Maximilian Fuchs, Nicholas Dickel, Meik Kunz, Bernt Popp, Charles Gwellem Anchang, Richard Demmler, Yanmin Lyu, Steffen Uebe, Arif Bülent Ekici, Carol Immanuel Geppert, Arndt Hartmann, Christian Flierl, Katja Petter, Tobias Gass, Simon Völkl, Michael Scharl, Andreas Ramming, Claudia Günther, Susanne Merkel, Vera Simone Schellerer, Michael Stürzl
Publikováno v:
Cancer Communications, Vol 43, Iss 11, Pp 1280-1285 (2023)
Externí odkaz:
https://doaj.org/article/b5897fea14a54e958b01f425353926f6
Autor:
Johannes Breyer, Markus Eckstein, Danijel Sikic, Felix Wezel, Florian Roghmann, Mirco Brehmer, Ralph M. Wirtz, Jonas Jarczyk, Philipp Erben, Veronika Bahlinger, Franziska Goldschmidt, Guido Fechner, Jack Chen, Ellen Paxinos, Michael Bates, Maximilian Haas, Friedemann Zengerling, Christian Bolenz, Maximilian Burger, Arndt Hartmann, Maximilian C. Kriegmair, BRIDGE Consortium e.V.
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-10 (2023)
Abstract To determine whether Xpert bladder cancer monitor, a noninvasive PCR-based biomarker test, can predict the need for 2nd transurethral resection of the bladder (TURB) better than clinical assessment. Patients scheduled for TURB were prospecti
Externí odkaz:
https://doaj.org/article/fa9759114ae54cec84a9f6e9dcdf03ce