Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Arnaud Périlleux"'
Autor:
Hervé Broly, Matthieu Stettler, Massimo Morbidelli, Anaïs Roulet, Thomas K. Villiger, Arnaud Périlleux, Miroslav Soos
Publikováno v:
Biotechnology Progress. 32:1123-1134
N-linked glycosylation is of key importance for the efficacy of many biotherapeutic proteins such as monoclonal antibodies (mAbs). Media components and cell culture conditions have been shown to significantly affect N-linked glycosylation during the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bf444d96b969fd735d4071881fdbfdec
https://doi.org/10.1002/btpr.2305
https://doi.org/10.1002/btpr.2305
Autor:
Matthieu Stettler, Natacha Collet, Hervé Broly, Martin Jordan, Arnaud Périlleux, Yolande Rouiller
Publikováno v:
mAbs. 5:501-511
An innovative high-throughput medium development method based on media blending was successfully used to improve the performance of a Chinese hamster ovary fed-batch medium in shaking 96-deepwell plates. Starting from a proprietary chemically-defined
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a84e33043a063ef1e440adf7b16a499e
https://doi.org/10.4161/mabs.23942
https://doi.org/10.4161/mabs.23942
Autor:
Yolande Rouiller, Arnaud Périlleux, Hervé Broly, Marie-Noëlle Vesin, Milène Marsaut, Matthieu Stettler
Publikováno v:
Biotechnology Progress. 28:803-813
Glucocorticoids are known to modulate various cellular functions such as cell proliferation, metabolism, glycosylation, and secretion of many proteins. We tested the effect of hydrocortisone (HC) on cell growth, viability, metabolism, protein product
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::697da092aeba65f702958f49825254a8
https://doi.org/10.1002/btpr.1530
https://doi.org/10.1002/btpr.1530
Minimizing hydrodynamic stress in mammalian cell culture through the lobed Taylor-Couette bioreactor
Autor:
Hervé Broly, Robin A. Sorg, Timm Tanzeglock, Massimo Morbidelli, Arnaud Périlleux, Miroslav Soos, Thomas Solacroup
Publikováno v:
Biotechnology Journal. 6:1504-1515
The objective of the present study was to investigate the effect of hydrodynamic stress heterogeneity on metabolism and productivity of an industrial mammalian cell line. For this purpose, a novel Lobed Taylor-Couette (LTC) mixing unit combining a na
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63e8863e50b23cc64b2f2b6728086c8a
https://doi.org/10.1002/biot.201000477
https://doi.org/10.1002/biot.201000477
Autor:
Thomas K, Villiger, Anaïs, Roulet, Arnaud, Périlleux, Matthieu, Stettler, Hervé, Broly, Massimo, Morbidelli, Miroslav, Soos
N-linked glycosylation is of key importance for the efficacy of many biotherapeutic proteins such as monoclonal antibodies (mAbs). Media components and cell culture conditions have been shown to significantly affect N-linked glycosylation during the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::00388ff405fc2dbeacbfccd911b71922
http://hdl.handle.net/11311/1024814
http://hdl.handle.net/11311/1024814
Autor:
Martin Jordan, Arnaud Périlleux, Yolande Rouiller, Marie-Noëlle Vesin, Hervé Broly, Matthieu Stettler
Publikováno v:
Biotechnology progress. 30(3)
A high-throughput DoE approach performed in a 96-deepwell plate system was used to explore the impact of media and feed components on main quality attributes of a monoclonal antibody. Six CHO-S derived clonal cell lines expressing the same monoclonal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f707a7e7bcabc28659f8a360d70b6bef
https://pubmed.ncbi.nlm.nih.gov/24777991
https://pubmed.ncbi.nlm.nih.gov/24777991