Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Arnaud Huard"'
Autor:
Bart Boersma, Viola Puddinu, Arnaud Huard, Sébastien Fauteux-Daniel, Pratyaksha Wirapati, Sofia Guedri, Jean-Christophe Tille, Thomas McKee, Mikael Pittet, Gaby Palmer, Carole Bourquin
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Inflammation plays a pivotal role in cancer development, with chronic inflammation promoting tumor progression and treatment resistance, whereas acute inflammatory responses contribute to protective anti-tumor immunity. Gasdermin D (GSDMD) mediates t
Externí odkaz:
https://doaj.org/article/f4b80242743a430885ba5c660f5b5289
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Psoriasis is a common chronic inflammatory skin disease that significantly impacts the patients’ quality of life. Recent studies highlighted the function of the interleukin (IL)-1 family member IL-38 in skin homeostasis and suggested an anti-inflam
Externí odkaz:
https://doaj.org/article/867e94fdd7b3487ab0285455b4bedef1
Autor:
Zumer Naeem, Sven Zukunft, Arnaud Huard, Jiong Hu, Bruce D. Hammock, Andreas Weigert, Timo Frömel, Ingrid Fleming
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 171, Iss , Pp 116127- (2024)
The lipid content of skin plays a determinant role in its barrier function with a particularly important role attributed to linoleic acid and its derivatives. Here we explored the consequences of interfering with the soluble epoxide hydrolase (sEH) o
Externí odkaz:
https://doaj.org/article/007633b0f61941f286a9a83ad9234b49
Autor:
Pauline Hog, Silvia Kuntschar, Peter Rappl, Arnaud Huard, Andreas Weigert, Bernhard Brüne, Tobias Schmid
Publikováno v:
Biology, Vol 12, Iss 11, p 1441 (2023)
Macrophages are a highly versatile and heterogenic group of immune cells, known for their involvement in inflammatory reactions. However, our knowledge about distinct subpopulations of macrophages and their specific contribution to the resolution of
Externí odkaz:
https://doaj.org/article/3cc8ef68f91c4433a11efc69577a14bf
Autor:
Sina Gonther, Malte Bachmann, Itamar Goren, Arnaud Huard, Andreas Weigert, Jörg Köhl, Heiko Mühl
Publikováno v:
npj Regenerative Medicine, Vol 7, Iss 1, Pp 1-10 (2022)
Abstract Murine acetaminophen-induced acute liver injury (ALI) serves as paradigmatic model for drug-induced hepatic injury and regeneration. As major cause of ALI, acetaminophen overdosing is a persistent therapeutic challenge with N-acetylcysteine
Externí odkaz:
https://doaj.org/article/e86f379873054c1d874f98dfc316986b
Autor:
Peter Rappl, Silvia Rösser, Patrick Maul, Rebekka Bauer, Arnaud Huard, Yannick Schreiber, Dominique Thomas, Gerd Geisslinger, Per-Johan Jakobsson, Andreas Weigert, Bernhard Brüne, Tobias Schmid
Publikováno v:
Cell Death and Disease, Vol 12, Iss 2, Pp 1-10 (2021)
Abstract Despite the progress to understand inflammatory reactions, mechanisms causing their resolution remain poorly understood. Prostanoids, especially prostaglandin E2 (PGE2), are well-characterized mediators of inflammation. PGE2 is produced in a
Externí odkaz:
https://doaj.org/article/82e45cbb0c5e4c0696246dff61defdd3
Autor:
Evelyn Sirait-Fischer, Catherine Olesch, Annika F. Fink, Matthias Berkefeld, Arnaud Huard, Tobias Schmid, Kazuhiko Takeda, Bernhard Brüne, Andreas Weigert
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
Despite the success of immune checkpoint blockade in cancer, the number of patients that benefit from this revolutionary treatment option remains low. Therefore, efforts are being undertaken to sensitize tumors for immune checkpoint blockade, which i
Externí odkaz:
https://doaj.org/article/ab246b617c8f4cf9a5fa4b4d678e21b4
Autor:
Yingying Han, Javier Mora, Arnaud Huard, Priscila da Silva, Svenja Wiechmann, Mateusz Putyrski, Christian Schuster, Eiman Elwakeel, Guangping Lang, Anica Scholz, Tatjana Scholz, Tobias Schmid, Natasja de Bruin, Pierre Billuart, Carlo Sala, Harald Burkhardt, Michael J. Parnham, Andreas Ernst, Bernhard Brüne, Andreas Weigert
Publikováno v:
Cell Reports, Vol 27, Iss 3, Pp 835-846.e5 (2019)
Summary: Interleukin-38 (IL-38) is a cytokine of the IL-1 family with a role in chronic inflammation. However, its main cellular targets and receptors remain obscure. IL-38 is highly expressed in the skin and downregulated in psoriasis patients. We r
Externí odkaz:
https://doaj.org/article/6b0ea48022dd45428022b5ac6a3fd6d3
Autor:
Bart Boersma, Karin Möller, Lisa Wehl, Viola Puddinu, Arnaud Huard, Sébastien Fauteux-Daniel, Carole Bourquin, Gaby Palmer, Thomas Bein
Publikováno v:
Journal of Controlled Release. 351:989-1002
Inflammation is required for protective responses against pathogens and is thus essential for survival, but sustained inflammation can lead to diseases, such as atherosclerosis and cancer. Two important mediators of inflammation are the cytokines IL-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b28c1fc69f63631a82e4d09873013a0
https://doi.org/10.1016/j.jconrel.2022.09.063
https://doi.org/10.1016/j.jconrel.2022.09.063
Autor:
Alejandro Diaz-Barreiro, Gea Cereghetti, Jenna Tonacini, Dominique Talabot-Ayer, Sylvie Kieffer-Jaquinod, Arnaud Huard, Christopher Swale, Yohann Couté, Matthias Peter, Antonio Francés-Monerris, Gaby Palmer
Cytokines of the interleukin (IL)-1 family are widely expressed in epithelial surfaces, including the epidermis, where they play a key role in the maintenance of barrier integrity and host defense. A recent report associated the IL-1 family member IL
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c0aebf8d06c21d71f86527c50ff0e922
https://doi.org/10.1101/2023.03.26.534252
https://doi.org/10.1101/2023.03.26.534252
