Zobrazeno 1 - 10
of 134
pro vyhledávání: '"Arnaud Da Cruz Paula"'
Autor:
Sushmita Gordhandas, Arnaud Da Cruz Paula, Elizabeth C. Kertowidjojo, Fresia Pareja, Kimberly Dessources, Edaise M. da Silva, Fatemeh Derakhshan, Jennifer J. Mueller, Nadeem R. Abu-Rustum, M. Herman Chui, Britta Weigelt
Publikováno v:
Gynecologic Oncology Reports, Vol 53, Iss , Pp 101391- (2024)
Externí odkaz:
https://doaj.org/article/8013523ea6fd4a99a7ed9434d3ad1847
Autor:
Higinio Dopeso, Andrea M. Gazzo, Fatemeh Derakhshan, David N. Brown, Pier Selenica, Sahar Jalali, Arnaud Da Cruz Paula, Antonio Marra, Edaise M. da Silva, Thais Basili, Laxmi Gusain, Lorraine Colon-Cartagena, Shirin Issa Bhaloo, Hunter Green, Chad Vanderbilt, Steffi Oesterreich, Anne Grabenstetter, M. Gabriela Kuba, Dara Ross, Dilip Giri, Hannah Y. Wen, Hong Zhang, Edi Brogi, Britta Weigelt, Fresia Pareja, Jorge S. Reis-Filho
Publikováno v:
npj Precision Oncology, Vol 8, Iss 1, Pp 1-11 (2024)
Abstract CDH1 (E-cadherin) bi-allelic inactivation is the hallmark alteration of breast invasive lobular carcinoma (ILC), resulting in its discohesive phenotype. A subset of ILCs, however, lack CDH1 genetic/epigenetic inactivation, and their genetic
Externí odkaz:
https://doaj.org/article/2bcd7e3ff5014c2e98a7bf5bd912578b
Autor:
Tiffany Y. Sia, Zvi Yaari, Ron Feiner, Evan Smith, Arnaud Da Cruz Paula, Pier Selenica, Sital Doddi, Dennis S. Chi, Nadeem R. Abu-Rustum, Douglas A. Levine, Britta Weigelt, Martin Fleisher, Lakshmi V. Ramanathan, Daniel A. Heller, Kara Long Roche
Publikováno v:
Gynecologic Oncology Reports, Vol 51, Iss , Pp 101330- (2024)
Given the tubal origin of high-grade serous ovarian cancer (HGSC), we sought to investigate intrauterine lavage (IUL) as a novel method of biomarker detection. IUL and serum samples were collected from patients with HGSC or benign pathology. Although
Externí odkaz:
https://doaj.org/article/0ec9b8149c314a47adc99948d4bc2357
Autor:
Jing Yu, Edaise M. da Silva, Hae-Sun La, Beth Z. Clark, Jeffrey L. Fine, Gloria J. Carter, Tatiana M. Villatoro, T. Rinda Soong, Adrian V. Lee, Steffi Oesterreich, Thais Basili, Juan Blanco-Heredia, Pier Selenica, Qiqi Ye, Arnaud Da Cruz Paula, Higinio Dopeso, Andrea Gazzo, Antonio Marra, Fresia Pareja, Jorge S. Reis-Filho, Rohit Bhargava
Publikováno v:
npj Breast Cancer, Vol 9, Iss 1, Pp 1-13 (2023)
Abstract This study describes “lobular-like invasive mammary carcinomas” (LLIMCas), a group of low- to intermediate-grade invasive mammary carcinomas with discohesive, diffusely infiltrative cells showing retained circumferential membranous immun
Externí odkaz:
https://doaj.org/article/a2ffe8ff28f6494d9753ae713d6f5f51
Publikováno v:
Cells, Vol 13, Iss 7, p 561 (2024)
MicroRNAs (miRNAs) act as negative regulators for protein-coding gene expression impacting cell proliferation, differentiation, and survival. These miRNAs are frequently dysregulated in cancer and constitute classes of blood-based biomarkers useful f
Externí odkaz:
https://doaj.org/article/18d8a2b90b8e4fe0b12f949dce713698
Autor:
Elisabete Teixeira, Cláudia Fernandes, Maria Bungărdean, Arnaud Da Cruz Paula, Raquel T. Lima, Rui Batista, João Vinagre, Manuel Sobrinho-Simões, Valdemar Máximo, Paula Soares
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 3, p 1522 (2024)
In a family with Familial Non-Medullary Thyroid Carcinoma (FNMTC), our investigation using Whole-Exome Sequencing (WES) uncovered a novel germline USP42 mutation [p.(Gly486Arg)]. USP42 is known for regulating p53, cell cycle arrest, and apoptosis, an
Externí odkaz:
https://doaj.org/article/996f3778682c4c51b9a5b8294d48016d
Autor:
Lea A. Moukarzel, Lorenzo Ferrando, Arnaud Da Cruz Paula, David N. Brown, Felipe C. Geyer, Fresia Pareja, Salvatore Piscuoglio, Anastasios D. Papanastasiou, Nicola Fusco, Caterina Marchiò, Nadeem R. Abu‐Rustum, Rajmohan Murali, Edi Brogi, Hannah Y. Wen, Larry Norton, Robert A. Soslow, Anne Vincent‐Salomon, Jorge S. Reis‐Filho, Britta Weigelt
Publikováno v:
Molecular Oncology, Vol 15, Iss 4, Pp 1024-1039 (2021)
Metaplastic breast carcinoma (MBC) and uterine carcinosarcoma (UCS) are rare aggressive cancers, characterized by an admixture of adenocarcinoma and areas displaying mesenchymal/sarcomatoid differentiation. We sought to define whether MBCs and UCSs h
Externí odkaz:
https://doaj.org/article/d43d7492291245088deab363a8092b63
Autor:
Edaise M. da Silva, Pier Selenica, Mahsa Vahdatinia, Fresia Pareja, Arnaud Da Cruz Paula, Lorenzo Ferrando, Andrea M. Gazzo, Higinio Dopeso, Dara S. Ross, Ariya Bakhteri, Nadeem Riaz, Sarat Chandarlapaty, Pedram Razavi, Larry Norton, Hannah Y. Wen, Edi Brogi, Britta Weigelt, Hong Zhang, Jorge S. Reis-Filho
Publikováno v:
npj Breast Cancer, Vol 7, Iss 1, Pp 1-8 (2021)
Abstract Metaplastic breast cancers (MBCs) are characterized by complex genomes, which seem to vary according to their histologic subtype. TERT promoter hotspot mutations and gene amplification are rare in common forms of breast cancer, but present i
Externí odkaz:
https://doaj.org/article/f132c81e88b1476593e2db603427ca32
Autor:
Yanying Huo, Pier Selenica, Amar H. Mahdi, Fresia Pareja, Kelly Kyker-Snowman, Ying Chen, Rahul Kumar, Arnaud Da Cruz Paula, Thais Basili, David N. Brown, Xin Pei, Nadeem Riaz, Yongmei Tan, Yu-Xiu Huang, Tao Li, Nicola J. Barnard, Jorge S. Reis-Filho, Britta Weigelt, Bing Xia
Publikováno v:
npj Breast Cancer, Vol 7, Iss 1, Pp 1-12 (2021)
Abstract Inherited mutations in BRCA1, BRCA2, and PALB2 cause a high risk of breast cancer. Here, we conducted parallel conditional knockout (CKO) of Brca1, Palb2, and Brca2, individually and in combination, along with one copy of Trp53, in the mamma
Externí odkaz:
https://doaj.org/article/0e18ff09a2e84f079cd0677a6df9cca3
Autor:
Timothy M D'Alfonso, Fresia Pareja, Arnaud Da Cruz Paula, Mahsa Vahdatinia, Andrea Gazzo, Lorenzo Ferrando, Edaise M da Silva, Esther Cheng, Lisa Sclafani, Sarat Chandarlapaty, Hong Zhang, Syed A Hoda, Hannah Y Wen, Edi Brogi, Britta Weigelt, Jorge S Reis‐Filho
Publikováno v:
The Journal of Pathology: Clinical Research, Vol 7, Iss 2, Pp 113-120 (2021)
Abstract Juvenile papillomatosis (JP) of the breast is a rare benign mass‐forming lesion occurring in young women, which is histologically characterized by a constellation of proliferative changes and large cysts, giving it the gross appearance of
Externí odkaz:
https://doaj.org/article/f30c2cca903d4d859d3f9b547aded646