Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Arnaud Avril"'
Publikováno v:
Toxins, Vol 15, Iss 2, p 100 (2023)
Ricin toxin is a disulfide-linked glycoprotein (AB toxin) comprising one enzymatic A chain (RTA) and one cell-binding B chain (RTB) contained in the castor bean, a Ricinus species. Ricin inhibits peptide chain elongation via disruption of the binding
Externí odkaz:
https://doaj.org/article/7becd5139b1f40649ad1f26a751f9b15
Autor:
Arnaud Avril, Jean-Nicolas Tournier, Jean-Charles Paucod, Bénédicte Fournes, Philippe Thullier, Thibaut Pelat
Publikováno v:
Toxins, Vol 14, Iss 3, p 172 (2022)
Anthrax is an acute disease caused by the bacterium Bacillus anthracis, and is a potential biowarfare/bioterrorist agent. Its pulmonary form, caused by inhalation of the spores, is highly lethal and is mainly related to injury caused by the toxins se
Externí odkaz:
https://doaj.org/article/f3c1b749509f406e95b76123ffd8392e
Autor:
Maria Lucia Orsini Delgado, Arnaud Avril, Julie Prigent, Julie Dano, Audrey Rouaix, Sylvia Worbs, Brigitte G. Dorner, Clémence Rougeaux, François Becher, François Fenaille, Sandrine Livet, Hervé Volland, Jean-Nicolas Tournier, Stéphanie Simon
Publikováno v:
Toxins, Vol 13, Iss 2, p 100 (2021)
Ricin, a highly toxic protein from Ricinus communis, is considered a potential biowarfare agent. Despite the many data available, no specific treatment has yet been approved. Due to their ability to provide immediate protection, antibodies (Abs) are
Externí odkaz:
https://doaj.org/article/760dd99b883743a88707867304cec55c
Autor:
Sebastian Miethe, Christelle Mazuet, Yvonne Liu, Robert Tierney, Christine Rasetti-Escargueil, Arnaud Avril, André Frenzel, Philippe Thullier, Thibaut Pelat, Remi Urbain, Alexandre Fontayne, Dorothea Sesardic, Michael Hust, Michel Robert Popoff
Publikováno v:
PLoS ONE, Vol 11, Iss 8, p e0161446 (2016)
Botulinum neurotoxins (BoNTs) are counted among the most toxic substances known and are responsible for human botulism, a life-threatening disease characterized by flaccid muscle paralysis that occurs naturally by food poisoning or colonization of th
Externí odkaz:
https://doaj.org/article/3dfe8169d86e47538b9d3a846c6718a2
Autor:
Christine Rasetti-Escargueil, Arnaud Avril, Sebastian Miethe, Christelle Mazuet, Yagmur Derman, Katja Selby, Philippe Thullier, Thibaut Pelat, Remi Urbain, Alexandre Fontayne, Hannu Korkeala, Dorothea Sesardic, Michael Hust, Michel R. Popoff
Publikováno v:
Toxins, Vol 9, Iss 10, p 309 (2017)
The goal of the AntiBotABE Program was the development of recombinant antibodies that neutralize botulinum neurotoxins (BoNT) A, B and E. These serotypes are lethal and responsible for most human botulinum cases. To improve therapeutic efficacy, the
Externí odkaz:
https://doaj.org/article/424bc2d0ad4943e583c273befd72cfe0
Autor:
Sebastian Miethe, Christine Rasetti-Escargueil, Arnaud Avril, Yvonne Liu, Siham Chahboun, Hannu Korkeala, Christelle Mazuet, Michel-Robert Popoff, Thibaut Pelat, Philippe Thullier, Dorothea Sesardic, Michael Hust
Publikováno v:
PLoS ONE, Vol 10, Iss 10, p e0139905 (2015)
Botulinum neurotoxins (BoNTs) are considered to be the most toxic substances known on earth and are responsible for human botulism, a life-threatening disease characterized by flaccid muscle paralysis that occurs naturally by food-poisoning or coloni
Externí odkaz:
https://doaj.org/article/f9e47233b8c54c6186db6486b060e678
Autor:
Philippe Thullier, Arnaud Avril, Jacques Mathieu, Christian K Behrens, Jean-Luc Pellequer, Thibaut Pelat
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e65855 (2013)
The lethal toxin (LT) of Bacillus anthracis, composed of the protective antigen (PA) and the lethal factor (LF), plays an essential role in anthrax pathogenesis. PA also interacts with the edema factor (EF, 20% identity with LF) to form the edema tox
Externí odkaz:
https://doaj.org/article/011a98f4ab824f9eba5389c025c766fe
Autor:
Yağmur Derman, Katja Selby, Sebastian Miethe, André Frenzel, Yvonne Liu, Christine Rasetti-Escargueil, Arnaud Avril, Thibaut Pelat, Remi Urbain, Alexandre Fontayne, Philippe Thullier, Dorothea Sesardic, Miia Lindström, Michael Hust, Hannu Korkeala
Publikováno v:
Toxins, Vol 8, Iss 9, p 257 (2016)
Botulinum neurotoxins (BoNTs) cause botulism and are the deadliest naturally-occurring substances known to humans. BoNTs have been classified as one of the category A agents by the Centers for Disease Control and Prevention, indicating their potentia
Externí odkaz:
https://doaj.org/article/e6ae5f8316ed4cf0bfb1033ad2975a5e
Autor:
Stéphanie Simon, Hervé Volland, Arnaud Avril, François Becher, Clémence Rougeaux, Sandrine Livet, François Fenaille, Jean-Nicolas Tournier, Julie Dano, Sylvia Worbs, Julie Prigent, Brigitte G. Dorner, Maria Lucia Orsini Delgado, Audrey Rouaix
Publikováno v:
Toxins
Toxins, 2021, 13 (2), ⟨10.3390/toxins13020100⟩
Toxins, MDPI, 2021, 13 (2), ⟨10.3390/toxins13020100⟩
Toxins, Vol 13, Iss 100, p 100 (2021)
Volume 13
Issue 2
Toxins, 2021, 13 (2), ⟨10.3390/toxins13020100⟩
Toxins, MDPI, 2021, 13 (2), ⟨10.3390/toxins13020100⟩
Toxins, Vol 13, Iss 100, p 100 (2021)
Volume 13
Issue 2
Ricin, a highly toxic protein from Ricinus communis, is considered a potential biowarfare agent. Despite the many data available, no specific treatment has yet been approved. Due to their ability to provide immediate protection, antibodies (Abs) are
Autor:
Arnaud, Avril
Publikováno v:
Advances in experimental medicine and biology. 1053
Diseases can be caused naturally by biological agents such as bacteria, viruses and toxins (natural risk). However, such biological agents can be intentionally disseminated in the environment by a State (military context) or terrorists to cause disea