Targeting the Human 80S Ribosome in Cancer: From Structure to Function and Drug Design for Innovative Adjuvant Therapeutic Strategies

Autor: Arnaud Gilles, Léo Frechin, Kundhavai Natchiar, Giulia Biondani, Ottilie von Loeffelholz, Samuel Holvec, Julie-Lisa Malaval, Jean-Yves Winum, Bruno P. Klaholz, Jean-François Peyron

Publikováno v: Cells, Vol 9, Iss 3, p 629 (2020)

The human 80S ribosome is the cellular nucleoprotein nanomachine in charge of protein synthesis that is profoundly affected during cancer transformation by oncogenic proteins and provides cancerous proliferating cells with proteins and therefore biom

Externí odkaz: https://doaj.org/article/51a51ba49fdd41e1becad79ba38ba959

The Uranie platform: an open-source software for optimisation, meta-modelling and uncertainty analysis

Autor: Blanchard Jean-Baptiste, Damblin Guillaume, Martinez Jean-Marc, Arnaud Gilles, Gaudier Fabrice

Publikováno v: EPJ Nuclear Sciences & Technologies, Vol 5, p 4 (2019)

The high-performance computing resources and the constant improvement of both numerical simulation accuracy and the experimental measurements with which they are confronted bring a new compulsory step to strengthen the credence given to the simulatio

Externí odkaz: https://doaj.org/article/b334c7efacdc4ace99047e8dd0b4f224

Developing in‐company research: a French review of observation strategies

Autor: Arnaud, Gilles

Publikováno v: Management Decision, 2002, Vol. 40, Issue 2, pp. 101-115.

Externí odkaz: http://www.emeraldinsight.com/doi/10.1108/00251740210422785

'Travaillez comme vous êtes!': un regard psychosocial sur la mode de l'authenticité en entreprise

Autor: Flamme, Kevin, Arnaud, Gilles

Publikováno v: ESCP Impact Paper
ESCP Impact Paper, 2021
Better Business: Creating sustainable value-ESCP Impact Papers Second Edition
ESCP. Better Business: Creating sustainable value-ESCP Impact Papers Second Edition, 2021

International audience; L’exemple récent d’un cabinet de conseil, mandaté pour réinventer l’organisation du travaild’une Entreprise Solidaire d’Utilité Sociale, témoigne d’une stratégie managérialeémergente visant à développer l

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::0c098160860f35fb32233604d919a189
https://hal-uco.archives-ouvertes.fr/hal-03510833

Bis[μ-1-hexyl-3-(2,3,5,6,8,9,11,12-octahydro-1,4,7,10,13-benzopentaoxacyclopentadecin-15-yl)urea]bis(azidosodium) chloroform disolvate

Autor: Mihail Barboiu, Arie van der Lee, Yves-Marie Legrand, Arnaud Gilles

Publikováno v: Acta Crystallographica Section E, Vol 68, Iss 5, Pp m609-m610 (2012)

In the title compound, [Na2(N3)2(C21H34N2O6)2]·2CHCl3, the sodium cation is heptacoordinated by five O atoms of the crown ether unit of the 1-hexyl-3-(2,3,5,6,8,9,11,12-octahydro-1,4,7,10,13-benzopentaoxacyclopentadecin-15-yl)urea (L) ligand, the O

Externí odkaz: https://doaj.org/article/e260e8123e624251aff056abac839a75