Figure S1 from The E3 Ubiquitin Ligase Asb2α in T Helper 2 Cells Negatively Regulates Antitumor Immunity in Colorectal Cancer

Autor: Pierre G. Lutz, Christel Moog-Lutz, Chanaëlle Febrissy, Arnaud Métais, Isabelle Lamsoul, Camille A. Spinner

Figure S1 shows the numbers of dendritic cells, macrophages and B cells in the colon, and the numbers of dendritic cells in the mesenteric lymph nodes of control and cKO mice treated with AOM and DSS.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07ecb5993d6c8c4213645afe3d469f19
https://doi.org/10.1158/2326-6066.22542180

Data from The E3 Ubiquitin Ligase Asb2α in T Helper 2 Cells Negatively Regulates Antitumor Immunity in Colorectal Cancer

Autor: Pierre G. Lutz, Christel Moog-Lutz, Chanaëlle Febrissy, Arnaud Métais, Isabelle Lamsoul, Camille A. Spinner

The escape of cancer cells from host immunosurveillance involves a shift in immune responses, including an imbalance in Th1 and Th2 cells. A Th1-dominated immune response predicts positive outcomes in colorectal cancer. The E3 ubiquitin ligase, Asb2�

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0cc4bb5c61bacb9e3f2e303147eab29e
https://doi.org/10.1158/2326-6066.c.6549825.v1

Productive HIV-1 infection of tissue macrophages by fusion with infected CD4+ T cells

Autor: Rémi Mascarau, Marie Woottum, Léa Fromont, Rémi Gence, Vincent Cantaloube-Ferrieu, Zoï Vahlas, Kevin Lévêque, Florent Bertrand, Thomas Beunon, Arnaud Métais, Hicham El Costa, Nabila Jabrane-Ferrat, Yohan Gallois, Nicolas Guibert, Jean-Luc Davignon, Gilles Favre, Isabelle Maridonneau-Parini, Renaud Poincloux, Bernard Lagane, Serge Bénichou, Brigitte Raynaud-Messina, Christel Vérollet

Publikováno v: Journal of Cell Biology. 222

Macrophages are essential for HIV-1 pathogenesis and represent major viral reservoirs. Therefore, it is critical to understand macrophage infection, especially in tissue macrophages, which are widely infected in vivo, but poorly permissive to cell-fr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::84a49f5a2f95ad5adfbbf97a84712fff
https://doi.org/10.1083/jcb.202205103

Host phospholipid peroxidation fuels ExoU-dependent cell necrosis and supports $Pseudomonas\ aeruginosa$-driven pathology

Autor: Flavie Moreau, Geanncarlo Lugo-Villarino, Aurélien Boyance, Arnaud Métais, Peter J. Peters, Karin Santoni, Céline Cougoule, Stephen Adonai Leon-Icaza, Hans Clevers, Lise Lefèvre, Etienne Meunier, Yoann Rombouts, Agnès Coste, Pierre-Jean Bordignon, Miriam Pinilla, Emmanuelle Naser, Audrey Hessel, David Péricat, Ina Attrée, Rémi Planès, Nino Iakobachvili, Dara W. Frank, Elif Eren, Salimata Bagayoko, Céline Berrone

Publikováno v: PLoS Pathogens
PLoS Pathogens, 2021, 17 (9), pp.e1009927. ⟨10.1371/journal.ppat.1009927⟩
PLOS Pathogens
PLoS Pathogens, 17(9). Public Library of Science
PLoS Pathogens, Vol 17, Iss 9, p e1009927 (2021)
PLoS Pathogens, Public Library of Science, 2021, 17 (9), pp.e1009927. ⟨10.1371/journal.ppat.1009927⟩
PLOS PATHOGENS, 17(9):e1009927. Public Library of Science

Regulated cell necrosis supports immune and anti-infectious strategies of the body; however, dysregulation of these processes drives pathological organ damage. Pseudomonas aeruginosa expresses a phospholipase, ExoU that triggers pathological host cel

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e894e6c2b90a46e338f26354fa5a061
https://hal.science/hal-03355818/document

A Pulmonary

Autor: Lucie, Bernard-Raichon, André, Colom, Sarah C, Monard, Amine, Namouchi, Margaux, Cescato, Hugo, Garnier, Stephen A, Leon-Icaza, Arnaud, Métais, Alexia, Dumas, Dan, Corral, Natsinet, Ghebrendrias, Pauline, Guilloton, Christel, Vérollet, Denis, Hudrisier, Aude, Remot, Philippe, Langella, Muriel, Thomas, Céline, Cougoule, Olivier, Neyrolles, Geanncarlo, Lugo-Villarino

Publikováno v: Journal of immunology (Baltimore, Md. : 1950). 207(7)

The lungs harbor multiple resident microbial communities, otherwise known as the microbiota. There is an emerging interest in deciphering whether the pulmonary microbiota modulate local immunity, and whether this knowledge could shed light on mechani

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::64bf0f342baebc91aadab385c6faa391
https://pubmed.ncbi.nlm.nih.gov/34479945